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MAF

Product Name
MAF
CAS No.
101365-54-2
Chemical Name
MAF
Synonyms
MAF;C-Maf;4hopcp;4-ho-pcp;MAF power;IFN-γ human;T cell interferon;Immune Interferon;type II interferon;Proto-oncogene c-maf
CBNumber
CB5852420
Molecular Formula
C22H29ClN2O2
Formula Weight
388.94
MOL File
Mol file
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MAF Property

storage temp. 
-20°C
solubility 
DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 20 mg/ml; Methanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form 
A neat solid
Stability:
Hygroscopic
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Safety

RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M-200
Product name
Methoxyacetyl fentanyl hydrochloride solution
Purity
100?μg/mL in methanol (as free base), certified reference material, ampule of 0.5?mL, Cerilliant?
Packaging
0.5ml
Price
$115
Updated
2024/03/01
Sigma-Aldrich
Product number
SRP3058
Product name
IFN-γ human
Purity
Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
Packaging
100μG
Price
$366
Updated
2022/05/15
Cayman Chemical
Product number
20782
Product name
Methoxyacetyl fentanyl (hydrochloride)
Packaging
1mg
Price
$79
Updated
2023/06/20
Cayman Chemical
Product number
23540
Product name
Methoxyacetyl fentanyl (hydrochloride) (CRM)
Packaging
1mg
Price
$116
Updated
2023/06/20
Cayman Chemical
Product number
20782
Product name
Methoxyacetyl fentanyl (hydrochloride)
Packaging
5mg
Price
$348
Updated
2023/06/20
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MAF Chemical Properties,Usage,Production

Uses

IFN-γ (interferon γ)-human has been used for the generation of inflammatory M1 cells from human monocytic cell line, THP1.

General Description

IFN-γ (interferon γ) is an acid-labile glycosylated interferon produced by CD4 and CD8 T lymphocytes as well as activated NK (natural killer) cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC (major histocompatibility complex) proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. The gene is mapped to human chromosome 12q15. Human IFN-γ is species-specific and is biologically active only in human and primate cells. Recombinant human IFN-γ is a 16.7kDa protein containing 143 amino acid residues.

Biochem/physiol Actions

IFN-γ (interferon γ) signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. It can suppress the generation of anti-inflammatory cytokines and enhance the secretion of proinflammatory cytokines. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK (natural killer) cells and neutrophils. It is responsible for tumor rejection and is capable of killing tumor cells by autophagy or apoptosis. IFN-γ is also involved in Hepatitis E virus disease pathogenesis.

MAF Preparation Products And Raw materials

Raw materials

Preparation Products

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MAF Suppliers

101365-54-2, MAFRelated Search:


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