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PHENYLBIGUANIDE

Product Name
PHENYLBIGUANIDE
CAS No.
102-02-3
Chemical Name
PHENYLBIGUANIDE
Synonyms
p1426;phenyl-biguanid;PHENYLBIGUANIDE;phenyldiguanide;1-PHENYLBIGUANIDE;1-phenyl-biguanid;N-Phenylbiguanide;Phenylbiguanide>n-phenyl-n’-guanylguanidine;2-(N2-Phenylamidino)guanidine
CBNumber
CB5676800
Molecular Formula
C8H11N5
Formula Weight
177.21
MOL File
102-02-3.mol
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PHENYLBIGUANIDE Property

Melting point:
135-142 °C (lit.)
Boiling point:
299.13°C (rough estimate)
Density 
1.2512 (rough estimate)
refractive index 
1.6900 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
alcohol: freely soluble
pka
10.76, 2.13(at 25℃)
form 
powder to crystal
color 
White to Orange to Green
Merck 
14,7276
InChIKey
CUQCMXFWIMOWRP-UHFFFAOYSA-N
CAS DataBase Reference
102-02-3(CAS DataBase Reference)
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Safety

WGK Germany 
3
RTECS 
DU2450000
HS Code 
2925.29.6000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
164216
Product name
1-Phenylbiguanide
Purity
98%
Packaging
25g
Price
$435
Updated
2025/07/31
TCI Chemical
Product number
P1002
Product name
Phenylbiguanide
Purity
>98.0%(T)
Packaging
5g
Price
$205
Updated
2025/07/31
TCI Chemical
Product number
P1002
Product name
Phenylbiguanide
Purity
>98.0%(T)
Packaging
10g
Price
$347
Updated
2025/07/31
TRC
Product number
P319933
Product name
1-Phenylbiguanide
Packaging
50g
Price
$220
Updated
2021/12/16
ChemScene
Product number
CS-0021169
Product name
Phenylbiguanide
Purity
>98.0%
Packaging
100mg
Price
$50
Updated
2021/12/16
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PHENYLBIGUANIDE Chemical Properties,Usage,Production

Uses

1-Phenylbiguanide is a 5-hydroxytryptamine receptor agonist.

Definition

ChEBI: A member of the class of biguanides that is biguanide in which one of the terminal nitrogen atoms is substituted by a phenyl group.

General Description

1-Phenylbiguanide is a 5-hydroxytryptamine receptor agonist and increases extracellular dopamine release in rat nucleus accumbens in vivo. It serves as building block for synthesis of heterocyclic compounds.

in vivo

In anaesthetised mice, Phenylbiguanide (PBG), a drug that is known to stimulate cardiopulmonary afferent C-fibres,is injected into the right atrium of the heart and mapped c-Fos expression within specific regions of the central nervous system. Intraatrial injection of PBG produces a reflex cardiorespiratory response including a pronounced bradycardia and a respiratory depression[3].

IC 50

5-HT3 Receptor: 3 μM (EC50)

Purification Methods

Crystallise the biguanide from water or toluene. [Beilstein 12 H 370, 12 I 236, 12 III 807.]

PHENYLBIGUANIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from PHENYLBIGUANIDE manufacturers

Career Henan Chemical Co
Product
PHENYLBIGUANIDE 102-02-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2020-03-04

102-02-3, PHENYLBIGUANIDERelated Search:

1,3-Diphenyl-1,1,3,3-tetramethyldisiloxane N,N'-Diphenylurea 1-(4-FLUOROPHENYL)BIGUANIDE HYDROCHLORIDE Biguanide o-Tolyl biguanide N-(4-CHLOROPHENYL)-N'-(ISOPROPYL)-IMIDODICARBONIMIDIC DIAMIDE PHENYLBIGUANIDE 1-PHENYLBIGUANIDE MONOHYDROCHLORIDE,1-PHENYLBIGUANIDE HYDROCHLORIDE 1-(4-TRIFLUOROMETHYL)PHENYLBIGUANIDE HYDROCHLORIDE SALT 96% 4-(TRIFLUOROMETHYL)PHENYLBIGUANIDE HYDROCHLORIDE,1-(4-TRIFLUOROMETHYL)PHENYLBIGUANIDE, H&,1-(4-TRIFLUOROMETHYL)PHENYLBIGUANIDE HYDROCHLORIDE 1-Methyl-1-phenylbiguanide 1-phenylbiguanide, compound with benzothiazole-2(3H)-thione (1:1) PHENYLBIGUANIDE MBT SALT 1G [R] PHENYLBIGUANIDE MBT SALT 1-(A-BENZOYLBENZYLIDENE)-5-PHENYLBIGUANIDE 6,6-DIMETHYL-N2-PHENYL-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE SPECS AG-690/12767754 3-(4-(2-CHLOROBENZYLOXY)PHENYL)-N-PHENYL-5-(PIPERIDIN-1-YL)-2,3-DIHYDRO-[1,2,4]TRIAZOLO[4,3-A][1,3,5]TRIAZIN-7-AMINE

  • phenyldiguanide
  • 1-PHENYLBIGUANIDE
  • N-PHENYLIMINODICARBONIMIDIC-DIAMIDE
  • PHENYLBIGUANIDE
  • 2-(N2-Phenylamidino)guanidine
  • 1-phenyl-biguanid
  • n-phenyl-n’-guanylguanidine
  • p1426
  • phenyl-biguanid
  • Phenylbiguanide (Synonyms: N-Phenylbiguanide
  • Phenylbiguanide (N-Phenylbiguanide
  • Phenylbiguanide&gt
  • N-Phenylbiguanide
  • Imidodicarbonimidic diamide, N-phenyl-
  • 5-hydroxytryptamine Receptor,Phenylbiguanide,inhibit,Serotonin Receptor,Inhibitor,5-HT Receptor
  • 1-Phenylbiguanide, 5-HT3 receptor agonist
  • Phenylbiguanide, 10 mM in DMSO
  • 102-02-3
  • C8H11N5
  • C6H5NHCNHNHCNH
  • C6H5NHCNHNHCNHNH2
  • Building Blocks
  • Guanidines
  • Organic Building Blocks
  • Nitrogen Compounds
  • AgonistsOrganic Building Blocks
  • Guanidines
  • Neurotransmitters
  • Nitrogen Compounds
  • Serotonergics