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2-AMINO-1-BUTANOL

Product Name
2-AMINO-1-BUTANOL
CAS No.
96-20-8
Chemical Name
2-AMINO-1-BUTANOL
Synonyms
AB;2-Aminobutan-1-ol;Butanol-2-amine;1-Butanol, 2-amino-;>=98.0% (GC);2-AMINOBUTANOLE;2-amino-1-butano;2-AMINO-1-BUTANOL;3-Bromocumene >2-AMinol-1-butanol
CBNumber
CB5706631
Molecular Formula
C4H11NO
Formula Weight
89.14
MOL File
96-20-8.mol
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2-AMINO-1-BUTANOL Property

Melting point:
-2 °C (lit.)
Boiling point:
176-178 °C (lit.)
Density 
0.943 g/mL at 25 °C (lit.)
vapor pressure 
58.1Pa at 25℃
refractive index 
n20/D 1.452
Flash point:
184 °F
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
Water Solubility 
Completely miscible in water
solubility 
Chloroform (Sparingly), Methanol (Slightly)
pka
12.88±0.10(Predicted)
form 
Liquid
color 
Clear
Sensitive 
Air Sensitive & Hygroscopic
Merck 
14,427
BRN 
1098274
LogP
-0.45 at 20℃
CAS DataBase Reference
96-20-8(CAS DataBase Reference)
EPA Substance Registry System
1-Butanol, 2-amino- (96-20-8)
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Safety

Hazard Codes 
C
Risk Statements 
34-50-22
Safety Statements 
26-36/37/39-45-61
RIDADR 
UN 2735 8/PG 3
WGK Germany 
2
RTECS 
EK9625000
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29221990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A43804
Product name
2-Amino-1-butanol
Purity
97%
Packaging
100ml
Price
$63.7
Updated
2025/07/31
Sigma-Aldrich
Product number
1020008
Product name
Aminobutanol
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
500mg
Price
$1040
Updated
2025/07/31
TCI Chemical
Product number
A0684
Product name
DL-2-Amino-1-butanol
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$22
Updated
2025/07/31
TCI Chemical
Product number
A0684
Product name
DL-2-Amino-1-butanol
Purity
>98.0%(GC)(T)
Packaging
500g
Price
$114
Updated
2025/07/31
Sigma-Aldrich
Product number
A43804
Product name
2-Amino-1-butanol
Purity
97%
Packaging
500ml
Price
$136
Updated
2025/07/31
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2-AMINO-1-BUTANOL Chemical Properties,Usage,Production

Chemical Properties

clear liquid

Uses

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Uses

Emulsifying agent (in soap form) for oils, fats, and waxes; absorbent for acidic gases; organic syn- thesis.

Application

2-amino- 1-butanol is a precursor for the antituberculotic ethambuto.

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Synthesis

2835-81-6

96-20-8

22621-37-0

The general procedure for the synthesis of 2-amino-1-butanol and compounds (CAS:22621-37-0) from DL-2-aminobutyric acid is as follows: Preparation of (+) - 2-amino-1-butanol (Example 9): 1. 1.8 g of L-2-aminobutyric acid obtained in Example 5 was dispersed in 30 mL of ethanol. 2. Dry hydrogen chloride gas was passed into this dispersed system until the L-2-aminobutyric acid was completely dissolved to form a homogeneous solution. 3. The resulting solution was refluxed for 4 hours. 4. Upon completion of the reaction, the reaction mixture was cooled and the ethanol was subsequently evaporated under reduced pressure. 5. The residue was dissolved in cooled ammonia and subsequently extracted with ether. 6. 6. The ether extracts were combined and dried with magnesium sulfate. 7. After drying, distillation was carried out under reduced pressure to collect the fraction with a boiling point of 66°C-67°C/18 mmHg to give 2.0 g of ethyl L-2-aminobutyrate in 90% yield. 8. The product had a specific optical rotation of 0.01%. 8. The specific optical rotation of the product was (α)D27 = +17.8°±1° (C=5.6, ethanol).

Purification Methods

They are purified by shaking with solid NaOH, filtering and distilling through a short column. The oxalate of the racemate has m 176o. They are strong bases and should be stored under N2 in the absence of CO2. The enantiomers have [] 20 ±12.5o (c 2, EtOH). [Johnson & Degering J Org Chem 8 7 1943, Nagao et al. J Org Chem 51 2392 1986, Santaniello et al. J Chem Soc, Perkin Trans 1 919 1985, Beilstein 4 H 291, 4 IV 1705.]

References

[1] Patent: US3979457, 1976, A

2-AMINO-1-BUTANOL Preparation Products And Raw materials

Raw materials

2,2-DICHLOROBUTANE (R)-(-)-2-Amino-1-butanol

Preparation Products

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2-AMINO-1-BUTANOL Suppliers

Americas 1 Australia 2 Austria 1 Belgium 3 Canada 1 China 210 Czech 1 Europe 3 France 2 Germany 5 India 15 Japan 4 Norway 1 Poland 2 Spain 1 Switzerland 1 The Netherlands 2 Ukraine 2 United Kingdom 13 United States 52 Global 322
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
TCI Chemical Trading Co., Ltd.
Tel
--
Fax
--
Email
sales@tci-chemical-trading.com
Country
Japan
ProdList
597
Advantage
58
K. Sakai & Co., Ltd.
Tel
--
Fax
--
Email
em@ksakai.co.jp
Country
Japan
ProdList
957
Advantage
58
FUJIFILM Wako Pure Chemical Corporation
Tel
--
Fax
--
Email
ffwk-cservice@fujifilm.com
Country
Japan
ProdList
6222
Advantage
58
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View Lastest Price from 2-AMINO-1-BUTANOL manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
2-AMINO-1-BUTANOL 96-20-8
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-19
Henan Fengda Chemical Co., Ltd
Product
2-AMINO-1-BUTANOL 96-20-8
Price
US $10.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-28
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-AMINO-1-BUTANOL 96-20-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

96-20-8, 2-AMINO-1-BUTANOLRelated Search:

1,2-Dichloroethane l-Ethambutol Ethambutol Related Compound A (15 mg) ((2R,2'S)-2,2'-[ethane-1,2-diylbis(azanediyl)]dibutan-1-ol) Ethambutol dihydrochloride 2-Amino-2-methyl-1-propanol tert-Butyl carbamate Ethambutol Tropine (R)-(-)-2-Amino-1-butanol 1-Butanol 1,1,1-TRIFLUORO-4-([2-(1H-INDOL-3-YL)ETHYL]AMINO)-2-BUTANOL (S)-(+)-2-Amino-1-butanol

  • (n)-2-amino-1-butanol
  • Aminobutanol (500 mg)
  • (§1)-2-Amino-1-butanol, 97%
  • (7bR,8aS)-1,2,8,8aβ-Tetrahydro-2-[1H-indol-2-ylcarbonyl]-7-methylcyclopropa[c]pyrrolo[3,2-e]indol-4(5H)-one
  • (7bR,8aS)-1,2,8,8aβ-Tetrahydro-7-methyl-2-[(1H-indol-2-yl)carbonyl]cyclopropa[c]pyrrolo[3,2-e]indol-4(5H)-one
  • (8S)-3,7-Dihydro-8H-8β,8aβ-methano-1-methyl-6-[(1H-indol-2-yl)carbonyl]benzo[1,2-b:4,3-b']dipyrrol-4(6H)-one
  • 2-AMinol-1-butanol
  • 2-AMINO-1-BUTANOL FOR SYNTHESIS
  • 1-Hydroxybutan-2-amine, 2-Amino-1-hydroxybutane
  • >=98.0% (GC)
  • (+/-)-2-AMINO-1-BUTANOL
  • 2-AMINO-1-BUTANOL
  • LABOTEST-BB LT01409643
  • Butanol-2-amine
  • 1-(Hydroxymethyl)propylamine
  • 1-Hydroxy-2-butylamine
  • 2-amino-1-butano
  • 2-Amino-1-hydroxybutane
  • 2-amino-butan-1-ol
  • 2-Aminobutan-1-ol
  • 2-Aminobutyl alcohol
  • 2-Amino-n-butyl alcohol
  • AB
  • 1-Butanol, 2-amino-
  • Ethambutol EP Impurity A
  • 2-Amino-1-butanol (AB)
  • 1,4-Bis(2-hydroxyethyl)benzene &gt
  • Bis(4-cyanophenyl) Ether &gt
  • 3,5-Dimethyl-3-heptene (cis- and trans- mixture)&gt
  • erythro-3-Methoxy-2-methyl-4-phenylbutyricAcid&gt
  • 3,9-Bis(2-cyanoethyl)-2,4,8,10-tetraoxaspiro[5.5]undecane &gt
  • 1,2-Dibromo-3-chloropropane &gt
  • IsopropylCinnamate&gt
  • 2-Chloroacetamide &gt
  • 2,12-Dichlorocyclododecanone&gt
  • DL-2-Amino-1-butanol &gt
  • 2-Chlorobenzophenone&gt
  • 3,5-Bis(tert-butylthio)benzyl Acetate &gt
  • N,N-Bis(3-chlorobenzyl)amine &gt
  • 2-Bromobenzenethiol&gt
  • 1,2-Epoxycyclopentadecane &gt
  • 3,5-Bis(tert-butylthio)benzyl Bromide &gt
  • 4-tert-Butyl-4'-iodobiphenyl &gt
  • 1,4-Bis(3-methoxyphenoxy)benzene &gt
  • 11H-Benzo[b]fluoren-11-one &gt
  • 3-Methyl-2-butenyl Benzoate &gt
  • Cyclohexyltrichlorosilane &gt
  • N-tert-Butyl-2-methoxyethylamine &gt
  • Butyl Anthranilate &gt
  • Butyl Glycidyl Ether &gt
  • 4-Bromo-o-cresol &gt
  • 3-Methyl-1-phenyl-2-butanone &gt
  • Amylamine(mixtureofisomers)&gt
  • 2,6-Bis(hydroxymethyl)-p-cresol &gt
  • 3-Bromocumene &gt
  • 2-[4-(Hydroxymethyl)-2-nitrophenoxy]ethanol&gt
  • 3-Chloro-2-fluoroaniline &gt
  • 4-Bromo-2,6-dimethylphenol &gt