6-AMINO-2-METHYL-2H-INDAZOLE
Appearance- Product Name
- 6-AMINO-2-METHYL-2H-INDAZOLE
- CAS No.
- 50593-30-1
- Chemical Name
- 6-AMINO-2-METHYL-2H-INDAZOLE
- Synonyms
- 2-Methyl-2H-indazol-6-amine;6-AMINO-2-METHYL-2H-INDAZOLE;2-Methyl-2H-indazole-6-amine;6-aMine-2-Methyl-2H-indazole;6-Amino-2-methyl-2H-indaz...;2H-Indazol-6-amine, 2-methyl-;6-AMINO-2-METHYLBENZO[C]PYRAZOLE
- CBNumber
- CB5733477
- Molecular Formula
- C8H9N3
- Formula Weight
- 147.18
- MOL File
- 50593-30-1.mol
6-AMINO-2-METHYL-2H-INDAZOLE Property
- Melting point:
- 148-150
- Boiling point:
- 354.8±15.0 °C(Predicted)
- Density
- 1.27±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 3.31±0.10(Predicted)
- form
- Crystalline Powder
- color
- Yellow to green
- InChI
- InChI=1S/C8H9N3/c1-11-5-6-2-3-7(9)4-8(6)10-11/h2-5H,9H2,1H3
- InChIKey
- MHCWLERQNFATHZ-UHFFFAOYSA-N
- SMILES
- N1=C2C(C=CC(N)=C2)=CN1C
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 29339980
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- M321333
- Product name
- 2-Methyl-2H-indazol-6-amine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR3688
- Product name
- 6-Amino-2-methyl-2H-indazole
- Packaging
- 250mg
- Price
- $58
- Updated
- 2021/12/16
- Product number
- 3H30-1-L4
- Product name
- 6-Amino-2-methyl-2H-indazole
- Packaging
- 250mg
- Price
- $64
- Updated
- 2021/12/16
- Product number
- 046583
- Product name
- 2-Methyl-2H-indazol-6-amine
- Purity
- >95%
- Packaging
- 500mg
- Price
- $111
- Updated
- 2021/12/16
- Product number
- 046583
- Product name
- 2-Methyl-2H-indazol-6-amine
- Purity
- >95%
- Packaging
- 1g
- Price
- $170
- Updated
- 2021/12/16
6-AMINO-2-METHYL-2H-INDAZOLE Chemical Properties,Usage,Production
Appearance
Brown crystalline powder
Uses
2-Methyl-2H-indazol-6-ylamine is a research chemical that can be used as a pharmaceutical intermediate.
Synthesis
6850-22-2
50593-30-1
General procedure for the synthesis of 2-methyl-6-amino-2H-indazole from 2-methyl-6-nitro-2H-indazole: 10% palladium-carbon catalyst (51.7% in water, 1 g) was added to a solution of 2-methyl-6-nitro-2H-indazole (7.50 g, 40 mmol) in ethanol (150 ml). The reaction mixture was placed under hydrogen atmosphere and stirred at room temperature for 12 hours. After completion of the reaction, the catalyst was removed by filtration and the catalyst residue was washed with ethanol. The filtrate and washings were combined and the solvent was removed by distillation under reduced pressure to afford the target product 2-methyl-6-amino-2H-indazole as a light beige solid (6.05 g, 95.0% yield).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 4, p. 1108 - 1110
[2] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1988, p. 403 - 409
[3] Khimiya Geterotsiklicheskikh Soedinenii, 1988, vol. 24, # 4, p. 491 - 498
[4] Journal of Chemical Research, Miniprint, 1990, # 11, p. 2601 - 2615
[5] Heterocycles, 1995, vol. 41, # 3, p. 487 - 496
6-AMINO-2-METHYL-2H-INDAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
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