A 71623
- Product Name
- A 71623
- CAS No.
- 130408-77-4
- Chemical Name
- A 71623
- Synonyms
- A 71623;A-71623 TFA;N-Boc-L-Trp-[(2S)-2-Amino*-6-[3-(2-methylphenyl)ureido]hexanoyl]-L-Asp-N-methyl-L-Phe-NH2;N-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophyl-N6-[[(2-methylphenyl)amino]carbonyl]-L-lysyl-L-α-aspartyl-Nα-methyl-L-phenylalaninamide;L-Phenylalaninamide, N-[(1,1-dimethylethoxy)carbonyl]-L-tryptophyl-N6-[[(2-methylphenyl)amino]carbonyl]-L-lysyl-L-α-aspartyl-Nα-methyl-;N-[(1,1-DIMETHYLETHOXY)CARBONYL]-L-TRYPTOPHYL-N6-[[(2-METHYLPHENYL)AMINO]CARBONYL]-L-LYSYL-L-ALPHA-ASPARTYL-NA-METHYL-L-PHENYLALANINAMIDE
- CBNumber
- CB5829349
- Molecular Formula
- C44H56N8O9
- Formula Weight
- 840.96
- MOL File
- 130408-77-4.mol
A 71623 Property
- storage temp.
- Desiccate at -20°C
- solubility
- Soluble to 1 mg/ml in 20mM PBS buffer
- form
- solid
- color
- White
N-Bromosuccinimide Price
- Product number
- 2411
- Product name
- A-71623
- Packaging
- 1
- Price
- $306
- Updated
- 2021/12/16
- Product number
- 254494
- Product name
- A-71623
- Packaging
- 1mg
- Price
- $573
- Updated
- 2021/12/16
- Product number
- A965340
- Product name
- A-71623
- Packaging
- 1mg
- Price
- $215
- Updated
- 2021/12/16
- Product number
- BRS0000407
- Product name
- A-71623
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $782.23
- Updated
- 2021/12/16
- Product number
- B7046
- Product name
- A-71623
- Packaging
- 1mg
- Price
- $448
- Updated
- 2021/12/16
A 71623 Chemical Properties,Usage,Production
Uses
A-71623 is a potent CCK agonist with 1200-fold selectivity over the CCK2 receptor.
Biological Activity
Potent CCK 1 agonist (IC 50 = 3.7 nM) with 1200-fold selectivity over the CCK 2 receptor. Suppresses food intake following central or peripheral administration.
storage
Store at -20°C
References
[1]. gracey dj, bell r, king dj. differential effects of the ccka receptor ligands pd-140,548 and a-71623 on latent inhibition in the rat. progress in neuro-psychopharmacology and biological psychiatry, 2002, 26(3): 497-504.
[2]. lin cw, shiosaki k, miller tr, et al. characterization of two novel cholecystokinin tetrapeptide (30-33) analogues, a-71623 and a-70874, that exhibit high potency and selectivity for cholecystokinin-a receptors. molecular pharmacology, 1991, 39(3): 346-351.
[3]. kaufmann r, lindschau c, scho t, et al. type b cholecystokinin receptors on rat glioma c6 cells. binding studies and measurement of intracellular calcium mobilization. brain research, 1994, 639(1): 109-114.
A 71623 Preparation Products And Raw materials
Raw materials
Preparation Products
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