[TYR0] GASTRIC INHIBITORY PEPTIDE (23-42), HUMAN

Product Name: [TYR0] GASTRIC INHIBITORY PEPTIDE (23-42), HUMAN
CAS No.: 121765-67-1
Chemical Name: [TYR0] GASTRIC INHIBITORY PEPTIDE (23-42), HUMAN
Synonyms: [TYR0] GASTRIC INHIBITORY PEPTIDE (23-42), HUMAN;[Tyr22] Gastric Inhibitory Peptide (22-42), human;TYR-VAL-ASN-TRP-LEU-LEU-ALA-GLN-LYS-GLY-LYS-LYS-ASN-ASP-TRP-LYS-HIS-ASN-ILE-THR-GLN;[Tyr0] Gastric Inhibitory Peptide (23-42), human: [Tyr22] Gastric Inhibitory Peptide (22-42), human;TYR-VAL-ASN-TRP-LEU-LEU-ALA-GLN-LYS-GLY-LYS-LYS-ASN-ASP-TRP-LYS-HIS-ASN-ILE-THR-GLN: YVNWLLAQKGKKNDWKHNITQ
CBNumber: CB5754809
Molecular Formula: C119H182N34O31
Formula Weight: 2584.93
MOL File: Mol file

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Hazard and Precautionary Statements (GHS)

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[TYR0] GASTRIC INHIBITORY PEPTIDE (23-42), HUMAN Chemical Properties,Usage,Production

Uses

[Tyr0] Gastric Inhibitory Peptide (23-42), human, a glucose-dependent insulinotropic polypeptide (GIP), is a weak inhibitor of gastric acid secretion that also stimulates insulin secretion. [Tyr0] Gastric Inhibitory Peptide (23-42), human can be used in diabetes, obesity research[1][2].

in vivo

GIPR^-/- mice have higher blood glucose levels and impaired initial insulin response after oral glucose loading. In GIPR^+/+ mice, a high-fat diet did not increase postprandial intake blood glucose levels, whereas it significantly increased in GIPR^-/- mice^[2].

References

[1] LaPelusa A, et al. Biochemistry, Bombesin[M]//StatPearls [Internet]. StatPearls Publishing, 2021.
[2] K Miyawaki, et al. Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout mice. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14843-7. DOI:10.1073/pnas.96.26.14843

[TYR0] GASTRIC INHIBITORY PEPTIDE (23-42), HUMAN Preparation Products And Raw materials

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Preparation Products

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[TYR0] GASTRIC INHIBITORY PEPTIDE (23-42), HUMAN Suppliers

China 14 United States 1 Global 15

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121765-67-1, [TYR0] GASTRIC INHIBITORY PEPTIDE (23-42), HUMANRelated Search:

(TYR0)-C-TYPE NATRIURETIC PEPTIDE (32-53) (HUMAN, PORCINE, RAT) H-TYR-HIS-LYS-THR-ASP-SER-PHE-VAL-GLY-LEU-MET-NH2 (TYR0)-KALIURETIC PEPTIDE (HUMAN) (TYR0)-FIBRINOPEPTIDE A H-TYR-ALA-VAL-SER-GLU-HIS-GLN-LEU-LEU-HIS-ASP-LYS-GLY-LYS-SER-ILE-GLN-ASP-LEU-ARG-ARG-ARG-PHE-PHE-LEU-HIS-HIS-LEU-ILE-ALA-GLU-ILE-HIS-THR-ALA-GLU-ILE-ARG-ALA-THR-SER-OH (TYR0)-HYPERCALCEMIA OF MALIGNANCY FACTOR (1-34) (HUMAN, RAT) (TYR0)-STRESSCOPIN-RELATED PEPTIDE (HUMAN) (TYR0)-UROCORTIN (RAT) (TYR0)-STRESSCOPIN (HUMAN) H-TYR-ASP-MET-HIS-ASP-PHE-PHE-VAL-GLY-LEU-MET-NH2

TYR-VAL-ASN-TRP-LEU-LEU-ALA-GLN-LYS-GLY-LYS-LYS-ASN-ASP-TRP-LYS-HIS-ASN-ILE-THR-GLN

[Tyr0] Gastric Inhibitory Peptide (23-42), human: [Tyr22] Gastric Inhibitory Peptide (22-42), human

TYR-VAL-ASN-TRP-LEU-LEU-ALA-GLN-LYS-GLY-LYS-LYS-ASN-ASP-TRP-LYS-HIS-ASN-ILE-THR-GLN: YVNWLLAQKGKKNDWKHNITQ

[Tyr22] Gastric Inhibitory Peptide (22-42), human

[TYR0] GASTRIC INHIBITORY PEPTIDE (23-42), HUMAN

121765-67-1