ChemicalBook > CAS DataBase List > 3-Hydroxy-1,8-naphthalic anhydride

3-Hydroxy-1,8-naphthalic anhydride

Product Name: 3-Hydroxy-1,8-naphthalic anhydride
CAS No.: 23204-36-6
Chemical Name: 3-Hydroxy-1,8-naphthalic anhydride
Synonyms: 5-hydroxy-1H,3H-benzo[de]isochromene-1,3-dione;SKL057;Albb-005281;hydroxynaphthalicanhydride;3-Hydroxynaphthalic anhydride;3-HYDROXY-1,8-NAPHTHALIC ANHYDRIDE;3-hydroxy-1,8-naphthalic acid anhydride;5-HYDROXY-BENZO[DE]ISOCHROMENE-1,3-DIONE;3-Hydroxy-1,8-naphthalenedicarboxylic anhydride;3-Hydroxynaphthalene-1,8-dicarboxylic anhydride
CBNumber: CB5749346
Molecular Formula: C12H6O4
Formula Weight: 214.17
MOL File: 23204-36-6.mol

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3-Hydroxy-1,8-naphthalic anhydride Property

Melting point:: 281 °C
Boiling point:: 509.4±33.0 °C(Predicted)
Density: 1.585±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: soluble in Dimethylformamide
form: powder to crystal
pka: 7.93±0.20(Predicted)
color: Light yellow to Yellow
InChI: InChI=1S/C12H6O4/c13-7-4-6-2-1-3-8-10(6)9(5-7)12(15)16-11(8)14/h1-5,13H
InChIKey: FKVNZFAMXGMPOU-UHFFFAOYSA-N
SMILES: C1(=O)OC(=O)C2=CC(O)=CC3=C2C1=CC=C3

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
HS Code: 2917.39.7000
HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical

Product number: H0278
Product name: 3-Hydroxy-1,8-naphthalic Anhydride
Purity: >98.0%(T)
Packaging: 5g
Price: $384
Updated: 2025/07/31

TRC

Product number: H953573
Product name: 5-Hydroxy-1H,3H-benzo[de]isochromene-1,3-dione
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 037062
Product name: 5-Hydroxy-1H,3H-benzo[de]isochromene-1,3-dione
Packaging: 500mg
Price: $69
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0027192
Product name: 5-HYDROXY-BENZO[DE]ISOCHROMENE-1,3-DIONE
Purity: 95.00%
Packaging: 0.5G
Price: $682
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0027192
Product name: 5-HYDROXY-BENZO[DE]ISOCHROMENE-1,3-DIONE
Purity: 95.00%
Packaging: 1G
Price: $750.75
Updated: 2021/12/16

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3-Hydroxy-1,8-naphthalic anhydride Chemical Properties,Usage,Production

Uses

Used as pharmaceutical intermediates for RD.

Synthesis

23204-38-8

23204-36-6

General procedure for the synthesis of 5-hydroxybenzo[de]isochroman-1,3-dione from 5-amino-1H,3H-benzo[DE]isochroman-1,3-dione: Compound 3 (8 mmol, 1.7 g) was placed in a three-necked flask, and 432 mL of aqueous sulfuric acid solution (sulfuric acid to water in a ratio of 1:5, by volume) was added and the reaction system was cooled down to 0 °C. Subsequently, sodium nitrite (12 mmol, 0.81 g) was slowly added and stirred continuously at 0 °C for 1 hour. After completion of the reaction, the reaction system was gradually warmed to room temperature and then stirred at 120 °C for 12 hours. At the end of the reaction, the reaction mixture was cooled to room temperature, filtered through a Kiriyama funnel and the filter cake was washed with water and dried. The crude product was recrystallized with chloroform to afford the target product 5-hydroxybenzo[de]isochromene-1,3-dione.

References

[1] Patent: JP2018/39777, 2018, A. Location in patent: Paragraph 0115; 0119; 0120
[2] Journal of Photochemistry and Photobiology A: Chemistry, 2015, vol. 303-304, p. 28 - 35

3-Hydroxy-1,8-naphthalic anhydride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-Hydroxy-1,8-naphthalic anhydride manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 3-HYDROXY-1,8-NAPHTHALIC ANHYDRIDE 23204-36-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-22

Henan Fengda Chemical Co., Ltd

Product: 3-Hydroxy-1,8-naphthalic anhydride 23204-36-6
Price: US $10.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-28

23204-36-6, 3-Hydroxy-1,8-naphthalic anhydrideRelated Search:

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3-Hydroxy-1,8-naphthalenedicarboxylic anhydride

hydroxynaphthalicanhydride

3-HYDROXY-1,8-NAPHTHALIC ANHYDRIDE

5-HYDROXY-BENZO[DE]ISOCHROMENE-1,3-DIONE

3-hydroxy-1,8-naphthalic acid anhydride

5-hydroxy-1H,3H-benzo[de]isochromene-1,3-dione

3-Hydroxy-1,8-naphthalenedicarboxylic acid=anhydride ester

3-Hydroxynaphthalene-1,8-dicarboxylic anhydride

Albb-005281

3-Hydroxynaphthalic anhydride

1H,3H-Naphtho[1,8-cd]pyran-1,3-dione, 5-hydroxy-

SKL057

23204-36-6

23204-36-4

C12H6O4

Intermediates of Dyes and Pigments