5-BROMO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE

Product Name: 5-BROMO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE
CAS No.: 858116-66-2
Chemical Name: 5-BROMO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE
Synonyms: 5-BroMo-1-triisopropylsil...;N-triisopropylsilyl-5-bromo-7-azaindole;5-Bromo-1-triisopropylsilanyl-7-azaindole;n-Triisopropylsilyl-5-bromo-7-azaindole 98%;5-Bromo-1-(triisopropylsilyl)pyrrolo[2,3-b]pyridine;5-Bromo-1-trisopropylsilanyl-1H-pyrrolo[2,3-B]pyridine;5-BROMO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE;(5-Bromopyrrolo[2,3-b]pyridin-1-yl)-triisopropyl-silane;5-broMo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine;5-BROMO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE-2
CBNumber: CB5838183
Molecular Formula: C16H25BrN2Si
Formula Weight: 353.37
MOL File: 858116-66-2.mol

More

Less

5-BROMO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE Property

Boiling point:: 333.7±35.0 °C(Predicted)
Density: 1.19±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
form: solid
pka: 2.87±0.30(Predicted)
Appearance: off-white solid

More

Less

Safety

Hazard Codes: Xi,Xn
Risk Statements: 22
HazardClass: IRRITANT
HS Code: 2933998090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: ADE000903
Product name: 5-Bromo-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine
Purity: Aldrich
Packaging: 1g
Price: $817
Updated: 2025/07/31

TRC

Product number: B699070
Product name: 5-Bromo-1-triisopropylsilanyl-1h-pyrrolo[2,3-b]pyridine
Packaging: 250mg
Price: $55
Updated: 2021/12/16

TRC

Product number: B699070
Product name: 5-Bromo-1-triisopropylsilanyl-1h-pyrrolo[2,3-b]pyridine
Packaging: 500mg
Price: $65
Updated: 2021/12/16

AK Scientific

Product number: 3356AC
Product name: 5-Bromo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine
Packaging: 25g
Price: $987
Updated: 2021/12/16

SynQuest Laboratories

Product number: 7H87-9-01
Product name: 5-Bromo-1-(triisopropylsilyl)pyrrolo[2,3-b]pyridine
Packaging: 25g
Price: $790
Updated: 2021/12/16

More

Less

5-BROMO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE Chemical Properties,Usage,Production

Synthesis

13154-24-0

858116-66-2

General procedure for the synthesis of 1-triisopropylsilyl-5-bromo-7-azaindole from triisopropylchlorosilane: Sodium hydride (0.63 g, 25.15 mmol) was added batchwise to a stirred solution of tetrahydrofuran (THF, 50 mL) of 5-bromo-7-azaindole (3.3 g, 16.75 mmol) at room temperature with continuous stirring for 15 min. Subsequently, triisopropylchlorosilane (5.3 mL, 25.15 mmol) was added and the reaction mixture was heated to 80 °C and maintained for 3 hours. After completion of the reaction, the solvent was removed by evaporation and the residue was dissolved in water (50 mL). The aqueous layer was extracted with ethyl acetate (EtOAc, 3 x 50 mL) and the organic phase was dried with anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure. The crude product was purified by Biotage HPFC system (eluent: 10% ethyl acetate/hexane) to afford the target compound 5-bromo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine as a white solid (5.2 g, 88% yield). Mass spectrometry analysis showed the molecular ion peak m/z 355 (M + 1).

References

[1] Patent: WO2005/103050, 2005, A2. Location in patent: Page/Page column 180
[2] Patent: WO2006/128692, 2006, A2. Location in patent: Page/Page column 158
[3] Patent: US2007/49615, 2007, A1. Location in patent: Page/Page column 62-63
[4] Patent: US2007/49615, 2007, A1. Location in patent: Page/Page column 68

5-BROMO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

5-BROMO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE Suppliers

China 52 India 2 United Kingdom 1 United States 9 Global 64

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 150-2103-5486 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9342
Advantage: 55

SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD.

Tel: 21-33585366 13311639313
Fax: +86-21-34979012
Email: sales@shyrchem.com
Country: China
ProdList: 806
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

Shanghai Xingui Biotechnology Co., Ltd.

Tel: 15121041756
Email: xingui2022@126.com
Country: China
ProdList: 9979
Advantage: 58

Shenzhen Gre-syn Chemical Technology Co., Ltd.

Tel: 0755-0755-89366401 18617066401
Fax: -
Email: hangbingfang@163.com
Country: China
ProdList: 951
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

More

Less

View Lastest Price from 5-BROMO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE manufacturers

Career Henan Chemical Co

Product: 5-BROMO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE 858116-66-2
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2020-02-04

858116-66-2, 5-BROMO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINERelated Search:

5-bromo-1,2-dihydro-3H-Pyrazolo[3,4-b]pyridin-3-one Tiotropium bromide 5-BROMO-3-IODO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE 5-Bromo-7-azaindole 5-BROMO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE 1-(TRIISOPROPYLSILYL)PYRROLE

5-BROMO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE

5-Bromo-1-triisopropylsilanyl-7-azaindole

N-triisopropylsilyl-5-bromo-7-azaindole

5-Bromo-1-(triisopropylsilyl)pyrrolo[2,3-b]pyridine

n-Triisopropylsilyl-5-bromo-7-azaindole 98%

(5-bromo-1-pyrrolo[2,3-b]pyridinyl)-tri(propan-2-yl)silane

5-broMo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine

5-BroMo-1-triisopropylsil...

5-BROMO-1-TRIISOPROPYLSILANYL-1H-PYRROLO[2,3-B]PYRIDINE-2

5-bromo-1-[tris(propan-2-yl)silyl]-1H-pyrrolo[2,3-b]pyridine

(5-Bromopyrrolo[2,3-b]pyridin-1-yl)-triisopropyl-silane

1H-Pyrrolo[2,3-b]pyridine, 5-bromo-1-[tris(1-methylethyl)silyl]-

5-Bromo-1-trisopropylsilanyl-1H-pyrrolo[2,3-B]pyridine

5-Bromo-1-[tris(1-methylethyl)silyl]-1H-pyrrolo[2,3-b]pyridine

858116-66-2

C16H25BrN2Si