MAF
- Product Name
- MAF
- CAS No.
- 101365-54-2
- Chemical Name
- MAF
- Synonyms
- MAF;C-Maf;4hopcp;4-ho-pcp;MAF power;IFN-γ human;T cell interferon;Immune Interferon;type II interferon;Proto-oncogene c-maf
- CBNumber
- CB5852420
- Molecular Formula
- C22H29ClN2O2
- Formula Weight
- 388.94
- MOL File
- Mol file
MAF Property
- storage temp.
- -20°C
- solubility
- DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 20 mg/ml; Methanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
- form
- A neat solid
- Stability:
- Hygroscopic
Safety
- RIDADR
- UN1230 - class 3 - PG 2 - Methanol, solution
N-Bromosuccinimide Price
- Product number
- M-200
- Product name
- Methoxyacetyl fentanyl hydrochloride solution
- Purity
- 100?μg/mL in methanol (as free base), certified reference material, ampule of 0.5?mL, Cerilliant?
- Packaging
- 0.5ml
- Price
- $115
- Updated
- 2024/03/01
- Product number
- SRP3058
- Product name
- IFN-γ human
- Purity
- Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
- Packaging
- 100μG
- Price
- $366
- Updated
- 2022/05/15
- Product number
- 20782
- Product name
- Methoxyacetyl fentanyl (hydrochloride)
- Packaging
- 1mg
- Price
- $79
- Updated
- 2023/06/20
- Product number
- 23540
- Product name
- Methoxyacetyl fentanyl (hydrochloride) (CRM)
- Packaging
- 1mg
- Price
- $116
- Updated
- 2023/06/20
- Product number
- 20782
- Product name
- Methoxyacetyl fentanyl (hydrochloride)
- Packaging
- 5mg
- Price
- $348
- Updated
- 2023/06/20
MAF Chemical Properties,Usage,Production
Uses
IFN-γ (interferon γ)-human has been used for the generation of inflammatory M1 cells from human monocytic cell line, THP1.
General Description
IFN-γ (interferon γ) is an acid-labile glycosylated interferon produced by CD4 and CD8 T lymphocytes as well as activated NK (natural killer) cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC (major histocompatibility complex) proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. The gene is mapped to human chromosome 12q15. Human IFN-γ is species-specific and is biologically active only in human and primate cells. Recombinant human IFN-γ is a 16.7kDa protein containing 143 amino acid residues.
Biochem/physiol Actions
IFN-γ (interferon γ) signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. It can suppress the generation of anti-inflammatory cytokines and enhance the secretion of proinflammatory cytokines. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK (natural killer) cells and neutrophils. It is responsible for tumor rejection and is capable of killing tumor cells by autophagy or apoptosis. IFN-γ is also involved in Hepatitis E virus disease pathogenesis.