4-SULFONIC ACID-L-PHENYLALANINE
- Product Name
- 4-SULFONIC ACID-L-PHENYLALANINE
- CAS No.
- 34023-49-9
- Chemical Name
- 4-SULFONIC ACID-L-PHENYLALANINE
- Synonyms
- S12000;H-S-PHE(4-SO3H)-OH;L-Phenylalanine, 4-sulfo-;-2-Amino-3-(4-sulfophenyl);P-SULFONIC ACID-L-PHENYLALANINE;4-SULFONIC ACID-L-PHENYLALANINE;(S)-PHENYLALANINE-4-SULFONIC ACID;(S)-4-(SULFONIC ACID)-PHENYLALANINE;(S)-2-Amino-3-(4-sulfophenyl)propanoic acid
- CBNumber
- CB5759091
- Molecular Formula
- C9H11NO5S
- Formula Weight
- 245.25
- MOL File
- 34023-49-9.mol
4-SULFONIC ACID-L-PHENYLALANINE Property
- Density
- 1.530±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- -0.61±0.50(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- AS113292
- Product name
- (S)-2-Amino-3-(4-sulfophenyl)propanoic acid
- Purity
- 97+% ee
- Packaging
- 25mg
- Price
- $162
- Updated
- 2021/12/16
- Product number
- AS113292
- Product name
- (S)-2-Amino-3-(4-sulfophenyl)propanoic acid
- Purity
- 97+% ee
- Packaging
- 100mg
- Price
- $300
- Updated
- 2021/12/16
- Product number
- AS113292
- Product name
- (S)-2-Amino-3-(4-sulfophenyl)propanoic acid
- Purity
- 97+% ee
- Packaging
- 250mg
- Price
- $520
- Updated
- 2021/12/16
- Product number
- AS113292
- Product name
- (S)-2-Amino-3-(4-sulfophenyl)propanoic acid
- Purity
- 97+% ee
- Packaging
- 1g
- Price
- $1167
- Updated
- 2021/12/16
- Product number
- CM252328
- Product name
- (S)-2-Amino-3-(4-sulfophenyl)propanoicacid
- Purity
- 95%
- Packaging
- 1g
- Price
- $795
- Updated
- 2021/12/16
4-SULFONIC ACID-L-PHENYLALANINE Chemical Properties,Usage,Production
Synthesis
63-91-2
34023-49-9
General procedure for the synthesis of (S)-2-amino-3-(4-sulfophenyl)propionic acid from L-phenylalanine: a mixture of 2.8 g of chlorosulfonic acid (24 mmol) and 1.95 g of L-phenylalanine (12 mmol) was added to a 100 mL round-bottomed flask, and the reaction was cooled in an ice-water bath for 12 hours. Upon completion of the reaction, ice water was slowly added to the reaction solution until a deep pink precipitate appeared, followed by rapid filtration through a Büchner funnel. The pink colored filtrate obtained was dissolved in distilled water and heated in an oil bath at 60°C. After the crystals were completely dissolved, 0.5 g of activated carbon was added for decolorization and the filtrate was collected after filtration. Isopropanol was added to the filtrate for crystallization. After crystallization, the crystals were washed with water, dried and filtered, and finally the solvent was removed by vacuum evaporation. Finally, 2.6 g of white solid product was obtained with 87% yield (Figure 1C).
References
[1] Letters in Drug Design and Discovery, 2015, vol. 12, # 6, p. 466 - 470
[2] Helvetica Chimica Acta, 1983, vol. 66, # 5, p. 1355 - 1365
[3] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 8, p. 2680 - 2683
4-SULFONIC ACID-L-PHENYLALANINE Preparation Products And Raw materials
Raw materials
Preparation Products
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