Desthiobiotin-PEG3-Amine

Product Name: Desthiobiotin-PEG3-Amine
CAS No.: 2237234-71-6
Chemical Name: Desthiobiotin-PEG3-Amine
Synonyms: Desthiobiotin-PEG3-Amine;4-Imidazolidinehexanamide, N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-5-methyl-2-oxo-, (4R,5S)-
CBNumber: CB58512784
Molecular Formula: C18H36N4O5
Formula Weight: 388.5
MOL File: 2237234-71-6.mol

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Desthiobiotin-PEG3-Amine Property

Boiling point:: 642.6±45.0 °C(Predicted)
Density: 1.074±0.06 g/cm3(Predicted)
pka: 14.93±0.60(Predicted)
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Desthiobiotin-PEG3-Amine Chemical Properties,Usage,Production

Uses

Amine-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Biological Activity

Amine-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Desthiobiotin-PEG3-Amine Preparation Products And Raw materials

Raw materials

Preparation Products

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Desthiobiotin-PEG3-Amine Suppliers

China 8 United States 1 Global 9

Xi'an Confluore Biological Technology Co., Ltd.

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BOC Sciences

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Xian confluore Biological Technology Co., Ltd.

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View Lastest Price from Desthiobiotin-PEG3-Amine manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Desthiobiotin-PEG3-Amine 2237234-71-6
Price: US $0.00/mg
Min. Order: 100mg
Purity: >98.00%
Supply Ability: 100mg
Release date: 2024-03-30

2237234-71-6, Desthiobiotin-PEG3-AmineRelated Search:

Desthiobiotin-PEG3-DBCO Desthiobiotin-PEG3-NHS ester Azide-PEG3-Desthiobiotin Desthiobiotin-PEG3-Alkyne

Desthiobiotin-PEG3-Amine

4-Imidazolidinehexanamide, N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-5-methyl-2-oxo-, (4R,5S)-

2237234-71-6