ChemicalBook > CAS DataBase List > MLCK INHIBITOR PEPTIDE 18

MLCK INHIBITOR PEPTIDE 18

Product Name
MLCK INHIBITOR PEPTIDE 18
CAS No.
224579-74-2
Chemical Name
MLCK INHIBITOR PEPTIDE 18
Synonyms
H-RKKYKYRRK-NH2;MLCK Inhibitor Pepti;MLCK INHIBITOR PEPTIDE 18;MLCK inhibitor peptide 18,RKKYKYRRK, >98%;MYOSIN LIGHT CHAIN KINASE INHIBITOR PEPTIDE 18;L-Lysinamide, L-arginyl-L-lysyl-L-lysyl-L-tyrosyl-L-lysyl-L-tyrosyl-L-arginyl-L-arginyl-
CBNumber
CB5784116
Molecular Formula
C60H105N23O11
Formula Weight
1324.62
MOL File
224579-74-2.mol
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MLCK INHIBITOR PEPTIDE 18 Property

Density 
1.44±0.1 g/cm3(Predicted)
storage temp. 
Desiccate at -20°C
solubility 
DMF: 12 mg/mL; DMSO: 5 mg/mL; Ethanol: 12 mg/mL; PBS (pH 7.2): 5 mg/mL
form 
A crystalline solid
pka
9.82±0.15(Predicted)
color 
White to off-white
Water Solubility 
Soluble to 1 mg/ml in water
Sequence
H-Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys-NH2
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
475981
Product name
Myosin Light Chain Kinase Inhibitor Peptide 18
Purity
The Myosin Light Chain Kinase Inhibitor Peptide 18 controls the biological activity of Myosin Light Chain Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylati
Packaging
5mg
Price
$294
Updated
2025/07/31
Cayman Chemical
Product number
19181
Product name
MLCK Inhibitor Peptide 18
Purity
≥95%
Packaging
500μg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
19181
Product name
MLCK Inhibitor Peptide 18
Purity
≥95%
Packaging
1mg
Price
$61
Updated
2024/03/01
Cayman Chemical
Product number
19181
Product name
MLCK Inhibitor Peptide 18
Purity
≥95%
Packaging
5mg
Price
$214
Updated
2024/03/01
Cayman Chemical
Product number
19181
Product name
MLCK Inhibitor Peptide 18
Purity
≥95%
Packaging
10mg
Price
$396
Updated
2024/03/01
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MLCK INHIBITOR PEPTIDE 18 Chemical Properties,Usage,Production

Uses

MLCK inhibitor peptide 18 is a myosin light chain kinase (MLCK) inhibitor with an IC50 of 50 nM, and inhibits CaM kinase II only at 4000-fold higher concentrations.

Biological Activity

Cell permeable: yes', 'Primary Target
Mlck', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 50 nM against MLCK

IC 50

CaMK II

storage

Store at -20°C

References

[1] Lukas TJ, et al. Identification of novel classes of protein kinase inhibitors using combinatorial peptide chemistry based on functional genomics knowledge. J Med Chem. 1999 Mar 11;42(5):910-9.

MLCK INHIBITOR PEPTIDE 18 Preparation Products And Raw materials

Raw materials

Preparation Products

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MLCK INHIBITOR PEPTIDE 18 Suppliers

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224579-74-2, MLCK INHIBITOR PEPTIDE 18Related Search:


  • H-RKKYKYRRK-NH2
  • MYOSIN LIGHT CHAIN KINASE INHIBITOR PEPTIDE 18
  • MLCK INHIBITOR PEPTIDE 18
  • MLCK inhibitor peptide 18,RKKYKYRRK, >98%
  • L-Lysinamide, L-arginyl-L-lysyl-L-lysyl-L-tyrosyl-L-lysyl-L-tyrosyl-L-arginyl-L-arginyl-
  • MLCK Inhibitor Pepti
  • 224579-74-2
  • C60H105N23O11
  • Protein Kinase