ChemicalBook > CAS DataBase List > 4-METHOXY-3-NITROACETOPHENONE

4-METHOXY-3-NITROACETOPHENONE

Product Name
4-METHOXY-3-NITROACETOPHENONE
CAS No.
6277-38-9
Chemical Name
4-METHOXY-3-NITROACETOPHENONE
Synonyms
ASISCHEM D29251;Einecs 228-476-7;4-METHOXY-3-NITROACETOPHENONE;3-NITRO-4-METHOXYACETOPHENONE;4'-Methoxy-3'-nitroacetophenone;1-(4-METHOXY-3-NITROPHENYL)ETHANONE;4'-Methoxy-3'-nitroacetophenone 98%;4'-Methoxy-3'-nitroacetophenone, 98+%;1-(4-METHOXY-3-NITROPHENYL)ETHAN-1-ONE;Ethanone, 1-(4-methoxy-3-nitrophenyl)-
CBNumber
CB5702714
Molecular Formula
C9H9NO4
Formula Weight
195.17
MOL File
6277-38-9.mol
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4-METHOXY-3-NITROACETOPHENONE Property

Melting point:
97-100 °C(lit.)
Boiling point:
315.1±22.0 °C(Predicted)
Density 
1.244±0.06 g/cm3(Predicted)
storage temp. 
Store at room temperature
form 
powder to crystal
color 
White to Yellow to Green
BRN 
646069
InChI
1S/C9H9NO4/c1-6(11)7-3-4-9(14-2)8(5-7)10(12)13/h3-5H,1-2H3
InChIKey
VXLKYQQBEPCMJE-UHFFFAOYSA-N
SMILES
COc1ccc(cc1[N+]([O-])=O)C(C)=O
CAS DataBase Reference
6277-38-9(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2914790090
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
553654
Product name
4′-Methoxy-3′-nitroacetophenone
Purity
97%
Packaging
10g
Price
$92.9
Updated
2026/03/19
TCI Chemical
Product number
M2811
Product name
4'-Methoxy-3'-nitroacetophenone
Purity
>98.0%(GC)
Packaging
5g
Price
$44
Updated
2026/03/19
TRC
Product number
M265778
Product name
1-(4-Methoxy-3-nitrophenyl)ethanone
Packaging
500mg
Price
$75
Updated
2021/12/16
Apolloscientific
Product number
OR26752
Product name
4'-Methoxy-3'-nitroacetophenone
Purity
98%
Packaging
10g
Price
$90
Updated
2021/12/16
AK Scientific
Product number
J55554
Product name
4′-Methoxy-3′-nitroacetophenone
Packaging
100g
Price
$380
Updated
2021/12/16
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4-METHOXY-3-NITROACETOPHENONE Chemical Properties,Usage,Production

Uses

4′-Methoxy-3′-nitroacetophenone may be used to synthesize dimethylamino compound, via W2 Raney nickel catalyzed reductive methylation.

Preparation

Preparation by reaction of acetyl chloride with 2-nitroanisole in the presence of aluminium chloride,
in nitrobenzene at 0° ;
in carbon disulfide.

General Description

4′-Methoxy-3′-nitroacetophenone can be synthesized from p-methoxyacetophenone via nitration.

4-METHOXY-3-NITROACETOPHENONE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-METHOXY-3-NITROACETOPHENONE Suppliers

Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
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saleschina@alfa-asia.com
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China
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Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
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China
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Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
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Syntechem Co.,Ltd
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Fax
E-Mail Inquiry
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info@syntechem.com
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China
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TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
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TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
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TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
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Shanghai Run-Biotech Co., Ltd.
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021-57171705 13817537615
Fax
QQ3095748324
Email
sales@run-biotech.com
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China
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Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39999
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Shanghai Na Qian Chemical Technology Co. Ltd.
Tel
13598610367 13598610367
Fax
QQ:2468833170
Email
2841375912@qq.com
Country
China
ProdList
2787
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6277-38-9, 4-METHOXY-3-NITROACETOPHENONERelated Search:


  • ASISCHEM D29251
  • 1-(4-METHOXY-3-NITROPHENYL)ETHAN-1-ONE
  • 1-(4-METHOXY-3-NITROPHENYL)ETHANONE
  • 3-NITRO-4-METHOXYACETOPHENONE
  • 4-METHOXY-3-NITROACETOPHENONE
  • Einecs 228-476-7
  • 4'-Methoxy-3'-nitroacetophenone 98%
  • 1-(4-Methoxy-3-nitrophenyl)ethan-1-one, 4-Acetyl-2-nitroanisole
  • 4'-Methoxy-3'-nitroacetophenone, 98+%
  • JRH-08503, 1-(4-Methoxy-3-nitrophenyl)ethanone, 97%
  • Ethanone, 1-(4-methoxy-3-nitrophenyl)-
  • 4'-Methoxy-3'-nitroacetophenone
  • 4′-Methoxy-3′-nitroacetophenone, CAS 6277-38-9
  • 1-(4-Methoxy-3-nitrophenyl)ethan-1-one - [M93409]
  • 6277-38-9
  • CH3OC6H3NO2COCH3
  • CH3OO2NC6H3COCH3
  • Organic Building Blocks
  • Ketones
  • Carbonyl Compounds
  • C9
  • Building Blocks
  • Aromatic Acetophenones & Derivatives (substituted)
  • C9
  • Carbonyl Compounds
  • Ketones