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3'-DC CEP

Product Name
3'-DC CEP
CAS No.
157327-96-3
Chemical Name
3'-DC CEP
Synonyms
3'-dC;3'-DC CEP;3'-dC-CE Phosphoramidite;3’-dC(Bz)-2’-phosphoramidite;3'-dC(Bz)-2'-phosphor amidite;N6-Benzoyl-5'-O-DMT-3'-deoxycytidine 2'-CE phosphoramidite;N6-Benzoyl-3'-deoxy-5'-O-DMT-cytidine 2'-CE phosphoramidite;N4-Benzoyl-5’-O-(4,4-dimethoxytrityl)-3’-deoxycytidine-2’-CED-phosphoramidite;5'-Dimethoxytrityl-N-benzoyl-3'-deoxyCytidine,2'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite;4-N-benzoyl-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)cytidine 2-cyanoethyl N,N-diisopropylphosphoramidite
CBNumber
CB5718421
Molecular Formula
C46H52N5O8P
Formula Weight
833.91
MOL File
157327-96-3.mol
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3'-DC CEP Property

solubility 
DMSO: Sparingly Soluble: 1-10 mg/ml
Ethanol: Sparingly Soluble: 1-10 mg/ml
pka
8.58±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
NUC0005048
Product name
N-BENZOYL-5'-O-[BIS-(4-METHOXYPHENYL)PHENYLMETHYL]-3'-DEOXY-2'-[2-CYANOETHYLBIS-(1-METHYLETHYL)PHOSPHORAMIDITE]CYTIDINE
Purity
95.00%
Packaging
5MG
Price
$496.24
Updated
2021/12/16
Biosynth Carbosynth
Product number
PB32726
Product name
N6-Benzoyl-3'-deoxy-5'-O-DMT-cytidine 2'-CE phosphoramidite
Packaging
1g
Price
$4700
Updated
2021/12/16
AK Scientific
Product number
8515CV
Product name
N-[1-[(2R,3R,5S)-5-[[Bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
Packaging
1g
Price
$6395
Updated
2021/12/16
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3'-DC CEP Chemical Properties,Usage,Production

Uses

3’-dC(Bz)-2’-phosphor amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] ERANDE N, GUNJAL A D, FERNANDES M, et al. Synthesis and structural studies of S-type/N-type-locked/frozen nucleoside analogues and their incorporation in RNA-selective, nuclease resistant 2′–5′ linked oligonucleotides†[J]. Organic & Biomolecular Chemistry, 2012, 5: 746-757. DOI: 10.1039/c2ob26762d

3'-DC CEP Preparation Products And Raw materials

Raw materials

Preparation Products

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3'-DC CEP Suppliers

China 19 United Kingdom 1 United States 6 Global 26
BOC Sciences
Tel
16314854226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
9713
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BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19552
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58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58
Protheragen-ING
Tel
+16313385890
Email
info@protheragen-ing.com
Country
United States
ProdList
3868
Advantage
58
United States Biological
Tel
--
Fax
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Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Berry & Associates, Inc.
Tel
--
Fax
--
Email
orders@berryassoc.com
Country
United States
ProdList
535
Advantage
66

157327-96-3, 3'-DC CEPRelated Search:

N4-BENZOYL-5'-O-(DIMETHOXYTRITYL)-3'-DEOXYCYTIDINE 3'-DC CEP N4-BENZOYL-3'-DEOXYCYTIDINE

  • 3'-DC CEP
  • N6-Benzoyl-5'-O-DMT-3'-deoxycytidine 2'-CE phosphoramidite
  • N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-deoxycytidine 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
  • 4-N-benzoyl-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)cytidine 2-cyanoethyl N,N-diisopropylphosphoramidite
  • 3'-dC(Bz)-2'-phosphor amidite
  • N6-Benzoyl-3'-deoxy-5'-O-DMT-cytidine 2'-CE phosphoramidite
  • Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-deoxy-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)
  • N4-Benzoyl-5’-O-(4,4-dimethoxytrityl)-3’-deoxycytidine-2’-CED-phosphoramidite
  • 5'-Dimethoxytrityl-N-benzoyl-3'-deoxyCytidine,2'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
  • 3'-dC-CE Phosphoramidite
  • 3'-dC
  • (2R,3R,5S)-2-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
  • 3’-dC(Bz)-2’-phosphoramidite
  • 157327-96-3