ChemicalBook > CAS DataBase List > 4-MORPHOLIN-4-YL-BUTAN-1-OL

4-MORPHOLIN-4-YL-BUTAN-1-OL

Product Name
4-MORPHOLIN-4-YL-BUTAN-1-OL
CAS No.
5835-79-0
Chemical Name
4-MORPHOLIN-4-YL-BUTAN-1-OL
Synonyms
AKOS BB/0085;AKOS BBB/436;CHEMBRDG-BB 4001148;4-Morpholinebutanol;4-Morpholino-1-butanol;4-Morpholinobutan-1-ol;4-MORPHOLIN-4-YL-BUTAN-1-OL;4-morpholin-4-ylbutan-1-ol(SALTDATA: FREE)
CBNumber
CB5838471
Molecular Formula
C8H17NO2
Formula Weight
159.23
MOL File
5835-79-0.mol
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4-MORPHOLIN-4-YL-BUTAN-1-OL Property

storage temp. 
2-8°C
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Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC
Product number
M732733
Product name
4-(4-Morpholinyl)-1-butanol
Packaging
100mg
Price
$65
Updated
2021/12/16
TRC
Product number
M732733
Product name
4-(4-Morpholinyl)-1-butanol
Packaging
1g
Price
$330
Updated
2021/12/16
Apolloscientific
Product number
OR963360
Product name
4-(4-Morpholinyl)-1-butanol
Purity
95%
Packaging
1g
Price
$345
Updated
2021/12/16
Matrix Scientific
Product number
024209
Product name
4-(4-Morpholinyl)-1-butanol
Packaging
1g
Price
$154
Updated
2021/12/16
Matrix Scientific
Product number
024209
Product name
4-(4-Morpholinyl)-1-butanol
Packaging
500mg
Price
$101
Updated
2021/12/16
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4-MORPHOLIN-4-YL-BUTAN-1-OL Chemical Properties,Usage,Production

Synthesis

110-91-8

928-51-8

5835-79-0

Example 3; 1-(4-Hydroxybutyl)morpholine was synthesized as follows: to a 250 mL three-necked flask were sequentially added morpholine (65.5 g, 750 mmol), 4-chloro-1-butanol (27.2 g, 250 mmol), sodium iodide (3.8 g, 25 mmol) and 75 mL of dioxane. The reaction mixture was heated to reflux for 48 hours. After completion of the reaction, the mixture was cooled to room temperature. The solvent was removed by rotary evaporator to give a brown oily crude product. The crude product was dissolved in 100 mL of 2N sodium hydroxide solution, extracted with ethyl acetate (EtOAc), the organic phases were combined and dried over anhydrous sodium sulfate (Na2SO4). After removal of the desiccant by filtration, the solvent was removed by distillation under reduced pressure to give an orange colored oil. Finally, the oily substance was subjected to reduced pressure distillation (90 °C, 1 mmHg) to collect the target product 1-(4-hydroxybutyl)morpholine (13.9 g, 87 mmol, 35% yield) as a colorless oil.

References

[1] Patent: WO2008/66874, 2008, A1. Location in patent: Page/Page column 74-75
[2] Journal of the American Chemical Society, 1939, vol. 61, p. 3439
[3] Journal of the American Chemical Society, 1942, vol. 64, p. 970,972

4-MORPHOLIN-4-YL-BUTAN-1-OL Preparation Products And Raw materials

Raw materials

Preparation Products

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4-MORPHOLIN-4-YL-BUTAN-1-OL Suppliers

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