beta-Cyclodextrin methyl ethers

Product Name: beta-Cyclodextrin methyl ethers
CAS No.: 128446-36-6
Chemical Name: beta-Cyclodextrin methyl ethers
Synonyms: Methyl-β-cyclodextrin;MBC;METHYL-BETA-CYCLODEXTRIN;Me-β-CD;Methyl-beta-cyclodextrine;MBCD;MEBCD;Me-β-CD;BETA-CYD;RM-β-CD-o
CBNumber: CB5696215
Molecular Formula: C54H94O35
Formula Weight: 1303.3
MOL File: 128446-36-6.mol

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beta-Cyclodextrin methyl ethers Property

Melting point:: 180-182 °C(lit.)
alpha: +159°(25℃, c=1, H2O)
Flash point:: 187 °C
storage temp.: room temp
solubility: H2O: soluble50mg/mL
form: powder
color: White to off-white
optical activity: [α]25/D +159°, c = 1 in H2O
Water Solubility: Soluble in water
InChIKey: YZOUYRAONFXZSI-SBHWVFSVSA-N
LogP: -2.566 (est)
EPA Substance Registry System: .beta.-Cyclodextrin, methyl ethers (128446-36-6)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
TSCA: Yes
HS Code: 35051000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 332615
Product name: Methyl-β-cyclodextrin
Purity: average Mn 1310
Packaging: 5g
Price: $52.5
Updated: 2024/03/01

Sigma-Aldrich

Product number: 332615
Product name: Methyl-β-cyclodextrin
Purity: average Mn 1310
Packaging: 25g
Price: $171
Updated: 2024/03/01

TCI Chemical

Product number: M1356
Product name: Methyl-β-cyclodextrin (mixture of several Methylated)
Packaging: 25g
Price: $109
Updated: 2024/03/01

TCI Chemical

Product number: M1356
Product name: Methyl-β-cyclodextrin (mixture of several Methylated)
Packaging: 250g
Price: $544
Updated: 2024/03/01

Alfa Aesar

Product number: J66847
Product name: Methyl-beta-cyclodextrin
Packaging: 5g
Price: $47.5
Updated: 2024/03/01

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beta-Cyclodextrin methyl ethers Chemical Properties,Usage,Production

Description

Methyl-β-cyclodextrin is a randomly methylated form of the cyclic oligosaccharide β-cyclodextrin . Methyl-β-cyclodextrin contains seven D-(+)-glucopyranose units that contain randomized hydrogen or methyl groups. Methyl-β-cyclodextrin has been used to improve the aqueous solubility of various compounds and to extract cholesterol from lipid membranes. Methyl-β-cyclodextrin (5 mM) reduces α-synuclein levels in the membrane and detergent-insoluble fractions from B103 neuroblastoma cells transfected with human α-synuclein. It also reduces α-synuclein levels in mouse brain in a transgenic model of α-synucleinopathy.

Chemical Properties

White powder

Uses

substrate for laminarinase and other glucanases

Uses

Cavity size is the major determinant as to which cyclodextrin is used in complexation. The cavity diameter of β-cyclodextrins or β-glucopyranose unit compounds is well-suited for use with molecules the size of hormones, vitamins and many compounds frequently used in tissue and cell culture applications. For this reason, β-cyclodextrin is most commonly used as a complexing agent. It is used to increase the solubility of non-polar substances such as fatty acids, lipids, vitamins and cholesterol for use in cell culture applications. Methyl-β-cyclodextrin is used to remove cholesterol from cultured cells and is employed to remove lipid rafts.

Uses

Methyl-β-cyclodextrin is a cholesterol-removing agent mainly used for lipid raft disruption. It may also be used for detergent removal from protein-lipid-detergent ternary mixture to produce 2D membrane protein crystals due to its high solubility and affinity for detergents generally used in membrane protein chemistry.

General Description

Methyl-β-cyclodextrin is a small cyclic heptasaccharide.

Biochem/physiol Actions

Methyl-β-cyclodextrin participates in increasing the permeability of cells. It also plays a role in depolymerizing the actin cytoskeleton in cells. Methyl-β-cyclodextrin is involved in attracting cholesterol from the plasma. It participates in activating extracellular receptor kinase in certain cells.

beta-Cyclodextrin methyl ethers Preparation Products And Raw materials

Raw materials

Preparation Products

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beta-Cyclodextrin methyl ethers Suppliers

Americas 1 Canada 1 China 306 Europe 3 France 1 Germany 2 India 2 Japan 3 Switzerland 1 United Kingdom 9 United States 21 Global 350

Shanghai JONLN Reagent Co., Ltd.

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XiaoGan ShenYuan ChemPharm co,ltd

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View Lastest Price from beta-Cyclodextrin methyl ethers manufacturers

Shandong Deshang Chemical Co., Ltd.

Product: beta-Cyclodextrin methyl ethers 128446-36-6
Price: US $10.00-7.00/kg
Min. Order: 1kg
Purity: 99.99%
Supply Ability: 10 tons
Release date: 2024-06-14

Hebei Guanlang Biotechnology Co., Ltd.

Product: beta-Cyclodextrin methyl ethers 128446-36-6
Price: US $10.00/Kg/Drum
Min. Order: 1KG
Purity: 99.5%
Supply Ability: 100 TON
Release date: 2020-11-20

Hebei Guanlang Biotechnology Co., Ltd.

Product: beta-Cyclodextrin methyl ethers 128446-36-6
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5tons
Release date: 2021-10-21

128446-36-6, beta-Cyclodextrin methyl ethersRelated Search:

Tribenuron methyl Thiophanate-methyl gamma-Cyclodextrin POLY(METHYLSILSESQUIOXANE) 2,6-Lutidine CYCLODEXTRIN beta-Cyclodextrin hydrate Methyl salicylate Methyl acetate Kresoxim-methyl 2,6-DI-O-METHYL-BETA-CYCLODEXTRIN METSULFURON METHYL 2-Hydroxypropyl-β-cyclodextrin β-Cyclodextrin Calcium lactate Methyl METHYL BETA-D-GLUCOPYRANOSIDE alpha-D-Methylglucoside

.beta.-cyclodextrin,methylethers

METHYL-BETA-CYCLODEXTRIN

MBC

BETA-W7 M1.8

BETA-CYD

(Mixture of several Methylated)

Methyl-beta-cyclodextrin&nbsp

Methyl-beta-cyclodextrin (mixture of several Methylated)

Methyl-β-cyclodextrin [average M.W. 1310]

Me-β-CD

Methyl-β-cyclodextrin (Mixture of several Methylated)

Methylated-B-cyclodextrin

Cavasol? W7 M

Cavasol? W7 M PH

Methylated-β-Cyclodextrin

Methyl-beta-cyclodextrin Produced by Wacker Chemie AG, Burghausen, Germany, Life Science, >=98.0% cyclodextrin basis

MEBCD

Methyl-beta-cyclodextrin(Me-β-CD)

Methylophioponanone B

β-Cyclodextrin methyl ethers

Methyl-β-cyclodextrin, Average Mn approx. 1310

RM-β-CD-o

Randomly methylated-β-Cyclodextrin

pharmaceutical grade beta-Cyclodextrin methyl ethers

pharmaceutical grade MEBCD

pharmaceutical grade Methylated-beta-Cyclodextrin

pharmaceutical grade Methylated-β-Cyclodextrin

pharmaceutical grade methyl-B-cyclodextrin

pharmaceutical grade Methyl-beta-cyclodextrin (mixture of several Methylated)

pharmaceutical grade Methyl--cyclodextrin

pharmaceutical grade methyl-β-cyclodextrin

pharmaceutical grade Me-β-CD

pharmaceutical grade methyl-beta-cyclodextrin

Methyl-b-cyclodextrin - 3 to 9 degree of substitution

Heptapkis ( 2,6-di-o-Methyl)-β-cyclodextrin

METHYL-BETA-CYCLODEXTRIN;MΒCD

Methyl-beta-cyclodextrin (DS~12)

Dimethyl-β-Cyclodextrin

Methyl-?cyclodextrin

methyl-B-cyclodextrin cell culture*tested

methyl-β-cyclodextrin cyclomaltoheptaose, methylether

(RANDOM) METHYL BETA CYCLODEXTRIN,*TECHNICAL GRADE

METHYL-B-CYLODEXTRIN NON-TOXIC SOLUBILIZ ER

(RANDOM) METHYL BETA-CYCLODEXTRIN,*PHARMACEUTICAL G

Methyl-Beta-cyclodextrin=Cyclodextrinmethyle

METHYL-SS-CYCLODEXTRIN

B-Cyclodextrin methyl ether

METHYL B-CYCLODEXTRIN

Methyl-beta-cyclodextrin,average Mn ~1310

Methyl-beta-cyclodextrin (Mixture of Methylated)

Methyl-β-cyclodextrin

Methyl-beta-cyclodextrine

hot selling beta-Cyclodextrin methyl ethers

top quality beta-Cyclodextrin methyl ethers

beta-Cyclodextrin methyl ethers USP/EP/BP

Methyl-β-cyclodextrin (Mixture of Methylated)

β-Cyclodextrin, methyl ethers

beta-Cyclodextrin methyl ethers cyclodextrin