ChemicalBook > CAS DataBase List > 2,4-Difluorobenzonitrile

2,4-Difluorobenzonitrile

Product Name
2,4-Difluorobenzonitrile
CAS No.
3939-09-1
Chemical Name
2,4-Difluorobenzonitrile
Synonyms
0/1/39;CASNO: 3939-9-1;2,4-Difluorobenzonit;2-difluorobenzotrile;4-Difluorobenzonitrile;2，4-difluorobenzotrile;2,4-Difuorobenzonitrile;2,4-DIFLUOROBENZONITRILE;2,4-difluorobenzonilyile;2,4-Difluorobenzonitrile,98%
CBNumber
CB5754551
Molecular Formula
C7H3F2N
Formula Weight
139.1
MOL File
3939-09-1.mol
More
Less

2,4-Difluorobenzonitrile Property

Melting point:
47-49 °C (lit.)
Boiling point:
189°C
Density 
1.246
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
Crystalline
color 
White to Almost white
BRN 
1940316
InChI
InChI=1S/C7H3F2N/c8-6-2-1-5(4-10)7(9)3-6/h1-3H
InChIKey
LJFDXXUKKMEQKE-UHFFFAOYSA-N
SMILES
C(#N)C1=CC=C(F)C=C1F
CAS DataBase Reference
3939-09-1(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xn,T,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-37/39-36/37/39-36/37
RIDADR 
UN3439
WGK Germany 
3
Hazard Note 
Toxic
HazardClass 
6.1
HS Code 
29269090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
264326
Product name
2,4-Difluorobenzonitrile
Purity
97%
Packaging
25g
Price
$33.66
Updated
2024/03/01
Sigma-Aldrich
Product number
264326
Product name
2,4-Difluorobenzonitrile
Purity
97%
Packaging
5g
Price
$25
Updated
2023/06/20
TCI Chemical
Product number
D1826
Product name
2,4-Difluorobenzonitrile
Purity
>98.0%(GC)
Packaging
5g
Price
$29
Updated
2025/07/31
TCI Chemical
Product number
D1826
Product name
2,4-Difluorobenzonitrile
Purity
>98.0%(GC)
Packaging
25g
Price
$83
Updated
2025/07/31
TRC
Product number
D445515
Product name
2,4-Difluorobenzonitrile
Packaging
25g
Price
$140
Updated
2021/12/16
More
Less

2,4-Difluorobenzonitrile Chemical Properties,Usage,Production

Chemical Properties

white crystalline solid

Uses

2,4-Difluorobenzonitrile has been used in the synthesis of:

  • 2-methylsulfonyl-4-fluorobenzylamine
  • fluoro-3-amino-1,2-benzisoxazoles

General Description

2,4-Difluorobenzonitrile undergoes polycondensation with Bisphenol A and matrix-assisted laser desorption/time-of-flight mass spectra revealed a quantitative formation of cyclic oligoethers and polyethers.

Synthesis

85118-02-1

3939-09-1

General procedure for the synthesis of 2,4-difluorobenzonitrile from 2,4-difluorobenzamide: In a 250 mL three-necked flask, 2,4-difluorobenzamide (23.0 g, 146.2 mmol) was dissolved in dry N,N-dimethylformamide (80 mL), and cooled to -15°C. The reaction was continued for 0.5 h at room temperature. Phosphorus oxychloride (112.1 g, 730.9 mmol) was slowly added dropwise and the reaction was kept for 0.5 h. The reaction was then continued for 7 h at room temperature. Upon completion of the reaction, the reaction solution was slowly poured into a vessel containing ice to induce precipitation of solids. Finally, 17.0 g of 2,4-difluorobenzonitrile was obtained in 83.4% yield.

References

[1] Patent: CN106854165, 2017, A. Location in patent: Paragraph 0104; 0105; 0136; 0137

2,4-Difluorobenzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2,4-Difluorobenzonitrile Suppliers

Americas 1 Belgium 1 Canada 1 China 277 Europe 4 France 1 Germany 3 India 7 Italy 1 Japan 4 Jordan 1 Slovakia 1 South Korea 1 Switzerland 1 The Netherlands 1 Ukraine 1 United Kingdom 20 United States 35 Global 361
Taizhou Jun Rui Import and Export Co., Ltd.
Tel
0576-88808091 13958565781
Fax
0576-88808091
Email
janney.liu@groundfortune.com
Country
China
ProdList
61
Advantage
55
Cangzhou Kangrui Medical Technology Co., LTD
Tel
18632776803
Email
355803330@qq.com
Country
China
ProdList
630
Advantage
58
Shandong Baiyang Biotechnology Co., Ltd
Tel
0533-13505335043 13505335043
Email
jinqiu9966@163.com
Country
China
ProdList
74
Advantage
58
Cangzhou Enke Pharma Tech Co.,ltd.
Tel
0317-5106596 15533709196
Email
1154424302@qq.com
Country
China
ProdList
2262
Advantage
58
Xintai Huabao Chemical Technology Co., LTD
Tel
0538-6378866 13854877258
Email
934928173@qq.com
Country
China
ProdList
8
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9883
Advantage
59
Shanghai Harvest Chemical Industrial Co., Ltd.
Tel
021-31038972,31038973 17321035817
Fax
+86-21-51385350
Email
sales@harvest-chem.com
Country
China
ProdList
2816
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16077
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Nanjing Lynsci Chemical Co., Ltd
Tel
+86-025-83208253 +86-13851694729
Fax
0086-25-83208253
Email
layefe@163.com
Country
China
ProdList
231
Advantage
62
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Aemon Chemical
Tel
0086-755-86198205
Email
acinfo@aemonchem.com
Country
China
ProdList
1931
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
4000
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
SuZhou ShiYa Biopharmaceuticals, Inc.
Tel
86(512)5235 8471 17715136450
Fax
86(512)5235 6881
Email
sales@shiyabiopharm.com
Country
China
ProdList
4169
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9546
Advantage
55
Bsisun HK Imoprt And Export Company Limited
Tel
+86-18068513926
Fax
0086-519-85153711
Country
China
ProdList
1277
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3930
Advantage
58
Beijing Universal Century Technology Co., Ltd.
Tel
400-8706899
Fax
400-8706899
Email
hysj_bj.com
Country
China
ProdList
3583
Advantage
55
Nanjing ShengSai Chemical Co., Ltd.
Tel
025-85205967 13951876367
Fax
025-85205967
Email
shengsaichem@163.com
Country
China
ProdList
818
Advantage
58
Shanghai Hekang Biotechnology Co., Ltd.
Tel
18939837085
Fax
2880152141(QQ)
Email
youchemicals@gmail.com
Country
China
ProdList
1839
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9979
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Country
China
ProdList
2930
Advantage
58
Zhengzhou HongSheng Pharmaceutical Co., Ltd.
Tel
0371-0371-13526885213 15637198702
Fax
0371-63709726
Email
hsyykjchem@163.com
Country
China
ProdList
3853
Advantage
58
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5872
Advantage
58
More
Less

View Lastest Price from 2,4-Difluorobenzonitrile manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2,4-Difluorobenzonitrile 3939-09-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
2000ton
Release date
2024-05-11
Qiuxian Baitai New Material Co., LTD
Product
good quality 2,4-Dif 4-(Trifluoromethoxy) 3939-09-1
Price
US $11.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
500ton/Month
Release date
2021-07-29
Career Henan Chemical Co
Product
2,4-Difluorobenzonitrile 3939-09-1
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
Customized
Release date
2018-12-14

3939-09-1, 2,4-DifluorobenzonitrileRelated Search:

2,6-Difluorobenzonitrile 3,4-Difluorobenzonitrile Tetrachloroterephthalonitrile 3-Nitrophthalonitrile 2,4-Difluorophenylhydrazine BISMERTHIAZOL Ethyl nicotinate Benzonitrile

  • 2,4-DIFLUOROBENZONITRILE
  • 2，4-difluorobenzotrile
  • 2,4-Difluorobenzonitrile,98%
  • 2,4-difluorobenzonilyile
  • 2-difluorobenzotrile
  • 2,4-Difluorobenzonitrile 98%
  • 2,4-Difluorobenzenecarbonitrile
  • 2,4-DIFLUOROBENZONITRILE 97+%
  • CASNO: 3939-9-1
  • 2,4-Difluorobenzonit
  • 4-Difluorobenzonitrile
  • 2,4-Difuorobenzonitrile ,99.5%
  • [(2,4-difluorophenyl)Methylidyne]azanidyl
  • 2,4-Difuorobenzonitrile
  • 2,4-Difluorobenzonitrile &gt
  • good quality 2,4-Dif 4-(Trifluoromethoxy)
  • 0/1/39
  • 3939-09-1
  • 3939-9-1
  • 744974
  • 744-97-4
  • 939-09-1
  • Cyanides/Nitriles
  • Organic Building Blocks
  • Nitrogen Compounds
  • C6 to C7
  • Building Blocks
  • Aromatic Nitriles
  • Nitrile
  • Boron, Nitrile, Thio,& TM-Cpds
  • Fluorobenzene Series
  • Fluorine Compounds
  • Nitriles
  • C6 to C7
  • Cyanides/Nitriles
  • Nitrogen Compounds
  • OLED