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Boc-C1-PEG3-C4-OBn

Product Name
Boc-C1-PEG3-C4-OBn
CAS No.
2381196-81-0
Chemical Name
Boc-C1-PEG3-C4-OBn
Synonyms
Boc-C1-PEG3-C4-OBn;tert-butyl 2-[2-[2-(6-benzyloxyhexoxy)ethoxy]ethoxy]acetate;3,6,9,16-Tetraoxaheptadecanoic acid, 17-phenyl-, 1,1-dimethylethyl ester
CBNumber
CB58054684
Molecular Formula
C23H38O6
Formula Weight
410.54
MOL File
2381196-81-0.mol
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Boc-C1-PEG3-C4-OBn Property

Boiling point:
486.9±40.0 °C(Predicted)
Density 
1.029±0.06 g/cm3(Predicted)
solubility 
Soluble in DMSO
form 
Liquid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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Boc-C1-PEG3-C4-OBn Chemical Properties,Usage,Production

Biological Activity

Boc-C1-PEG3-C4-OBn (PROTAC Linker 15) is a PROTAC linker, which refers to the PEG composition. Boc-C1-PEG3-C4-OBn can be used in the synthesis of a series of PROTACs, such as PROTAC SGK3 degrader-1. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTACDegrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.

Boc-C1-PEG3-C4-OBn Preparation Products And Raw materials

Raw materials

Preparation Products

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Boc-C1-PEG3-C4-OBn Suppliers

Shanghai Kaiwei Chemical Technology Co., Ltd.
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021-58461859 15821823057
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China
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Shanghai Haohong Pharmaceutical Co., Ltd.
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Energy Chemical
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Beijing Solarbio Science & Tecnology Co., Ltd.
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010-50973130 17801761073
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Shanghai Yifei Biotechnology Co. , Ltd.
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Shandong fen Boyu Biotechnology Co.,LTD
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TargetMol Chemicals Inc.
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Shanghai Yanfen Biochemical Technology Co.,LTD
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2381196-81-0, Boc-C1-PEG3-C4-OBnRelated Search:


  • Boc-C1-PEG3-C4-OBn
  • tert-butyl 2-[2-[2-(6-benzyloxyhexoxy)ethoxy]ethoxy]acetate
  • 3,6,9,16-Tetraoxaheptadecanoic acid, 17-phenyl-, 1,1-dimethylethyl ester
  • 2381196-81-0