(S)-2-PIPERIDINONE-6-CARBOXYLIC ACID Property

Melting point:

129-134 °C

Boiling point:

437.0±38.0 °C(Predicted)

Density 

1.286±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

Aqueous Acid (Sparingly, Heated, Sonicated), DMSO (Slightly, Heated)

form 

Solid

pka

3.59±0.20(Predicted)

color 

White to Pale Brown

InChIKey

FZXCPFJMYOQZCA-BYPYZUCNSA-N

CAS DataBase Reference

34622-39-4(CAS DataBase Reference)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26

WGK Germany 

2

HS Code 

2933790090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

(S)-2-PIPERIDINONE-6-CARBOXYLIC ACID Chemical Properties,Usage,Production

Uses

6-Oxo-L-pipecolic Acid is an intermediate in the synthesis of metabolites of lysine developed during aging and in diabetic patients.

Uses

(S)-6-Oxo-2-piperidinecarboxylic acid can be used as a reactant to synthesize:

• Functionalized β-lactam N-heterocycles via carboxymethylproline synthase catalyzed cyclization reactions. Pro-(S)-C⁵ branched [4.3.1] aza-amide bicycles as potential inhibitors for FK506-binding proteins.
• Ethyl (S)-2-(6-oxopiperidin-2-yl)acetate, which is reduced using LiBH₄ to produce optically pure hydroxymethyl lactams.