mefruside

Product Name: mefruside
CAS No.: 7195-27-9
Chemical Name: mefruside
Synonyms: B 1500;FDA 1902;FBA 1500;Baycaron;BAY 1500;Mefrusid;mefruside;Valine Impurity 35;mefruside USP/EP/BP;N-(4-Chloro-3-sulfamoylbenzenesulfonyl)-N-methyl-2-furfurylamine
CBNumber: CB5875654
Molecular Formula: C13H19ClN2O5S2
Formula Weight: 382.88
MOL File: 7195-27-9.mol

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mefruside Property

Melting point:: 149.5°C
Boiling point:: 565.2±60.0 °C(Predicted)
Density: 1.3150 (rough estimate)
refractive index: 1.6100 (estimate)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 9.26±0.60(Predicted)
color: White to Pale Beige
Stability:: Hygroscopic

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Safety

Toxicity: LD50 oral in rabbit: > 3gm/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: M205150
Product name: Mefruside
Packaging: 5mg
Price: $260
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0011858
Product name: MEFRUSIDE
Purity: 95.00%
Packaging: 1MG
Price: $329.7
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0011858
Product name: MEFRUSIDE
Purity: 95.00%
Packaging: 5MG
Price: $502.29
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 59614
Product name: Mefruside
Packaging: 1mg
Price: $650
Updated: 2021/12/16

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mefruside Chemical Properties,Usage,Production

Originator

Baycaron,Bayer,W. Germany,1967

Uses

Mefruside is a diuretic used for the treatment of edema and hypertension.

Definition

ChEBI: Mefruside is an organic molecular entity.

Manufacturing Process

By hydrogenation of α-methyl-α-cyanotetrahydrofuran with Raney nickel as catalyst, α-methyl-α-tetrahydrofurfuryl amine is obtained (BP 48°C/12 mm Hg) which is alkylated by dimethyl sulfate to give α-methyl-αtetrahydrofurfurylmethylamine (BP 70°C/40 mm Hg). The amine is then reacted with 4-chloro-3-sulfamyl benzene sulfochloride in the presence of an acid acceptor. The mixture is stirred overnight, the solvent (acetone or pyridine) is driven off under vacuum and the residue is recrystallized from alcohol.

Therapeutic Function

Diuretic

mefruside Preparation Products And Raw materials

Raw materials

Preparation Products

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mefruside Suppliers

Canada 1 China 20 India 2 United States 6 Global 29

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14055
Advantage: 65

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57423
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 22787
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24644
Advantage: 58

Shaanxi Dideu Newmaterial Co., Ltd.

Tel: 029-87576359 15353716720
Email: 1039@dideu.com
Country: China
ProdList: 10009
Advantage: 58

LGC Science (Shanghai) Ltd.

Tel: 17717235263
Email: cindy.yang@lgcgroup.com
Country: China
ProdList: 17730
Advantage: 58

guoyungurui

Tel: 18162595016; 18162595016
Email: 3287908757@qq.com
Country: China
ProdList: 10335
Advantage: 58

TargetMol Chemicals Inc.

Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Country: United States
ProdList: 19881
Advantage: 58

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View Lastest Price from mefruside manufacturers

Dideu Industries Group Limited

Product: mefruside 7195-27-9
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-08

7195-27-9, mefrusideRelated Search:

2-Methyltetrahydrofuran Furfurylamine mefruside CLOFENAMIDE tetrahydrofurfuryl-2-methylamine

1,3-Benzenedisulfonamide, 4-chloro-N1-methyl-N1-[(tetrahydro-2-methyl-2-furanyl)methyl]- (9CI)

4-Chloro-N1-methyl-N1-(tetrahydro-2-methylfurfuryl)-m-benzenedisulfonamide

B 1500

BAY 1500

Baycaron

FBA 1500

FDA 1902

m-Benzenedisulfonamide, 4-chloro-N1-methyl-N1-(tetrahydro-2-methylfurfuryl)- (7CI, 8CI)

N-(4'-Chloro-3'-sulfamoylbenzenesulfonyl)-N-methyl-2-aminomethyl-2-methyltetrahydrofuran

N-(4-Chloro-3-sulfamoylbenzenesulfonyl)-N-methyl-2-furfurylamine

mefruside

4-Chloro-N-methyl-N-(tetrahydro-2-methylfuran-2-yl)-1,3-benzenedisulfonamide

Mefrusid

4-chloro-1-N-methyl-1-N-[(2-methyloxolan-2-yl)methyl]benzene-1,3-disulfonamide

4-chloro-N1-methyl-N1-[(2-methyloxolan-2-yl)methyl]benzene-1,3-disulfonamide

4-chloro-N-methyl-N-[(2-methyltetrahydrofuran-2-yl)methyl]benzene-1,3-disulfonamide

mefruside USP/EP/BP

1,3-Benzenedisulfonamide, 4-chloro-N1-methyl-N1-[(tetrahydro-2-methyl-2-furanyl)methyl]-

Valine Impurity 35

7195-27-9

C13H19ClN2O5S2