iopydol
- Product Name
- iopydol
- CAS No.
- 5579-92-0
- Chemical Name
- iopydol
- Synonyms
- iopydol;Iopidol;Iopidolo;Iopydolum;Jopydolum;EINECS 226-968-6;1-glyceryl-3,5-diiodo-4-pyridone;1-(2,3-dihydroxypropyl)-3,5-diiodopyridin-4-one;1-(2,3-dihydroxypropyl)-3,5-diiodo-pyridin-4-one;1-(2,3-Dihydroxypropyl)-3,5-diiodo-4(1H)-pyridone
- CBNumber
- CB5941333
- Molecular Formula
- C8H9I2NO3
- Formula Weight
- 420.97
- MOL File
- 5579-92-0.mol
iopydol Property
- Melting point:
- 161°
N-Bromosuccinimide Price
- Product number
- 452427
- Product name
- Iopydol
- Packaging
- 5mg
- Price
- $382
- Updated
- 2021/12/16
- Product number
- I821873
- Product name
- Iopydol
- Packaging
- 50mg
- Price
- $715
- Updated
- 2021/12/16
- Product number
- API0011686
- Product name
- IOPYDOL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.83
- Updated
- 2021/12/16
iopydol Chemical Properties,Usage,Production
Originator
Hytrast Vial,Guerbet
Uses
Diagnostic aid (radiopaque medium, bronchographic) .
Uses
Iopydol is the X-ray contrast reagent.
Definition
ChEBI: Iopydol is a chloropyridine.
Manufacturing Process
50 g 4-pyridone was dissolved in 300 ml 20% hydrochloric acid and slowly
mixed with 180 g of chloroiodide in 200 ml 20% hydrochloric acid. Then the
obtained dark solution was strong alkalized with sodium hydroxide. The
solvent was removed to dryness and sodium salt diiod-4-pyridone was
obtained. It was dissolved in water, filtered and equivalent quantity of glacial
acetic acid or hydrochloric acid was added to give 3,5-diiod-4-pyridone as a
powder. 34.5 g 3,5-diiod-pyridone was dissolved in 100 ml 1 N NaOH by
heating on a water bath and added to a 15 g of monochlorohydrine added.
The mixture was heated on water bath before a dense pasty mass obtained. It
was filtered off and treated with 1 N NaOH. The obtained 1-(2,3-
dihydroxypropyl)-3,5-diiodo-4(1H)-pyridinone was recrystallized from diluted
hydrochloric acid. MP: 161°C.
Therapeutic Function
Diagnostic aid
iopydol Preparation Products And Raw materials
Raw materials
Preparation Products
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