Benzoic acid, 3-amino-5-ethoxy-, methyl ester (9CI)
- Product Name
- Benzoic acid, 3-amino-5-ethoxy-, methyl ester (9CI)
- CAS No.
- 706792-04-3
- Chemical Name
- Benzoic acid, 3-amino-5-ethoxy-, methyl ester (9CI)
- Synonyms
- Methyl 3-amino-5-ethoxybenzoate;3-Amino-5-ethoxybenzoic acid methyl ester;Bnzoic acid, 3-amino-5-ethoxy-, methyl ester;Benzoic acid, 3-amino-5-ethoxy-, methyl ester;Benzoic acid, 3-amino-5-ethoxy-, methyl ester (9CI)
- CBNumber
- CB61070826
- Molecular Formula
- C10H13NO3
- Formula Weight
- 195.22
- MOL File
- 706792-04-3.mol
Benzoic acid, 3-amino-5-ethoxy-, methyl ester (9CI) Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
Safety
- HS Code
- 2922500090
N-Bromosuccinimide Price
- Product number
- 7338DF
- Product name
- Methyl3-amino-5-ethoxybenzoate
- Packaging
- 10g
- Price
- $154
- Updated
- 2021/12/16
- Product number
- A116460
- Product name
- Methyl3-amino-5-ethoxybenzoate
- Purity
- 98%
- Packaging
- 25g
- Price
- $161
- Updated
- 2021/12/16
- Product number
- 61-11633
- Product name
- Methyl3-amino-5-ethoxybenzoate
- Purity
- 95-98%
- Packaging
- 1g
- Price
- $180
- Updated
- 2021/12/16
- Product number
- CM153636
- Product name
- methyl3-amino-5-ethoxybenzoate
- Purity
- 95+%
- Packaging
- 5g
- Price
- $184
- Updated
- 2021/12/16
- Product number
- CM153636
- Product name
- methyl3-amino-5-ethoxybenzoate
- Purity
- 95+%
- Packaging
- 10g
- Price
- $281
- Updated
- 2021/12/16
Benzoic acid, 3-amino-5-ethoxy-, methyl ester (9CI) Chemical Properties,Usage,Production
Synthesis
1375150-03-0
706792-04-3
General procedure for the synthesis of methyl 3-amino-5-ethoxybenzoate from methyl 3-ethoxy-5-nitrobenzoate: to methyl 3-ethoxy-5-nitrobenzoate (6.1 kg, 27.1 mol) prepared in step 2, methanol (54 L) and purified water (54 L) were added, followed by 10% palladium/carbon catalyst (6.1 kg, 10% wt/wt) . The reaction was carried out at room temperature with stirring in a hydrogen atmosphere at 4 atmospheres for 2.5 hours. Upon completion of the reaction, acetone (54 L) was added to dilute the reaction mixture, followed by removal of the 10% palladium/carbon catalyst by filtration. Methanol and acetone were removed by distillation under reduced pressure. The resulting solid was filtered and washed with pure water to give the final methyl 3-amino-5-ethoxybenzoate (4.88 kg, 92.2% yield, yellow solid). The product was characterized by 1H-NMR (400 MHz, CDCl3) with the following chemical shifts: δ 6.95 (s, 2H), 6.39 (s, 1H), 4.01 (q, J=6.8Hz, 2H), 3.87 (s, 3H), 3.76 (s, 2H), 1.38 (t, J=6.8Hz, 3H).
References
[1] Patent: US2014/350007, 2014, A1. Location in patent: Paragraph 0082; 0083; 0084
[2] Patent: WO2003/106405, 2003, A1. Location in patent: Page 204-208
Benzoic acid, 3-amino-5-ethoxy-, methyl ester (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
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