ChemicalBook > CAS DataBase List > MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

Product Name: MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
CAS No.: 1599440-25-1
Chemical Name: MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
Synonyms: Liner;MC-GGFG-Glycolic acid;(S)-10-benzyl-23-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-6,9,12,15,18-pentaoxo-3-oxa-5,8,11,14,17-pentaazatricosanoic acid;(S)-10-benzyl-23-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-6,9,12,15,18-pentaoxo-3-oxa-5,8,11,14,17-pentaazatricosan-1-oic acid;EX-A4328;Suc-GGFG-Acid;Schembl17003584;MC-Gly-Gly-Phe-Gly-Dxd;MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH;2,4-Dichlorobenzyl Alcohol Impurity 26
CBNumber: CB57247539
Molecular Formula: C28H36N6O10
Formula Weight: 616.62
MOL File: 1599440-25-1.mol

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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH Property

Boiling point:: 1137.9±65.0 °C(Predicted)
Density: 1.341±0.06 g/cm3(Predicted)
storage temp.: 2-8°C, sealed storage, away from moisture
solubility: DMSO : 120 mg/mL (194.61 mM; Need ultrasonic)
form: Solid
pka: 3.20±0.10(Predicted)
color: White to off-white
InChIKey: SODPQQOBNODMSG-FQEVSTJZSA-N
SMILES: [C@@H](NC(=O)CNC(=O)CNC(=O)CCCCCN1C(C=CC1=O)=O)(C(=O)NCC(=O)NCOCC(=O)O)CC1C=CC=CC=1

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Hazard and Precautionary Statements (GHS)

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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH Chemical Properties,Usage,Production

Description

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Uses

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

References

[1] Masuda, Takeshi, et al. Conjugué anticorps-médicament. WO2014057687A1.

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: MC-GGFG-Glycolic acid 1599440-25-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

1599440-25-1, MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOHRelated Search:

Glycinamide,N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy) methyl] -

EX-A4328

Mc-Gly-Gly-Phe-2-((2-aminoacetamido)methoxy)acetic acid

Schembl17003584

MC-GGFG-Glycolic acid

(S)-10-benzyl-23-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-6,9,12,15,18-pentaoxo-3-oxa-5,8,11,14,17-pentaazatricosanoic acid

MC-Gly-Gly-Phe-Gly-Dxd

(S)-10-benzyl-23-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-6,9,12,15,18-pentaoxo-3-oxa-5,8,11,14,17-pentaazatricosan-1-oic acid

Liner

Mal-Gly-Gly-L-Phe-N-[(carboxymethoxy)methyl]Glycinamide

Suc-GGFG-Acid

MC-GGFG-Glycolic acid MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

2-[(2-[(2S)-2-(2-(2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)acetamido)acetamido)-3-phenylpropanamido]acetamido)methoxy]acetic acid

2,4-Dichlorobenzyl Alcohol Impurity 26

1599440-25-1

C28H36N6O10

ADC LINKER

ADCs

ADC-Linkers