4-FORMYL-N,N-DIMETHYL-BENZAMIDE
- Product Name
- 4-FORMYL-N,N-DIMETHYL-BENZAMIDE
- CAS No.
- 58287-76-6
- Chemical Name
- 4-FORMYL-N,N-DIMETHYL-BENZAMIDE
- Synonyms
- 130912;4-FORMYL-N,N-DIMETHYL-BENZAMIDE;Benzamide, 4-formyl-N,N-dimethyl-;4-(N,N-DIMETHYLCARBAMOYL)BENZALDEHYDE
- CBNumber
- CB5749997
- Molecular Formula
- C10H11NO2
- Formula Weight
- 177.2
- MOL File
- Mol file
4-FORMYL-N,N-DIMETHYL-BENZAMIDE Property
- Boiling point:
- 345.6±25.0 °C(Predicted)
- Density
- 1.133±0.06 g/cm3(Predicted)
- storage temp.
- Store at Room Tem.
- pka
- -1.66±0.70(Predicted)
- form
- solid
- Appearance
- white solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 8410CR
- Product name
- 4-Formyl-n,n-dimethylbenzamide
- Packaging
- 1g
- Price
- $502
- Updated
- 2021/12/16
- Product number
- 8410CR
- Product name
- 4-Formyl-n,n-dimethylbenzamide
- Packaging
- 2.5g
- Price
- $888
- Updated
- 2021/12/16
- Product number
- CD12058690
- Product name
- 4-Formyl-N,N-dimethylbenzamide
- Purity
- 95+%
- Packaging
- 1g
- Price
- $583
- Updated
- 2021/12/16
- Product number
- 6566848
- Product name
- 4-Formyl-N,N-dimethyl-benzamide
- Purity
- 95%
- Packaging
- 5G
- Price
- $700
- Updated
- 2021/12/16
- Product number
- 1004126
- Product name
- MC002524:4-Formyl-N,N-dimethyl-benzamide
- Purity
- 96
- Packaging
- 5G
- Price
- $1068
- Updated
- 2021/12/16
4-FORMYL-N,N-DIMETHYL-BENZAMIDE Chemical Properties,Usage,Production
Synthesis
619-66-9
68-12-2
58287-76-6
Example 101 Synthesis of 4-formyl-N,N-dimethylbenzamide: To an anhydrous dichloromethane (8 mL) suspension of 4-formylbenzoic acid (4.00 g, 26.7 mmol), thionyl chloride (2.92 g, 40.0 mmol) and N,N-dimethylformamide (0.6 mL) were added sequentially. The reaction was carried out dropwise at room temperature under nitrogen protection. Subsequently, the reaction mixture was heated to reflux for 2 hours. Upon completion of the reaction, it was cooled to room temperature and then slowly added dropwise to 33% aqueous dimethylamine solution (10.5 mL, 72 mmol) in an ice-water bath for 15 minutes. After the dropwise addition, the reaction mixture was continued to be stirred at the same temperature for 1 hour. At the end of the reaction, the solvent was removed by distillation under reduced pressure. The crude product was purified by silica gel column chromatography to afford the title compound (2.5 g, 53% yield) as a yellow solid. ^1H-NMR (400 MHz, DMSO-d6) δ (ppm): 2.86 (s, 3H), 3.30 (s, 3H), 7.60 (d, J = 7.6 Hz, 2H), 7.95 (d, J = 7.6 Hz, 2H), 10.04 (s, 1H); LC-MS (ESI) m/z: 178 (M + 1)+.
References
[1] Patent: WO2011/130661, 2011, A1. Location in patent: Page/Page column 153
4-FORMYL-N,N-DIMETHYL-BENZAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
4-FORMYL-N,N-DIMETHYL-BENZAMIDE Suppliers
- Tel
- 15366165407
- 1018682665@qq.com
- Country
- China
- ProdList
- 82
- Advantage
- 58
- Tel
- 0512-63009836 18994340901
- Fax
- 0512-63006936
- helen@struchem.com
- Country
- China
- ProdList
- 3979
- Advantage
- 60
- Tel
- 177-54423994 17754423994
- Fax
- QQ:2853530913
- 2853530910@QQ.com
- Country
- China
- ProdList
- 8000
- Advantage
- 62
- Tel
- 19906241957
- Fax
- -
- 1557216087@qq.com
- Country
- China
- ProdList
- 1853
- Advantage
- 55
- Tel
- 025-66113011 19370895928
- Fax
- (7)02557626880
- qzhang@aikonchem.com
- Country
- China
- ProdList
- 15393
- Advantage
- 58
- Tel
- 18021193238
- Fax
- QQ：534936027
- 534936027@qq.com
- Country
- China
- ProdList
- 363
- Advantage
- 58
- Tel
- +8613580539051
- joe@yuhengpharm.com
- Country
- CHINA
- ProdList
- 21142
- Advantage
- 58
- Tel
- 19963477321; 19963477321
- Fax
- QQ:2041275825
- 2041275825@qq.com
- Country
- China
- ProdList
- 1483
- Advantage
- 58
- Tel
- 13564747822
- Fax
- QQ774046800
- 669027880@qq.com
- Country
- China
- ProdList
- 1055
- Advantage
- 58
- Tel
- 027-027-16602739303 16602739303
- 673003916@qq.com
- Country
- China
- ProdList
- 4114
- Advantage
- 58