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2,4-DIMETHYL-3-PYRROLEPROPIONIC ACID

Product Name
2,4-DIMETHYL-3-PYRROLEPROPIONIC ACID
CAS No.
54474-50-9
Chemical Name
2,4-DIMETHYL-3-PYRROLEPROPIONIC ACID
Synonyms
2,4-DIMETHYL-3-PYRROLEPROPIONIC ACID;1H-Pyrrole-3-propanoic acid, 2,4-dimethyl-;3-(2,4-DIMETHYL-1H-PYRROL-3-YL)PROPANOIC ACID;tert-Butyl (4-aminobut-2-en-1-yl)carbamate hydrochloride
CBNumber
CB6103143
Molecular Formula
C9H13NO2
Formula Weight
167.21
MOL File
54474-50-9.mol
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2,4-DIMETHYL-3-PYRROLEPROPIONIC ACID Property

Melting point:
140-141 °C
Boiling point:
332.8±37.0 °C(Predicted)
Density 
1.159±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
4.68±0.10(Predicted)
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

AK Scientific
Product number
5736AQ
Product name
3-(2,4-Dimethyl-1H-pyrrol-3-yl)propanoicacid
Packaging
1g
Price
$512
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0019580
Product name
2,4-DIMETHYL-3-PYRROLEPROPIONIC ACID
Purity
95.00%
Packaging
1G
Price
$1095.12
Updated
2021/12/16
Crysdot
Product number
CD11107045
Product name
3-(2,4-Dimethyl-1H-pyrrol-3-yl)propanoicacid
Purity
97%
Packaging
10g
Price
$1386
Updated
2021/12/16
Chemenu
Product number
CM125785
Product name
3-(2,4-dimethyl-1H-pyrrol-3-yl)propanoicacid
Purity
95%+
Packaging
5g
Price
$1846
Updated
2021/12/16
Crysdot
Product number
CD11107045
Product name
3-(2,4-Dimethyl-1H-pyrrol-3-yl)propanoicacid
Purity
97%
Packaging
5g
Price
$891
Updated
2021/12/16
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2,4-DIMETHYL-3-PYRROLEPROPIONIC ACID Chemical Properties,Usage,Production

Synthesis

2386-37-0

54474-50-9

General procedure for the synthesis of 2,4-dimethyl-3-pyrrolepropionic acid from ethyl 4-(3-methoxy-3-oxopropyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate: ethyl 4-(2-methoxycarbonylethyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate (Aldrich, 228 g, 0.9 mol) was reacted with 720 mL of 5 N sodium hydroxide solution were mixed and reacted at reflux for 1 hour. The progress of the reaction was monitored by thin layer chromatography (TLC) to confirm the completion of the hydrolysis reaction. The reaction mixture was cooled to 50 °C with stirring, and the pH was adjusted to 2-3 by slowly adding 10 N hydrochloric acid (390 mL). after solidification of the oil was observed, stirring was continued and the mixture was cooled to 4 °C. The reaction was then purified by vacuum filtration. The solid product was collected by vacuum filtration, washed well with water and subsequently dried under vacuum at 40 °C to afford 65.7 g (49% yield) of 3-(2,4-dimethyl-1H-pyrrol-3-yl)propionic acid as a slightly red solid.

References

[1] Journal of Organic Chemistry, 1988, vol. 53, # 12, p. 2796 - 2802
[2] Patent: US2004/204407, 2004, A1. Location in patent: Page/Page column 16-17
[3] Patent: US2004/266843, 2004, A1. Location in patent: Page 12

2,4-DIMETHYL-3-PYRROLEPROPIONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4-DIMETHYL-3-PYRROLEPROPIONIC ACID Suppliers

China 35 France 1 Germany 1 India 1 United Kingdom 1 United States 7 Global 46
Fulcrum Scientific Ltd.
Tel
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Fax
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Country
United Kingdom
ProdList
6565
Advantage
38
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View Lastest Price from 2,4-DIMETHYL-3-PYRROLEPROPIONIC ACID manufacturers

Career Henan Chemical Co
Product
2,4-DIMETHYL-3-PYRROLEPROPIONIC ACID 54474-50-9
Price
US $1.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
100kg
Release date
2020-01-14

54474-50-9, 2,4-DIMETHYL-3-PYRROLEPROPIONIC ACIDRelated Search:

8,13-DIVINYL-3,7,12,17-TETRAMETHYL-21H, 23H- PORPHINE-2, 18-DIPROPIONIC ACID COBALT(III) CHLORIDE CHLOROPHYLLIN Chlorophyll b Chlorophyll A Ethyl 2,4-dimethyl-5-(ethoxycarbonyl)-3-pyrrolepropionate BILIVERDIN DIHYDROCHLORIDE Chlorophyllin Bilirubin BACTERIOCHLOROPHYLL METHYL 5-(BENZYLOXYCARBONYL)-2,4-DIMETHYL-3-PYRROLEPROPIONATE 4-(2-CARBOXYETHYL)-3,5-DIMETHYLPYRROLE-2-CARBOXYLIC ACID, ETHYL ETHER ethyl 4-(2-methoxycarbonylethyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate UROBILIN IX HYDROCHLORIDE MN(III) PROTOPORPHYRIN IX CHLORIDE 2-BENZYL 4-(TERT-BUTYL) 3-(3-METHOXY-3-OXOPROPYL)-5-METHYL-1H-PYRROLE-2,4-DICARBOXYLATE ETHYL 3-(2-ETHOXY-2-OXOETHYL)-4-(3-ETHOXY-3-OXOPROPYL)-5-FORMYL-1H-PYRROLE-2-CARBOXYLATE SODIUM POTASSIUM COPPER CHLOROPHYLLIN METHYL-2-ACETOXYMETHYL-5-BENZYLOXY CARBONYL-4-METHYL-3-PYRROLEPROPIONATE

  • 3-(2,4-DIMETHYL-1H-PYRROL-3-YL)PROPANOIC ACID
  • 2,4-DIMETHYL-3-PYRROLEPROPIONIC ACID
  • tert-Butyl (4-aminobut-2-en-1-yl)carbamate hydrochloride
  • 1H-Pyrrole-3-propanoic acid, 2,4-dimethyl-
  • 54474-50-9
  • pharmacetical