morinamide
- Product Name
- morinamide
- CAS No.
- 952-54-5
- Chemical Name
- morinamide
- Synonyms
- B 2310;morinamide;Morfazinamide;morphazinamide;N-(Morpholinomethyl)-2-pyrazinecarboxamide;2-Pyrazinecarboxamide, N-(4-morpholinylmethyl)-;pyrazine-2-carboxylic acid morpholin-4-ylmethyl-amide
- CBNumber
- CB5936067
- Molecular Formula
- C10H14N4O2
- Formula Weight
- 222.24
- MOL File
- 952-54-5.mol
morinamide Property
- Melting point:
- 118.5-119.5°
N-Bromosuccinimide Price
- Product number
- M651765
- Product name
- Morphazinamide
- Packaging
- 500mg
- Price
- $880
- Updated
- 2021/12/16
- Product number
- API0011982
- Product name
- MORINAMIDE
- Purity
- 95.00%
- Packaging
- 50MG
- Price
- $2194.5
- Updated
- 2021/12/16
- Product number
- API0011982
- Product name
- MORINAMIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $816.75
- Updated
- 2021/12/16
morinamide Chemical Properties,Usage,Production
Originator
Morinamide,Bracco Industria Chimica S.p.A.
Uses
Morphazinamide is an anti-tuberculosis agent. Also, it is derived from Pyrazinamide (P840600), which is an anti-bacterial (tuberculostatic).
Definition
ChEBI: Morinamide is a member of pyrazines, a secondary carboxamide and a member of morpholines.
Manufacturing Process
98.5 parts by weight 2-pyrazinecarboxamide was mixed with 260 parts by
volume of diethylamine. 91 parts by weight of 37% formaldehyde was added
to above mixture by stirring for 30 minutes. The reaction mixture was
spontaneously heated to 50°C. Then it heated to reflux for 5 hours on water
bath. After that it was distilled to dryness at temperature between 40°-50°C.
The residue was dissolved with about 200 parts by volume of ligroin (B.P.
60°C) by heating. The solution was filtered hot for removing the not reacted
2-pyrazinecarboxamide. Then it was cooled to -10°C and desired N-
(diethylaminomethyl)-pyrazinecarboxylic acid amide discharged. It was filtered
off and recrystallized from light petrol ester. Yield about 90%, MP: 47°-50°C.
500 parts by weight of N-(diethylaminomethyl)pyrazinecarboxylic acid amide
and 2500 parts by volume of was mixed and heated by stirring to temperature
140°-150°C. At 60°-100°C a distillation begun and ended at 127°C (a boiling
point of morpholine). The distillate consisted from diethylamine and
morpholine. After 30-60 minutes the mixture was cooled to 50°C and distilled
in vacuum to dryness. The residue was recrystallized from 400 parts by
volume of benzene to give N-(morpholinomethyl)pyrazinecarboxamide, yield
92%, MP: 114°-117°C.
Therapeutic Function
Antitubercular
morinamide Preparation Products And Raw materials
Raw materials
Preparation Products
morinamide Suppliers
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- 15229059051
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- Country
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