ChemicalBook > CAS DataBase List > 2-ACETAMIDO-5-BROMOTHIAZOLE

2-ACETAMIDO-5-BROMOTHIAZOLE

Product Name
2-ACETAMIDO-5-BROMOTHIAZOLE
CAS No.
7336-54-1
Chemical Name
2-ACETAMIDO-5-BROMOTHIAZOLE
Synonyms
AKOS BB-9164;2-ACETAMIDO-5-BROMOTHIAZOLE;2-ACETYLAMINO-5-BROMOTHIAZOLE;2-Acetamido-5-bromo-1,3-thiazole;N-(5-BROMO-THIAZOL-2-YL)-ACETAMIDE;Acetamide, N-(5-bromo-2-thiazolyl)-
CBNumber
CB5711619
Molecular Formula
C5H5BrN2OS
Formula Weight
221.07
MOL File
7336-54-1.mol
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2-ACETAMIDO-5-BROMOTHIAZOLE Property

Melting point:
229-231 °C
Density 
1.820±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
pka
9.03±0.50(Predicted)
form 
solid
color 
Yellow
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Safety

Hazard Codes 
Xi
HS Code 
2934100090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A143810
Product name
2-Acetamido-5-bromothiazole
Packaging
500mg
Price
$70
Updated
2021/12/16
TRC
Product number
A143810
Product name
2-Acetamido-5-bromothiazole
Packaging
1g
Price
$105
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA66897
Product name
2-Acetamido-5-bromothiazole
Packaging
5G
Price
$125
Updated
2021/12/16
Matrix Scientific
Product number
069541
Product name
2-Acetylamino-5-bromothiazole
Purity
98%
Packaging
1g
Price
$171
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA66897
Product name
2-Acetamido-5-bromothiazole
Packaging
10g
Price
$225
Updated
2021/12/16
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2-ACETAMIDO-5-BROMOTHIAZOLE Chemical Properties,Usage,Production

Synthesis

3034-22-8

7336-54-1

A. Preparation of 2-acetamido-5-bromothiazole Acetic anhydride (11 mL) was added slowly and dropwise to a mixed solution of dichloromethane (100 mL) and pyridine (60 mL) of 2-amino-5-bromothiazole (22.3 g, 85.9 mmol) while maintaining stirring. The reaction mixture was stirred at room temperature for 2.5 hours and then continued to stir for 4 hours to ensure complete reaction. Upon completion of the reaction, most of the solvent was removed by distillation under reduced pressure. The residue was washed sequentially with ethyl acetate and dilute aqueous hydrochloric acid to remove unreacted feedstock and by-products. The organic phase was subsequently washed to neutrality with water and dried with anhydrous magnesium sulfate. The dried organic solution was concentrated to give a crude product. The crude product was ground with ether, filtered, washed with ether and dried to give 2-acetamido-5-bromothiazole solid (15.1 g, 80% yield, molecular formula C5H5BrN2OS, mass spectrum m/e 222 (M + H)+).

References

[1] Patent: US6407124, 2002, B1
[2] Helvetica Chimica Acta, 1945, vol. 28, p. 985,988
[3] Svensk Kemisk Tidskrift, 1945, vol. 57, p. 229,232

2-ACETAMIDO-5-BROMOTHIAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-ACETAMIDO-5-BROMOTHIAZOLE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2-Acetamido-5-bromo-1,3-thiazole 7336-54-1
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2025-08-21
Career Henan Chemical Co
Product
2-ACETAMIDO-5-BROMOTHIAZOLE 7336-54-1
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-09