ChemicalBook > CAS DataBase List > 4,6-DIAMINO-2-MERCAPTOPYRIMIDINE

4,6-DIAMINO-2-MERCAPTOPYRIMIDINE

Product Name: 4,6-DIAMINO-2-MERCAPTOPYRIMIDINE
CAS No.: 1004-39-3
Chemical Name: 4,6-DIAMINO-2-MERCAPTOPYRIMIDINE
Synonyms: AKOS USSH-4110073;TIMTEC-BB SBB007564;4,6-DiaMino-2-Mercapt;6-AMINO-2-THIOCYTOSINE;LABOTEST-BB LT00847993;2-Thio-6-aMinocytosine;THIO-4,6-DIAMINOPYRIMIDINE;4,6-Diamino-2-thiopyrimdine;4,6-DIAMINO-2-THIOPYRIMIDINE;4,6-DIAMINOPYRIMIDINE-2-THIOL
CBNumber: CB6104029
Molecular Formula: C4H6N4S
Formula Weight: 142.18
MOL File: 1004-39-3.mol

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4,6-DIAMINO-2-MERCAPTOPYRIMIDINE Property

Melting point:: >300 °C(lit.)
Boiling point:: 289.1±43.0 °C(Predicted)
Density: 1.78±0.1 g/cm3(Predicted)
storage temp.: Store below +30°C.
solubility: 1 M NaOH: soluble2%
pka: 11.81±0.10(Predicted)
form: Solid
color: Pale Beige to Light Brown
BRN: 124937
Stability:: Hygroscopic
InChIKey: QCAWOHUJKPKOMD-UHFFFAOYSA-N
CAS DataBase Reference: 1004-39-3(CAS DataBase Reference)
NIST Chemistry Reference: 2-Thiol-4,6-diamino-pyrimidine(1004-39-3)
EPA Substance Registry System: 2(1H)-Pyrimidinethione, 4,6-diamino- (1004-39-3)

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
WGK Germany: 3
RTECS: MB7660000
HS Code: 2933 59 95

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.14037
Product name: 4,6-Diamino-2-pyrimidinethiol
Purity: for synthesis
Packaging: 25g
Price: $170
Updated: 2025/07/31

TCI Chemical

Product number: D2063
Product name: 4,6-Diamino-2-mercaptopyrimidine
Purity: >95.0%(T)
Packaging: 25g
Price: $314
Updated: 2025/07/31

Usbiological

Product number: D3452-57
Product name: 4,6-Diamino-2-thiopyrimidine
Packaging: 5g
Price: $326
Updated: 2021/12/16

TRC

Product number: D416860
Product name: 4,6-Diamino-2-thiopyrimidine
Packaging: 50g
Price: $135
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD21454
Product name: 4,6-Diamino-2-thiopyrimidine
Packaging: 50g
Price: $145
Updated: 2021/12/16

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4,6-DIAMINO-2-MERCAPTOPYRIMIDINE Chemical Properties,Usage,Production

Chemical Properties

Brown-Grey Solid

Uses

2-Thioadenosine derivatives have been known to exhibit several pharmacological activities such as platelet aggregation inhibition and coronary vasodilation.

General Description

4,6-Diamino-2-mercaptopyrimidine hydrate on oxidation with hydrogen peroxide gives sulphinic acid.

Synthesis

17356-08-0

109-77-3

1004-39-3

Sodium methanolate (540 g, 9.98 mol) was dissolved in 2 L of methanol, followed by the sequential addition of thiourea (190 g, 2.50 mol) and malononitrile (412 g, 6.24 mol). The reaction mixture was stirred at 40 °C for 30 hours. After completion of the reaction, the mixture was cooled to room temperature and the solid was collected by filtration. The filter cake was dissolved in 3.5 L of water and the pH of the solution was adjusted with acetic acid to about 7. The solid product was collected by filtration again and dried to give 334 g of light yellow solid in 94% yield.

References

[1] Patent: CN107973798, 2018, A. Location in patent: Paragraph 0113-0114; 0119; 0122; 0123-0125; 0128
[2] Patent: CN107973832, 2018, A. Location in patent: Paragraph 0066; 0108-0125
[3] Arzneimittel-Forschung/Drug Research, 2002, vol. 52, # 11, p. 792 - 796
[4] Chemical and Pharmaceutical Bulletin, 2012, vol. 60, # 1, p. 70 - 78
[5] Patent: CN103709164, 2016, B. Location in patent: Paragraph 0034; 0086; 0106

4,6-DIAMINO-2-MERCAPTOPYRIMIDINE Preparation Products And Raw materials

Raw materials

Malononitrile Ethanol Sodium Thiourea

Preparation Products

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4,6-DIAMINO-2-MERCAPTOPYRIMIDINE Suppliers

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View Lastest Price from 4,6-DIAMINO-2-MERCAPTOPYRIMIDINE manufacturers

Honest Joy Holdings Limited

Product: 4,6-Diamino-2-mercaptopyrimidine 1004-39-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99.5%
Supply Ability: 100 tons
Release date: 2022-01-14

Dideu Industries Group Limited

Product: 4,6-DIAMINO-2-MERCAPTOPYRIMIDINE 1004-39-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-10

Career Henan Chemical Co

Product: 4,6-DIAMINO-2-MERCAPTOPYRIMIDINE 1004-39-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 25kg
Release date: 2019-07-11

1004-39-3, 4,6-DIAMINO-2-MERCAPTOPYRIMIDINERelated Search:

4,6-DIAMINO-2-METHYLMERCAPTOPYRIMIDINE 4,6-DIAMINO-2-MERCAPTOPYRIMIDINE 2,4-DIAMINO-6-MERCAPTOPYRIMIDINE 4,5-DIAMINO-6-MERCAPTOPYRIMIDINE 4,5-diamino-2-mercaptopyrimidine-6-ol 2,4-DIAMINO-6-MERCAPTOPYRIMIDINE HEMISULFATE,2,6-DIAMINO-4-PYRIMIDINETHIOL, HEMISULFATE 2,6-DIAMINO-4-PYRIMIDINETHIOL SULFATE 4,5-Diamino-2-pyrimidinethiol,4,5-DIAMINO-2-MERCAPTOPYRIMIDINE 4,6-Diaminopyrimidine 2-Mercaptopyrimidine 2-(BENZYLTHIO)PYRIMIDINE-4,6-DIAMINE 4,6-DIAMINO-2-MERCAPTOPYRIMIDINE HEMIHYDRATE N-[6-AMINO-2-(METHYLSULFANYL)PYRIMIDIN-4-YL]-N,N-DIMETHYLAMINE 4,6-DIAMINO-2-MERCAPTO-5-NITROSOPYRIMIDINE ETHYL 4-[6-[4-(AMINOCARBONYL)PIPERAZINO]-2-(METHYLSULFANYL)-4-PYRIMIDINYL]TETRAHYDRO-1(2H)-PYRAZINECARBOXYLATE AKOS BBS-00007358 AKOS USSH-4110075 4-[2-(METHYLSULFANYL)-6-(4-PHENYLPIPERAZINO)-4-PYRIMIDINYL]TETRAHYDRO-1(2H)-PYRAZINECARBOXAMIDE

2(1H)-Pyrimidinethione, 4,6-diamino-

2-Mercapto-4,6-diaminopyrimidine

4,6-diamino-2(1h)-pyrimidinethion

4,6-Diamino-2(1H)-pyrimidinethione

4,6-Diamino-2-thiopyrimdine

AKOS USSH-4110073

6-AMINO-2-THIOCYTOSINE

4,6-DIAMINO-2-MERCAPTOPYRIMIDINE

4,6-DIAMINO-2-PYRIMIDINETHIOL

4,6-DIAMINO-2-THIOPYRIMIDINE

4,6-DIAMINOPYRIMIDINE-2-THIOL

LABOTEST-BB LT00847993

4,6-DIAMINO-2-MERCAPTOPYRIMIDINE HYDRATE, 99%, WATER CA 0.5-

TIMTEC-BB SBB007564

THIO-4,6-DIAMINOPYRIMIDINE

2(1H)-Pyrimidinethione, 4,6-diamino- (7CI,9CI)

4,6-DIAMINO-2-MERCAPTOPYRIMIDINE HYDRATE , WATER CA 0.5-1 MOL

4,6-Diamino-2-mercaptopyrimidine hydrate, 98+%

4,6-Diaminopyrimidine-2-thiol ,98%

4,6-Diamino-2-mercaptopyrimidine hydrate, 99%, water ca 0.5-1 mol

4,6-Diamino-2-mercaptopyrimidine hemihydrate, 98+%

4,6-Diaminopyrimidine-2(1H)-thione

2-Thio-6-aMinocytosine

4,6-DiaMino-1,2-dihydro-2-thioxopyriMidine

4,6-DiaMino-1H-pyriMidine-2-thione

4,6-DiaMino-2-Mercapt

4,6-DIAMINO-2-PYRIMIDINETHIOL FOR SYNTHE

4,6-Diamino-2-sulphanylpyrimidine

4,6-Diaminopyrimidine-2-thiol, 4,6-Diamino-2-mercaptopyrimidine, 4,6-Diaminopyrimidine-2(1H)-thione

4,6-Diamino-2-pyrimidinethiol for synthesis

4,6-diamino-1H-pyrimidine-2-thione hydrate

4,6-Diamino-2-mercaptopyrimidine&gt

4,6-DIAMINO-2-MERCAPTOPYRIMIDINE ISO 9001：2015 REACH

1004-39-3

C8H14N8OS2

C4H6N4SH2O

Heterocyclic Building Blocks

Pyrimidines

Building Blocks

C4 to C5

Chemical Synthesis

Heterocyclic Building Blocks

Pyrimidines

Bases & Related Reagents

Inhibitors

Nucleotides

Sulfur & Selenium Compounds

Nucleotides and Nucleosides

PYRIMIDINE

APIs & Intermediate