ChemicalBook > CAS DataBase List > nitrofurantoin sodium

nitrofurantoin sodium

Product Name
nitrofurantoin sodium
CAS No.
54-87-5
Chemical Name
nitrofurantoin sodium
Synonyms
Ivadantin;Einecs 200-216-7;Sodium furadantin;nitrofurantoin sodium;Nitrofurandantoin sodium;NITROFURANTOIN, SODIUM SALT;Hydantoin, 1-((5-nitrofurfurylidene)amino)-, sodium salt;1-[(5-nitrofurfurylidene)amino]imidazolidine-2,4-dione, sodium salt;1-[[(5-Nitro-2-furanyl)methylene]amino]-2-sodiooxyimidazolidin-4-one;1-[[(5-Nitro-2-furanyl)methylene]amino]-2-sodiooxyimidazolidine-4-one
CBNumber
CB5875407
Molecular Formula
C8H7N4NaO5
Formula Weight
262.16
MOL File
54-87-5.mol
More
Less

Safety

RIDADR 
3249
HazardClass 
6.1(b)
PackingGroup 
III
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0008933
Product name
NITROFURANTOIN SODIUM
Purity
95.00%
Packaging
5MG
Price
$499.36
Updated
2021/12/16
AvaChem
Product number
3803
Product name
Nitrofurantoin Sodium
Packaging
25mg
Price
$69
Updated
2021/12/16
AvaChem
Product number
3803
Product name
Nitrofurantoin Sodium
Packaging
100mg
Price
$189
Updated
2021/12/16
More
Less

nitrofurantoin sodium Chemical Properties,Usage,Production

Uses

Nitrofurantoin sodium is a potent and orally active antibacterial agent. Nitrofurantoin sodium acts as an antibiotic. Nitrofurantoin sodium can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections[1][2].

brand name

Ivadantin (Procter & Gamble).

in vivo

1.19Nitrofurantoin pharmacokinetic effects in SD Rats[4].
Parameters10 mg/kg p.o.2 mg/kg i.v.
AUC0-720 (μg/mL?min)306
AUC0-120 (μg/mL?min)90.3
AUC0-∞ (μg/mL?min)34491.5
Cmax (μg/mL)1.01
CL/F or CL (ml/min/kg)31.022.7
t1/2 (min)16623.6
Bioavailability (%)60.1

References

[1] Huttner A, et al. Nitrofurantoin revisited: a systematic review and meta-analysis of controlled trials. J Antimicrob Chemother. 2015 Sep;70(9):2456-64. DOI:10.1093/jac/dkv147
[2] Garau J. Other antimicrobials of interest in the era of extended-spectrum beta-lactamases: fosfomycin, nitrofurantoin and tigecycline. Clin Microbiol Infect. 2008 Jan;14 Suppl 1:198-202. DOI:10.1111/j.1469-0691.2007.01852.x
[3] Linus Sandegren, et al. Nitrofurantoin resistance mechanism and fitness cost in Escherichia coli. J Antimicrob Chemother. 2008 Sep;62(3):495-503. DOI:10.1093/jac/dkn222
[4] Xiaodong Wang, et al. Effects of the flavonoid chrysin on nitrofurantoin pharmacokinetics in rats: potential involvement of ABCG2. Drug Metab Dispos. 2007 Feb;35(2):268-74. DOI:10.1124/dmd.106.011684

nitrofurantoin sodium Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

nitrofurantoin sodium Suppliers

China 6 United States 2 Global 8
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
14912
Advantage
59
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
029-029-029-81148696 18161915376
Email
1040@dideu.com
Country
China
ProdList
10001
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Naturewill Biotechnology Co., Ltd.
Tel
028-82632533 18113192475
Email
3157321941@qq.com
Country
China
ProdList
4993
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
Country
China
ProdList
12000
Advantage
58
Chongqing jooe co., ltd
Tel
+undefined86-15223382610
Email
info@jooe.com
Country
China
ProdList
6208
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58

54-87-5, nitrofurantoin sodiumRelated Search:

Nitrofurantoin nitrofurantoin sodium

  • nitrofurantoin sodium
  • 1-[(5-nitrofurfurylidene)amino]imidazolidine-2,4-dione, sodium salt
  • NITROFURANTOIN, SODIUM SALT
  • 1-[[(5-Nitro-2-furanyl)methylene]amino]-2-sodiooxyimidazolidin-4-one
  • 1-[[(5-Nitro-2-furanyl)methylene]amino]-2-sodiooxyimidazolidine-4-one
  • Ivadantin
  • 2,4-Imidazolidinedione, 1-(((5-nitro-2-furanyl)methylene)amino)-, sodium salt (9ci)
  • Einecs 200-216-7
  • Hydantoin, 1-((5-nitrofurfurylidene)amino)-, sodium salt
  • Nitrofurandantoin sodium
  • Sodium furadantin
  • sodium,3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-5-oxo-4H-imidazol-2-olate
  • 54-87-5