ChemicalBook > CAS DataBase List > beta-Cyclodextrin methyl ethers

beta-Cyclodextrin methyl ethers

Product Name
beta-Cyclodextrin methyl ethers
CAS No.
128446-36-6
Chemical Name
beta-Cyclodextrin methyl ethers
Synonyms
Methyl-β-cyclodextrin;MBC;METHYL-BETA-CYCLODEXTRIN;Me-β-CD;Methyl-beta-cyclodextrine;MBCD;MEBCD;Me-β-CD;BETA-CYD;RM-β-CD-o
CBNumber
CB5696215
Molecular Formula
C54H94O35
Formula Weight
1303.3
MOL File
128446-36-6.mol
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beta-Cyclodextrin methyl ethers Property

Melting point:
180-182 °C(lit.)
alpha 
+159°(25℃, c=1, H2O)
Flash point:
187 °C
storage temp. 
room temp
solubility 
H2O: soluble50mg/mL
form 
powder
color 
White to off-white
optical activity
[α]25/D +159°, c = 1 in H2O
Water Solubility 
Soluble in water
InChIKey
YZOUYRAONFXZSI-SBHWVFSVSA-N
LogP
-2.566 (est)
EPA Substance Registry System
.beta.-Cyclodextrin, methyl ethers (128446-36-6)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
TSCA 
Yes
HS Code 
35051000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
332615
Product name
Methyl-β-cyclodextrin
Purity
average Mn 1310
Packaging
5g
Price
$52.5
Updated
2024/03/01
Sigma-Aldrich
Product number
332615
Product name
Methyl-β-cyclodextrin
Purity
average Mn 1310
Packaging
25g
Price
$171
Updated
2024/03/01
TCI Chemical
Product number
M1356
Product name
Methyl-β-cyclodextrin (mixture of several Methylated)
Packaging
25g
Price
$109
Updated
2024/03/01
TCI Chemical
Product number
M1356
Product name
Methyl-β-cyclodextrin (mixture of several Methylated)
Packaging
250g
Price
$544
Updated
2024/03/01
Alfa Aesar
Product number
J66847
Product name
Methyl-beta-cyclodextrin
Packaging
5g
Price
$47.5
Updated
2024/03/01
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beta-Cyclodextrin methyl ethers Chemical Properties,Usage,Production

Description

Methyl-β-cyclodextrin is a randomly methylated form of the cyclic oligosaccharide β-cyclodextrin . Methyl-β-cyclodextrin contains seven D-(+)-glucopyranose units that contain randomized hydrogen or methyl groups. Methyl-β-cyclodextrin has been used to improve the aqueous solubility of various compounds and to extract cholesterol from lipid membranes. Methyl-β-cyclodextrin (5 mM) reduces α-synuclein levels in the membrane and detergent-insoluble fractions from B103 neuroblastoma cells transfected with human α-synuclein. It also reduces α-synuclein levels in mouse brain in a transgenic model of α-synucleinopathy.

Chemical Properties

White powder

Uses

substrate for laminarinase and other glucanases

Uses

Cavity size is the major determinant as to which cyclodextrin is used in complexation. The cavity diameter of β-cyclodextrins or β-glucopyranose unit compounds is well-suited for use with molecules the size of hormones, vitamins and many compounds frequently used in tissue and cell culture applications. For this reason, β-cyclodextrin is most commonly used as a complexing agent. It is used to increase the solubility of non-polar substances such as fatty acids, lipids, vitamins and cholesterol for use in cell culture applications. Methyl-β-cyclodextrin is used to remove cholesterol from cultured cells and is employed to remove lipid rafts.

Uses

Methyl-β-cyclodextrin is a cholesterol-removing agent mainly used for lipid raft disruption. It may also be used for detergent removal from protein-lipid-detergent ternary mixture to produce 2D membrane protein crystals due to its high solubility and affinity for detergents generally used in membrane protein chemistry.

General Description

Methyl-β-cyclodextrin is a small cyclic heptasaccharide.

Biochem/physiol Actions

Methyl-β-cyclodextrin participates in increasing the permeability of cells. It also plays a role in depolymerizing the actin cytoskeleton in cells. Methyl-β-cyclodextrin is involved in attracting cholesterol from the plasma. It participates in activating extracellular receptor kinase in certain cells.

beta-Cyclodextrin methyl ethers Preparation Products And Raw materials

Raw materials

Preparation Products

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beta-Cyclodextrin methyl ethers Suppliers

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View Lastest Price from beta-Cyclodextrin methyl ethers manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Methyl-Beta-Cyclodextrin 128446-36-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%min
Supply Ability
500kg
Release date
2024-06-28
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Methyl Beta Cyclodextrin 128446-36-6
Price
US $120.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-08
Shandong Deshang Chemical Co., Ltd.
Product
beta-Cyclodextrin methyl ethers 128446-36-6
Price
US $10.00-7.00/kg
Min. Order
1kg
Purity
99.99%
Supply Ability
10 tons
Release date
2024-06-14

128446-36-6, beta-Cyclodextrin methyl ethersRelated Search:

Tribenuron methyl Thiophanate-methyl gamma-Cyclodextrin POLY(METHYLSILSESQUIOXANE) 2,6-Lutidine CYCLODEXTRIN beta-Cyclodextrin hydrate Methyl salicylate Methyl acetate Kresoxim-methyl 2,6-DI-O-METHYL-BETA-CYCLODEXTRIN METSULFURON METHYL 2-Hydroxypropyl-β-cyclodextrin β-Cyclodextrin Calcium lactate Methyl METHYL BETA-D-GLUCOPYRANOSIDE alpha-D-Methylglucoside

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