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DEXLOXIGLUMIDE

Product Name
DEXLOXIGLUMIDE
CAS No.
119817-90-2
Chemical Name
DEXLOXIGLUMIDE
Synonyms
DEXLOXIGLUMIDE;-5-((3-methoxypropyl);-4-(3,4-Dichlorobenzamido);(R)-4-(3,4-DichlorobenzaMido)-5-((3-Methoxypropyl)(pentyl)aMino)-5-oxopentanoic acid;(R)-4-(3,4-Dichlorobenzoylamino)-5-[(3-methoxypropyl)pentylamino]-5-oxopentanoic acid;(4r)-4-[(3,4-dichlorobenzoyl)amino]-5-[3-methoxypropyl(pentyl)amino]-5-oxopentanoic Acid;pentanoic acid, 4-[(3,4-dichlorobenzoyl)amino]-5-[(3-methoxypropyl)pentylamino]-5-oxo-, (4r)-;(4R)-4-[[(3,4-dichlorophenyl)-oxomethyl]amino]-5-[3-methoxypropyl(pentyl)amino]-5-oxopentanoic acid
CBNumber
CB5743470
Molecular Formula
C21H30Cl2N2O5
Formula Weight
461.38
MOL File
119817-90-2.mol
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DEXLOXIGLUMIDE Property

Boiling point:
632.2±55.0 °C(Predicted)
Density 
1.233±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: 50 mg/ml, sonicated
form 
A solid
pka
4.48(at 25℃)
color 
White to off-white
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-36-37/39
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0054881
Product name
Dexloxiglumide
Purity
98.25%
Packaging
1mg
Price
$50
Updated
2021/12/16
ChemScene
Product number
CS-0054881
Product name
Dexloxiglumide
Purity
98.25%
Packaging
5mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-0054881
Product name
Dexloxiglumide
Purity
98.25%
Packaging
10mg
Price
$250
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0000402
Product name
DEXLOXIGLUMIDE
Purity
95.00%
Packaging
25MG
Price
$692.23
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0000402
Product name
DEXLOXIGLUMIDE
Purity
95.00%
Packaging
1G
Price
$2152.5
Updated
2021/12/16
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DEXLOXIGLUMIDE Chemical Properties,Usage,Production

Uses

Dexloxiglumide is a selective cholecystokinin type A (CCKA) receptor antagonist[1]. Dexloxiglumide, the active enantiomer of Loxiglumide, inhibits smooth muscle cell contractions induced by cholecystokinin-octapeptide (CCK-8)[2].

Definition

ChEBI: Dexloxiglumide is a glutamic acid derivative.

References

[1] Scarpignato C, et al. Effect of dexloxiglumide and spiroglumide, two new CCK-receptor antagonists, on gastric emptying and secretion in the rat: evaluation of their receptor selectivity in vivo. Aliment Pharmacol Ther. 1996 Jun;10(3):411-9. DOI:10.1111/j.0953-0673.1996.00411.x
[2] Maselli MA, et al. CCK1 receptor antagonist, dexloxiglumide: effects on human isolated gallbladder. Potential clinical applications. Minerva Gastroenterol Dietol. 2003 Sep;49(3):211-6. PMID:16484960

DEXLOXIGLUMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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119817-90-2, DEXLOXIGLUMIDERelated Search:


  • DEXLOXIGLUMIDE
  • (R)-4-(3,4-DichlorobenzaMido)-5-((3-Methoxypropyl)(pentyl)aMino)-5-oxopentanoic acid
  • pentanoic acid, 4-[(3,4-dichlorobenzoyl)amino]-5-[(3-methoxypropyl)pentylamino]-5-oxo-, (4r)-
  • -4-(3,4-Dichlorobenzamido)
  • -5-((3-methoxypropyl)
  • (R)-4-(3,4-Dichlorobenzoylamino)-5-[(3-methoxypropyl)pentylamino]-5-oxopentanoic acid
  • (4R)-4-[[(3,4-dichlorophenyl)-oxomethyl]amino]-5-[3-methoxypropyl(pentyl)amino]-5-oxopentanoic acid
  • (4r)-4-[(3,4-dichlorobenzoyl)amino]-5-[3-methoxypropyl(pentyl)amino]-5-oxopentanoic Acid
  • 119817-90-2
  • C17H24NO4Cl