S-2238 hydrochloride

Product Name: S-2238 hydrochloride
CAS No.: 160192-34-7
Chemical Name: S-2238 hydrochloride
Synonyms: S-2238 (hydrochloride);H-D-Phe-Pip-Arg-pNA hydrochloride;(S)-1-((R)-2-amino-3-phenylpropanoyl)-N-((S)-5-guanidino-1-((4-nitrophenyl)amino)-1-oxopentan-2-yl)piperidine-2-carboxamide hydrochloride
CBNumber: CB58202971
Molecular Formula: C27H37ClN8O5
Formula Weight: 589.09
MOL File: 160192-34-7.mol

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S-2238 hydrochloride Property

solubility: DMSO: soluble
form: A solid
color: Light yellow to yellow
InChIKey: YEOVJZRYPLLHJL-IAYLHCNXNA-N
SMILES: C([C@@H]1CCCCN1C(=O)[C@H](N)CC1C=CC=CC=1)(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1C=CC(N(=O)=O)=CC=1.Cl |&1:1,9,20,r|

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Hazard and Precautionary Statements (GHS)

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S-2238 hydrochloride Chemical Properties,Usage,Production

Uses

H-D-Phe-Pip-Arg-pNA (S-2238) hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform[1][2].

References

[1] Goodnight SH Jr, et al. Measurement of antithrombin III in normal and pathologic states using chromogenic substrate S-2238. Comparison with immunoelectrophoretic and factor Xa inhibition assays. Am J Clin Pathol. 1980;73(5):639-647. DOI:10.1093/ajcp/73.5.639
[2] van Voorthuizen H, Kluft C. Improved assay conditions for automated antithrombin III determinations with the chromogenic substrate S-2238. Thromb Haemost. 1984;52(3):350-353. PMID:6531759

S-2238 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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S-2238 hydrochloride Suppliers

China 25 United States 2 Global 27

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160192-34-7, S-2238 hydrochlorideRelated Search:

H-D-Phe-Pip-Arg-pNA hydrochloride

S-2238 (hydrochloride)

(S)-1-((R)-2-amino-3-phenylpropanoyl)-N-((S)-5-guanidino-1-((4-nitrophenyl)amino)-1-oxopentan-2-yl)piperidine-2-carboxamide hydrochloride

160192-34-7