3-HYDROXYQUINOLINE-2-CARBOXYLIC ACID Property

Melting point:

187-190 °C (decomp)

Boiling point:

384.7±32.0 °C(Predicted)

Density 

1.480±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

DMSO (Slightly, Heated), Methanol (Slightly)

form 

Solid

pka

0.02±0.30(Predicted)

color 

Yellow

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

3-HYDROXYQUINOLINE-2-CARBOXYLIC ACID Chemical Properties,Usage,Production

Uses

3-Hydroxyquinoline-2-carboxylic Acid is a useful intermediate in the chromophore biosynthesis of quinomycin family antibiotics and in the total synthesis of Echinomycin and its analogs

Synthesis Reference(s)

Tetrahedron, 61, p. 1407, 2005 DOI: 10.1016/j.tet.2004.12.011