ChemicalBook > CAS DataBase List > 2-Propylpiperidine

2-Propylpiperidine

Product Name
2-Propylpiperidine
CAS No.
3238-60-6
Chemical Name
2-Propylpiperidine
Synonyms
CONIINE;DL-CONIINE;rac-coniine;(+/-)CONINE;CONIINE, DL-;2-PROPYLPIPERIDINE;2-PRIOPYLPIPERIDINE;2-N-PROPYLPIPERIDINE;(R)-2-Propylpiperidine;(2R)-2-Propylpiperidine
CBNumber
CB5700543
Molecular Formula
C8H17N
Formula Weight
127.23
MOL File
3238-60-6.mol
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2-Propylpiperidine Property

Melting point:
-2℃
Boiling point:
56-60 °C(Press: 13 Torr)
Density 
0.85 g/mL at 25 °C(lit.)
storage temp. 
Sealed in dry,2-8°C
form 
liquid
pka
pK1:11.24(+1) (25°C,μ=0.5)
color 
, clear colorless to yellow-green
CAS DataBase Reference
3238-60-6(CAS DataBase Reference)
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Safety

Hazard Codes 
T
Risk Statements 
23/24/25-40
Safety Statements 
22-36/37/39-45
RIDADR 
UN 2810 6.1/PG 2
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2933399990
Toxicity
Piperidine alkaloid obtained from poison hemlock, Conium maculatum. Alkaline, steam volatile liquid (b.p. 167_x0003_C), mousy odor. Darkens and polymerizes in air. It can be reduced at high temperature with HI to n-octane and oxidized to pyridine-1-carboxylic acid. The hydrochloride is used as an antispasmodic.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H301Toxic if swalloed

H311Toxic in contact with skin

H331Toxic if inhaled

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P311Call a POISON CENTER or doctor/physician.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P363Wash contaminated clothing before reuse.

P370+P378In case of fire: Use … for extinction.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B523530
Product name
2-Propylpiperidine
Packaging
100mg
Price
$700
Updated
2021/12/16
Matrix Scientific
Product number
041235
Product name
2-n-Propylpiperidine
Purity
97%
Packaging
500mg
Price
$100
Updated
2021/12/16
Matrix Scientific
Product number
041235
Product name
2-n-Propylpiperidine
Purity
97%
Packaging
1g
Price
$154
Updated
2021/12/16
SynQuest Laboratories
Product number
3H31-1-AM
Product name
2-n-Propylpiperidine
Purity
97%
Packaging
2g
Price
$295
Updated
2021/12/16
Matrix Scientific
Product number
041235
Product name
2-n-Propylpiperidine
Purity
97%
Packaging
5g
Price
$462
Updated
2021/12/16
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2-Propylpiperidine Chemical Properties,Usage,Production

Chemical Properties

Colorless liquid; darkens on exposure tolight and air; polymerizes; boils at 166°C(330.8°F); melts at -2°C (28.4°F); alkaline, pKa 3.1; density 0.845 at 20°C (68°F);slightly soluble in water and chloroform,readily soluble in most organic solvents.

Uses

Coniine is present in all parts of the plantpoison hemlock (Conium maculatum). It isthe first alkaloid to be synthesized and structure determined. Because of its high toxicity,its clinical application is very limited.

Synthesis Reference(s)

Tetrahedron Letters, 26, p. 4633, 1985 DOI: 10.1016/S0040-4039(00)98771-9

Health Hazard

Coniine is a highly toxic alkaloid. Thetoxic symptoms from ingestion are weakness,drowsiness, nausea, vomiting, muscle contraction, and labored breathing. A high dosecan cause convulsions, cyanosis, asphyxia,and death. Chronic ingestion of coniine produced adverse reproductive effects and spe cific developmental abnormalities in cattles.LD50 value, oral (mice): 100 mg/kg.

2-Propylpiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

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