2-PIPERAZIN-1-YL-BENZOIC ACID METHYL ESTER
- Product Name
- 2-PIPERAZIN-1-YL-BENZOIC ACID METHYL ESTER
- CAS No.
- 159974-63-7
- Chemical Name
- 2-PIPERAZIN-1-YL-BENZOIC ACID METHYL ESTER
- Synonyms
- Methyl 2-(piperazin-1-yl)benzoate;methyl 2-(piperazin-1-yl)benzoate-HCl;2-PIPERAZIN-1-YL-BENZOIC ACID METHYL ESTER;Benzoic acid, 2-(1-piperazinyl)-, methyl ester
- CBNumber
- CB6104478
- Molecular Formula
- C12H16N2O2
- Formula Weight
- 220.27
- MOL File
- 159974-63-7.mol
2-PIPERAZIN-1-YL-BENZOIC ACID METHYL ESTER Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M726178
- Product name
- Methyl2-(piperazin-1-yl)benzoate
- Packaging
- 500mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- Z4235
- Product name
- Methyl2-(piperazin-1-yl)benzoate
- Packaging
- 250mg
- Price
- $157
- Updated
- 2021/12/16
- Product number
- CHM0092544
- Product name
- 2-PIPERAZIN-1-YL-BENZOIC ACID METHYL ESTER
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $2304.23
- Updated
- 2021/12/16
- Product number
- A198030
- Product name
- Methyl2-(piperazin-1-yl)benzoate
- Purity
- 95%
- Packaging
- 100mg
- Price
- $43
- Updated
- 2021/12/16
- Product number
- A198030
- Product name
- Methyl2-(piperazin-1-yl)benzoate
- Purity
- 95%
- Packaging
- 250mg
- Price
- $65
- Updated
- 2021/12/16
2-PIPERAZIN-1-YL-BENZOIC ACID METHYL ESTER Chemical Properties,Usage,Production
Synthesis
67-56-1
446831-27-2
159974-63-7
Example 2: Synthesis of 2-{4-[2-(3,5-dimethyl-pyrazol-1-yl)-acetyl]-piperazin-1-yl}-N-pyridin-4-yl-benzamide 1. 2-(Piperazin-1-yl)benzoic acid (1.000 g, 4.89 mmol) was suspended in 10 mL of methanol. 2. 5 mL of concentrated sulfuric acid was slowly added to the suspension. 3. The reaction mixture was stirred for 16 h. A white precipitate was observed. 4. 5 mL of concentrated sulfuric acid and 10 mL of methanol were added. 5. The reaction volume was expanded by adding 200 mL of methanol and 60 mL of concentrated sulfuric acid and the mixture was continued to be stirred for 2 hours. 6. Heat the reaction mixture to reflux and maintain for 12 hours. 7. Concentrate the reaction volume to about 175mL. 8. The concentrated mixture was upsampled to an ion exchange column and eluted with 5 x 200mL of 10% ammonia/methanol solution. 9. The product eluate was collected and concentrated. 10. The concentrate was co-evaporated with toluene to remove residual water to give 0.667 g of methyl 2-piperazin-1-yl-benzoate in 63% yield.
References
[1] Patent: WO2010/126851, 2010, A1. Location in patent: Page/Page column 86
[2] Patent: WO2010/126811, 2010, A1. Location in patent: Page/Page column 142-143
2-PIPERAZIN-1-YL-BENZOIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
2-PIPERAZIN-1-YL-BENZOIC ACID METHYL ESTER Suppliers
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- Please Send Email 18652950785
- Fax
- 025-87193546
- chemweiao@163.com
- Country
- China
- ProdList
- 4378
- Advantage
- 65
- Tel
- 021-60343070
- Fax
- 021-35122006
- Country
- China
- ProdList
- 12740
- Advantage
- 55
- Tel
- 18860950986
- tangmanman@zenjipharma.com
- Country
- China
- ProdList
- 1733
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 021-61317773
- Fax
- 021-61486878
- sales@aspirebio.com
- Country
- China
- ProdList
- 2880
- Advantage
- 58
- Tel
- 021-60345187 13671753212
- Fax
- 021-34702061
- lzz841106@aliyun.com
- Country
- China
- ProdList
- 10263
- Advantage
- 55
- Tel
- 微信 17321281695 18019252918
- Fax
- 17321281695
- sale@amkchem.com
- Country
- China
- ProdList
- 15136
- Advantage
- 55
- Tel
- 13598610367
- Fax
- QQ:2468833170
- 2841375912@qq.com
- Country
- China
- ProdList
- 2786
- Advantage
- 52
- Tel
- 025-66028182 18626450290
- yftan@aikonchem.com
- Country
- China
- ProdList
- 16679
- Advantage
- 50
View Lastest Price from 2-PIPERAZIN-1-YL-BENZOIC ACID METHYL ESTER manufacturers
- Product
- 2-PIPERAZIN-1-YL-BENZOIC ACID METHYL ESTER 159974-63-7
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-01-12