Rezvilutamide

Product Name: Rezvilutamide
CAS No.: 1572045-62-5
Chemical Name: Rezvilutamide
Synonyms: SHR3680;Rezvilutamide;Zavegepant Impurity 12;Benzonitrile, 4-[3-[4-[(2S)-2,3-dihydroxypropoxy]phenyl]-4,4-dimethyl-5-oxo-2-thioxo-1-imidazolidinyl]-2-(trifluoromethyl)-
CBNumber: CB58185285
Molecular Formula: C22H20F3N3O4S
Formula Weight: 479.47
MOL File: 1572045-62-5.mol

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Rezvilutamide Property

Boiling point:: 648.3±65.0 °C(Predicted)
Density: 1.50±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 100 mg/mL (208.56 mM; Need ultrasonic)
pka: 13.42±0.20(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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Rezvilutamide Chemical Properties,Usage,Production

Uses

Rezvilutamide (SHR3680) is an orally active androgen receptor antagonist. Rezvilutamide (SHR3680) is used for the study of prostate cancer[1][2].

References

[1] SangjunYoo, et al. New drugs in prostate cancer. Prostate International Volume 4, Issue 2, June 2016, Pages 37-42.
[2] Veronica Mollica, et al. Molecular Mechanisms Related to Hormone Inhibition Resistance in Prostate Cancer. Cells. 2019 Jan 11;8(1):43. DOI:10.3390/cells8010043
[3] Dai T, et al., A single-centre, open-label, single-arm, fixed-sequence pharmacokinetic study of SHR3680 on repaglinide and bupropion in prostate cancer patients. Br J Clin Pharmacol. 2023 Feb;89(2):874-886. DOI:10.1111/bcp.15528

Rezvilutamide Preparation Products And Raw materials

Raw materials

Preparation Products

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Rezvilutamide Suppliers

CHINA 13 United States 1 Global 14

TargetMol Chemicals Inc.

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Guangzhou Younan Technology Co., Ltd

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Suzhou Chenrui Biotechnology Co. LTD

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TargetMol Chemicals Inc.

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Shanghai Maclean Biochemical Technology Co., LTD

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Shanghai Yifei Biotechnology Co. , Ltd.

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Shanghai?Medlife?Pharm-Tech?Co.,?Ltd

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Sangon Biotech (Shanghai) Co.,Ltd.

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Aikon International Limited

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Hubei Rhema Reference Materials Technology Co., Ltd.

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1572045-62-5, RezvilutamideRelated Search:

Benzonitrile, 4-[3-[4-[(2S)-2,3-dihydroxypropoxy]phenyl]-4,4-dimethyl-5-oxo-2-thioxo-1-imidazolidinyl]-2-(trifluoromethyl)-

Rezvilutamide

SHR3680

Zavegepant Impurity 12

1572045-62-5