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oxophenarsine hydrochloride

Product Name
oxophenarsine hydrochloride
CAS No.
538-03-4
Chemical Name
oxophenarsine hydrochloride
Synonyms
MAPHARSEN;ARSENOXIDE;MAPHARSIDE;oxophenarsine hydrochloride
CBNumber
CB5912407
Molecular Formula
C6H6AsNO2.ClH
Formula Weight
235.501
MOL File
538-03-4.mol
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Safety

Toxicity
LD50 oral in mouse: 110ug/kg
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
OGM0002393
Product name
OXOPHENARSINE HYDROCHLORIDE
Purity
95.00%
Packaging
5MG
Price
$496.29
Updated
2021/12/16
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oxophenarsine hydrochloride Chemical Properties,Usage,Production

brand name

Mapharsen (Parke-Davis).

Pharmaceutical Applications

In 1930, the oxidised compound Oxophenarsine, containing an As=O unit, was identified as the active ingredient and was later marketed under the trade name Mapharsen. Mapharsen was used until the 1940s when it was replaced by Penicillin. Mapharsen was actually synthesised in Ehrlich’s laboratory as compound number 5, but it was believed to be too toxic for any clinical application .
Generally, the use of arsenic-based drugs has ceased, especially as a result of the development of Penicillin. Nevertheless, Melarsoprol and an arsenic-based drug closely related to Atoxyl are licensed to treat sleeping sickness.

Safety Profile

Poison by ingestion, intravenous,and intraperitoneal routes. Human systemic effects byingestion: stroke, convulsions, and coma. When heated todecomposition it emits very toxic fumes of As, NOx, andHCl. An antirickettsial and antitrypanosomal agent.

oxophenarsine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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oxophenarsine hydrochloride Suppliers

Shaanxi Dideu Medichem Co. Ltd
Tel
+86-29-87569266 15319487004
Fax
029-88380327
Email
1015@dideu.com
Country
China
ProdList
4087
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
029-61856358 15229202216
Fax
029-88380327
Email
1020@dideu.com
Country
China
ProdList
10009
Advantage
58

538-03-4, oxophenarsine hydrochlorideRelated Search:


  • oxophenarsine hydrochloride
  • MAPHARSIDE
  • ARSENOXIDE
  • MAPHARSEN
  • 538-03-4
  • C6H7AsClNO2