MEVASTATIN, SODIUM SALT

MEVASTATIN, SODIUM SALT Property

storage temp. 

-20°C

solubility 

ethanol: 20mg/mL
DMSO: 30mg/mL

form 

solid

color 

white

Safety

WGK Germany 

WGK 1

Storage Class

11 - Combustible Solids

Hazard and Precautionary Statements (GHS)

MEVASTATIN, SODIUM SALT Chemical Properties,Usage,Production

Uses

Carboxylate form of Mevastatin that is active in whole cells and in cell-free assays.
Carboxylate form of Mevastatin that is active in whole cells and in cell-free assays. Mevastatin is an antibiotic that acts as a potent inhibitor of HMG-CoA reductase. Suppresses Ras farnesylation and inhibits myoblast fusion. Causes cell cycle arrest in late G₁ phase. Mevastatin may also induce bone morphogenic protein-2 (BMP-2).

Biological Activity

Cell permeable: no', 'Primary Target
HMG-CoA reductase', 'Product does not compete with ATP.', 'Reversible: no