(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL

Uses

Product Name: (R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL
CAS No.: 142128-92-5
Chemical Name: (R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL
Synonyms: SF120008;(S)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAP&;2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL;2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHALENE;(S)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL;(R)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL;(S)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl>(S)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthalene;(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL;(S)-(-)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl
CBNumber: CB5744068
Molecular Formula: C24H22O4
Formula Weight: 374.43
MOL File: 142128-92-5.mol

More

Less

(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL Property

Melting point:: 92-96 °C(lit.)
alpha: -85° (c 0.22, CHCl3)
Boiling point:: 477.8±45.0 °C(Predicted)
Density: 1.182±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: soluble in Toluene
form: Powder
color: white

More

Less

Safety

Hazard Codes: Xi,N
Risk Statements: 41-50/53
Safety Statements: 26-39-60-61-36/39-25
RIDADR: UN 3077 9/PG 3
WGK Germany: 3
HS Code: 2909.30.6000

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H318Causes serious eye damage

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: B3203
Product name: (S)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl
Purity: >98.0%(GC)
Packaging: 1g
Price: $132
Updated: 2025/07/31

TCI Chemical

Product number: B3203
Product name: (S)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl
Purity: >98.0%(GC)
Packaging: 5g
Price: $457
Updated: 2025/07/31

Strem Chemicals

Product number: 08-0171
Product name: (S)-(-)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl, 98%
Packaging: 250mg
Price: $66
Updated: 2024/03/01

Strem Chemicals

Product number: 08-0171
Product name: (S)-(-)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl, 98%
Packaging: 1g
Price: $193
Updated: 2024/03/01

Strem Chemicals

Product number: 08-0171
Product name: (S)-(-)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl, 98%
Packaging: 5g
Price: $646
Updated: 2024/03/01

More

Less

(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL Chemical Properties,Usage,Production

Uses

Starting material for the preparation of a variety of 3,3'-substituted binaphthols.

Synthesis

18531-99-2

107-30-2

74292-20-9

GENERAL STEPS: Example 1 Preparation of (S)-3,3'-difluoro-1,1'-binaphthyl-2,2'-diol (3) Synthesis of (S)-2,2'-bis(methoxymethoxy)-1,1'-binaphthyl (4): a solution was formed by dissolving (R)-1,1'-binaphthyl-2,2'-diol (30 g, 0.10 mol) in THF (200 mL). This solution was slowly added to a stirred 60 wt% sodium hydride (NaH) slurry (10.48 g, 0.26 mol, dissolved in THF 100 mL) at 0-10 °C. The reaction temperature was kept below 10 °C and the mixture was stirred for 1 hour. Subsequently, chloromethyl methyl ether (MOMCl) (20.25 g, 0.25 mol) was added dropwise with controlled drop acceleration to maintain the temperature below 10 °C. After addition, the reaction mixture was continued to be stirred at 0-5°C for 1 hour. Upon completion of the reaction, water (100 mL) was added slowly to quench the reaction. The organic phase was separated and the aqueous phase was extracted with ethyl acetate (EtOAc, 2 x 250 mL). The organic layers were combined, washed with water (200 mL) and concentrated to give a light yellow solid. This solid was slurried in a 10:1 (v/v) hexane/EtOAc mixture, the solid was collected by filtration and dried under reduced pressure to give Product 4 as a white solid. Yield: 38.5 g, 98% yield.

References

[1] Journal of the American Chemical Society, 2003, vol. 125, # 17, p. 5139 - 5151
[2] Chemistry - A European Journal, 2009, vol. 15, # 43, p. 11450 - 11453
[3] Molecules, 2012, vol. 17, # 5, p. 5626 - 5650
[4] Angewandte Chemie - International Edition, 2015, vol. 54, # 49, p. 14748 - 14752
[5] Angew. Chem., 2015, vol. 127, # 49, p. 14961 - 14965,5

(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL Suppliers

Americas 1 China 60 Europe 1 Germany 2 India 2 Japan 2 Switzerland 1 The Netherlands 1 United Kingdom 1 United States 10 Global 81

Tianjin Derchemist Science & Technology Co., Ltd.

Tel: 22-58627059 13920586291
Fax: 022-58620305
Email: zdcomcon@126.com
Country: China
ProdList: 3829
Advantage: 50

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 7471
Advantage: 65

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

TCI Europe

Tel: 320-37350700
Fax: +32 (0)37350701
Email: sales@tcieurope.eu
Country: Europe
ProdList: 23671
Advantage: 75

TCI AMERICA

Tel: 800-4238616
Fax: +1-888-520-1075 / +1-503-283-1987
Email: sales@tciamerica.com
Country: Americas
ProdList: 23653
Advantage: 75

HBCChem, Inc.

Tel: +1-510-219-6317
Fax: +1-650-486-1361
Email: sales@hbcchem.com
Country: United States
ProdList: 10648
Advantage: 60

More

Less

View Lastest Price from (R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL manufacturers

Career Henan Chemical Co

Product: (R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL 142128-92-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-08

142128-92-5, (R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYLRelated Search:

(S)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl, 99%e.e.

(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHALENE

(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL

(R)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL

(S)-(-)-2,2'-BIS(METHOXYMETHOXY)-1,1-BINAPHTHALENE

(S)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL

2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHALENE

2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL

(S)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAP&

(S)-(-)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl,98%

2-(methoxymethoxy)-1-[2-(methoxymethoxy)-1-naphthyl]naphthalene

SF120008

(S)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl&gt

1,1'-Binaphthalene, 2,2'-bis(methoxymethoxy)-, (1S)-

(S)-(-)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl

(S)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthalene

142128-92-5

Chiral Catalysts, Ligands, and Reagents

Asymmetric Synthesis

BINOLs

Privileged Ligands

BINOL Series

Chiral Oxygen