ChemicalBook > CAS DataBase List > 1-[2-(4-HYDROXYPHENOXY)ETHYL]-4-[(4-METHYLPHENYL)METHYL]-4-PIPERIDINOL MONOHYDROCHLORIDE

1-[2-(4-HYDROXYPHENOXY)ETHYL]-4-[(4-METHYLPHENYL)METHYL]-4-PIPERIDINOL MONOHYDROCHLORIDE

Product Name
1-[2-(4-HYDROXYPHENOXY)ETHYL]-4-[(4-METHYLPHENYL)METHYL]-4-PIPERIDINOL MONOHYDROCHLORIDE
CAS No.
193359-26-1
Chemical Name
1-[2-(4-HYDROXYPHENOXY)ETHYL]-4-[(4-METHYLPHENYL)METHYL]-4-PIPERIDINOL MONOHYDROCHLORIDE
Synonyms
184832;Co 101244;CO-101244 Free Base;CO 101244 HYDROCHLORIDE;1-(2-(4-hydroxyphenoxy)ethyl)-4-(4-methylbenzyl)piperidin-4-ol;4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-;1-[2-(4-Hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]-4-piperidinolhydrochloride;1-[2-(4-HYDROXYPHENOXY)ETHYL]-4-[(4-METHYLPHENYL)METHYL]-4-PIPERIDINOL MONOHYDROCHLORIDE
CBNumber
CB5849466
Molecular Formula
C21H27NO3
Formula Weight
341.44
MOL File
193359-26-1.mol
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1-[2-(4-HYDROXYPHENOXY)ETHYL]-4-[(4-METHYLPHENYL)METHYL]-4-PIPERIDINOL MONOHYDROCHLORIDE Property

Boiling point:
527.9±45.0 °C(Predicted)
Density 
1.169±0.06 g/cm3(Predicted)
storage temp. 
Store at +4°C
pka
10.31±0.15(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
2456
Product name
Co101244hydrochloride
Purity
≥99%(HPLC)
Packaging
10
Price
$195
Updated
2021/12/16
Tocris
Product number
2456
Product name
Co101244hydrochloride
Purity
≥99%(HPLC)
Packaging
50
Price
$818
Updated
2021/12/16
Usbiological
Product number
255018
Product name
Co 101244 hydrochloride
Packaging
10mg
Price
$438
Updated
2021/12/16
TRC
Product number
C781008
Product name
Co101244
Packaging
50mg
Price
$660
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0009710
Product name
RO-631908
Purity
95.00%
Packaging
10MG
Price
$709.46
Updated
2021/12/16
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1-[2-(4-HYDROXYPHENOXY)ETHYL]-4-[(4-METHYLPHENYL)METHYL]-4-PIPERIDINOL MONOHYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Co 101244 is a highly selective N-methyl-D-aspartate NR2B subtype antagonist.

Biological Activity

Novel, potent and selective antagonist of NR2B-containing NMDA receptors (IC 50 values are 0.043, > 100 and > 100 μ M for NR1A/2B, NR1A/2A and NR1A/2C subunit combinations respectively). Displays neuroprotective effects in vivo and in vitro .

1-[2-(4-HYDROXYPHENOXY)ETHYL]-4-[(4-METHYLPHENYL)METHYL]-4-PIPERIDINOL MONOHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-[2-(4-HYDROXYPHENOXY)ETHYL]-4-[(4-METHYLPHENYL)METHYL]-4-PIPERIDINOL MONOHYDROCHLORIDE Suppliers

Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77

193359-26-1, 1-[2-(4-HYDROXYPHENOXY)ETHYL]-4-[(4-METHYLPHENYL)METHYL]-4-PIPERIDINOL MONOHYDROCHLORIDERelated Search:


  • 184832
  • Co 101244
  • 1-[2-(4-HYDROXYPHENOXY)ETHYL]-4-[(4-METHYLPHENYL)METHYL]-4-PIPERIDINOL MONOHYDROCHLORIDE
  • CO 101244 HYDROCHLORIDE
  • 1-[2-(4-Hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]-4-piperidinolhydrochloride
  • 4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-
  • 1-(2-(4-hydroxyphenoxy)ethyl)-4-(4-methylbenzyl)piperidin-4-ol
  • CO-101244 Free Base
  • 193359-26-1