TUFTSIN

ChemicalBook > CAS DataBase List > TUFTSIN

Product Name: TUFTSIN
CAS No.: 9063-57-4
Chemical Name: TUFTSIN
Synonyms: Taftsin;TUFTSIN;Tuftsin(3TFA);THR-LYS-PRO-ARG;TUFTSIN 2ACOH 4H2O;H-Thr-Lys-Pro-Arg-OH;THR-LYS-PRO-ARG 2ACOH 4H2O;L-Thr-L-Lys-L-Pro-L-Arg-OH;Tuftsin hydrate acetate salt;Tuftsin Tuftsin acetate salt hydrate
CBNumber: CB5769625
Molecular Formula: C21H40N8O6
Formula Weight: 500.59
MOL File: 9063-57-4.mol

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TUFTSIN Property

Density: 1.48±0.1 g/cm3(Predicted)
storage temp.: −20°C
pka: 3.60±0.21(Predicted)
Water Solubility: Water : ≥ 160 mg/mL (319.62 mM)
Sequence: H-Thr-Lys-Pro-Arg-OH

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-7100
Product name: Tuftsin
Purity: 98.40%
Packaging: 5mg
Price: $60
Updated: 2021/12/16

ChemScene

Product number: CS-7100
Product name: Tuftsin
Purity: 98.40%
Packaging: 10mg
Price: $84
Updated: 2021/12/16

ChemScene

Product number: CS-7100
Product name: Tuftsin
Purity: 98.40%
Packaging: 25mg
Price: $114
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0003512
Product name: TUFTSIN
Purity: 95.00%
Packaging: 5MG
Price: $570
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0003512
Product name: TUFTSIN
Purity: 95.00%
Packaging: 10MG
Price: $689
Updated: 2021/12/16

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TUFTSIN Chemical Properties,Usage,Production

Uses

Tuftsin is an immunostimulatory agent that induces bactericidal and tumoricidal activity by promoting phagocytosis, antigen presentation and cell migration.

Biological Activity

Tuftsin is a tetrapeptide and a macrophage/microglia activator.

in vitro

Tuftsin is a tetrapeptide, Thr-Lys-Pro-Arg, which resides in the Fc-domain of the heavy chain of immunoglobulin G. Tuftsin possesses a broad spectrum of activities related primarily to the immune system function and exerts on phagocytic cells, notably on macrophages. Tuftsin's capacity to augment cellular activation is mediated by specific receptors that are identified, characterized, and recently isolated from rabbit peritoneal granulocytes. Tuftsin, a macrophage/microglial activator, dramatically improves the clinical course of experimental autoimmune encephalomyelitis (EAE), a well-established animal model for MS. Tuftsin administration correlates with upregulation of the immunosuppressive Helper-2 Tcell (Th2) cytokine transcription factor GATA-3. Tuftsin promotes phagocytic activity for cells of monocytic origin, such as neutrophils, macrophages and microglia, all of which are thought to express Tuftsin receptors.

target

Human Endogenous Metabolite

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TUFTSIN Preparation Products And Raw materials

Raw materials

Preparation Products

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TUFTSIN Suppliers

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View Lastest Price from TUFTSIN manufacturers

Career Henan Chemical Co

Product: TUFTSIN 9063-57-4
Price: US $1.00/g
Min. Order: 1g
Purity: ≥98%
Supply Ability: g/kg/Ton
Release date: 2020-03-05

9063-57-4, TUFTSINRelated Search:

(3,4-DEHYDRO-PRO3)-TUFTSIN (LYS(Z)2)-TUFTSIN TUFTSIN P-AMINOPHENYLACETYL-THR-LYS-PRO-ARG TUFTSIN ACETATE SALT

TUFTSIN

TUFTSIN 2ACOH 4H2O

THR-LYS-PRO-ARG

THR-LYS-PRO-ARG 2ACOH 4H2O

Tuftsin hydrate acetate salt

L-Thr-L-Lys-L-Pro-L-Arg-OH

Taftsin

Tuftsin Tuftsin acetate salt hydrate

H-Thr-Lys-Pro-Arg-OH

Tuftsin Tuftsin acetate salt hydrate, ≥97% (HPLC)

Tuftsin(3TFA)

L-Arginine, L-threonyl-L-lysyl-L-prolyl-

9063-57-4

C21H40N8O6

Peptide