ChemicalBook > CAS DataBase List > (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID

(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID

Product Name
(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
CAS No.
100828-16-8
Chemical Name
(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
Synonyms
cppp;DL-CPP;3-2-Cpp;(RS)-CPP;(+/-)-CPP;(RS) CPP,(RS)CPP;(R,S)-CPP, NMDA antagonist;(+/-)-CPP POTENT AND SELECTIVE;4-(3-Phosphonopropyl)-2-piperazinecarboxylic acid;4-(3-phosphonopropyl)piperazine-2-carboxylic acid
CBNumber
CB5677423
Molecular Formula
C8H17N2O5P
Formula Weight
252.2
MOL File
100828-16-8.mol
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(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID Property

Boiling point:
546.7±60.0 °C(Predicted)
Density 
1.408±0.06 g/cm3(Predicted)
storage temp. 
Desiccate at RT
solubility 
H2O: 99.2 mg/mL
form 
solid
pka
1.89±0.20(Predicted)
color 
white
Water Solubility 
Soluble to 100 mM in water
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C104
Product name
(±)-CPP
Purity
solid
Packaging
5mg
Price
$221
Updated
2024/03/01
Sigma-Aldrich
Product number
C104
Product name
(±)-CPP
Purity
solid
Packaging
25mg
Price
$757
Updated
2024/03/01
Sigma-Aldrich
Product number
C104
Product name
(±)-CPP
Purity
solid
Packaging
100mg
Price
$2560
Updated
2024/03/01
Tocris
Product number
0173
Product name
(RS)-CPP
Packaging
50
Price
$818
Updated
2021/12/16
Tocris
Product number
0173
Product name
(RS)-CPP
Packaging
10
Price
$195
Updated
2021/12/16
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(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID Chemical Properties,Usage,Production

Uses

(+)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphoric Acid is a compound with NMDA antagonistic activity.

Synthesis Reference(s)

Tetrahedron Letters, 30, p. 5193, 1989 DOI: 10.1016/S0040-4039(01)93739-6

Biological Activity

Potent NMDA antagonist. See separate isomer (3-((R)-2-Carboxypiperazin-4-yl)-propyl-1-phosphonicacid ).

Biochem/physiol Actions

Potent and selective NMDA glutamate receptor antagonist; anticonvulsant.

storage

Room temperature (desiccate)

(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID Suppliers

China 20 Germany 2 India 1 Japan 1 South Korea 1 Switzerland 1 Ukraine 1 United Kingdom 2 United States 8 Global 37

100828-16-8, (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACIDRelated Search:

2-Piperazinemethanol 4-METHYLPIPERAZINE-2-CARBOXYLIC ACID 3-((R)-2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID,R(-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID 3-Aminopropylphosphonic acid (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID 2,3-Diaminopropionic acid 2-Methylpiperazine PIPERAZINE-2-CARBOXYLIC ACID 2-Piperazinecarboxaldehyde (+/-)-3-(2-CARBOXY-PIPERAZIN-4-YL) PROPYL-1-PHOSPHONIC ACID-[PROPYL-1,2-3H]- azaleucine

  • (RS)-CPP
  • (RS)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
  • (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
  • DL-CPP
  • (+/-)-CPP
  • (+/-)-CPP POTENT AND SELECTIVE
  • 2-Piperazinecarboxylic acid, 4-(3-phosphonopropyl)-
  • 2-Piperazinecarboxylic acid, 4-(3-phosphonopropyl)-, (+-)-
  • 3-2-Cpp
  • 4-(3-Phosphonopropyl)-2-piperazinecarboxylic acid
  • Dl-3-(2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid
  • 4-(3-phosphonopropyl)piperazine-2-carboxylic acid
  • (+)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphoric Acid
  • cppp
  • (+)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphoricAcid
  • (RS) CPP,(RS)CPP
  • (+/-)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid
  • (R,S)-CPP, NMDA antagonist
  • 100828-16-8
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • Ligand-Gated Ion Channels
  • Ion Channels
  • Ionotropic Glutamate Receptor Modulators
  • Glutamate receptor
  • pharmaceutical intermediates