2,4-DICHLORO-3-CYANOPYRIDINE

Product Name: 2,4-DICHLORO-3-CYANOPYRIDINE
CAS No.: 180995-12-4
Chemical Name: 2,4-DICHLORO-3-CYANOPYRIDINE
Synonyms: 2,4-Dichloronicotinonitrile;2,4-Dichlorocarbonitrile;3-Cyano-2,4-dichloropyridine;2,4-DICHLORO-3-CYANOPYRIDINE;2,4-Dichloro-3-cyanopyridine,95%;2,4-dichloro-3-Pyridinecarbonitrile;2,4-Dichloropyridine-3-carbonitrile;3-Pyridinecarbonitrile, 2,4-dichloro-;2,4-DICHLORO-3-CYANOPYRIDINE ISO 9001：2015 REACH
CBNumber: CB61076000
Molecular Formula: C6H2Cl2N2
Formula Weight: 173
MOL File: 180995-12-4.mol

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2,4-DICHLORO-3-CYANOPYRIDINE Property

Boiling point:: 293.0±35.0 °C(Predicted)
Density: 1.49±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: -1.94±0.10(Predicted)
Appearance: White to light brown Solid
Water Solubility: Slightly soluble in water.

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Safety

RIDADR: 3439
HazardClass: 6.1
PackingGroup: Ⅲ
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: D436065
Product name: 2,4-Dichloro-3-cyanopyridine
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: D436065
Product name: 2,4-Dichloro-3-cyanopyridine
Packaging: 500mg
Price: $65
Updated: 2021/12/16

TRC

Product number: D436065
Product name: 2,4-Dichloro-3-cyanopyridine
Packaging: 1g
Price: $90
Updated: 2021/12/16

AK Scientific

Product number: W3932
Product name: 2,4-Dichloro-3-cyanopyridine
Packaging: 1g
Price: $66
Updated: 2021/12/16

AK Scientific

Product number: J99671
Product name: 2,4-Dichloro-3-cyanopyridine
Packaging: 5g
Price: $150
Updated: 2021/12/16

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2,4-DICHLORO-3-CYANOPYRIDINE Chemical Properties,Usage,Production

Uses

2,4-Dichloro-3-cyanopyridine, is used as a pharmaceutical intermediate.

Synthesis

869802-74-4

180995-12-4

General procedure for the synthesis of 2,4-dichloro-3-cyanopyridine from 2-chloro-4-hydroxynicotinonitrile: 1. 2-Chloro-4-oxo-1,4-dihydropyridine-3-carbonitrile (238 mg, 1.54 mmol) was dissolved in phosphorochloridic acid (0.7 mL) and heated to reflux for 2 hours. 2. After the reaction was completed, the reaction solution was concentrated and aqueous sodium bicarbonate (10 mL) was added to the residue. 3. The aqueous phase was extracted twice with ethyl acetate (10 mL), the organic phases were combined and dried over sodium sulfate. 4. The organic solvent was removed by pressurized distillation, and the crude product was obtained. 5. The crude product was recrystallized in hexane to give 2,4-dichloro-3-cyanopyridine (167 mg, 63% yield). Product characterization: - Appearance: white powder - Melting point: 107-109°C - IR (KBr) νmax: 3072, 2235, 1559, 1538, 1444, 1406, 1368, 1220, 820 cm?1 - 1H NMR (DMSO-d6, 400 MHz) δ: 7.91 (1H, d, J = 5.5 Hz), 8.65 (1H, d, J = 5.5 Hz) - HRMS m/z calculated value C6H2N2Cl2: 171.9595, measured value: 171.9598 - MS (EI) m/z: 172 [M?], 137, 110, 101, 75, 62, 51

References

[1] Patent: EP1764367, 2007, A1. Location in patent: Page/Page column 143

2,4-DICHLORO-3-CYANOPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4-DICHLORO-3-CYANOPYRIDINE Suppliers

China 115 Germany 1 India 2 Switzerland 2 United Kingdom 1 United States 13 Global 134

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Tetranov Biopharm

Tel: 13526569071
Email: sales@leadmedpharm.com
Country: China
ProdList: 7892
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

shanghai Rainbow MediTech.Co.Ltd.

Tel: 021-64968085,64968086-5815,5812; 13472757003
Fax: +86 21 64968087
Email: xiaoxia.zeng@rainbowpharma.cn
Country: China
ProdList: 961
Advantage: 65

Record Tech (Shanghai) Co., LTD

Tel: 13761627472
Fax: 86-21-64965863
Email: 183009664@qq.com
Country: China
ProdList: 649
Advantage: 62

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
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Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

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View Lastest Price from 2,4-DICHLORO-3-CYANOPYRIDINE manufacturers

PNP Biotech Co. Ltd

Product: 2,4-Dichloronicotinonitrile 180995-12-4
Price: US $0.00/kg
Min. Order: 25kg
Purity: 98%
Supply Ability: Inquiry
Release date: 2023-07-12

Dideu Industries Group Limited

Product: 2,4-DICHLORO-3-CYANOPYRIDINE 180995-12-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-15

Career Henan Chemical Co

Product: 2,4-DICHLORO-3-CYANOPYRIDINE 180995-12-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-30

180995-12-4, 2,4-DICHLORO-3-CYANOPYRIDINERelated Search:

Clopyralid 2,3-Dichloropyridine Dichloropyridine 3,5-DICHLORO-2-CYANOPYRIDINE 2,6-Dichloro-3-Cyanopyridine 2,4,5,6-TETRACHLORO-NICOTINONITRILE 2,4-DICHLORO-3-CYANOPYRIDINE 3-AMINO-2,6-DICHLORO-4-CYANOPYRIDINE AURORA KA-4136 4-(3,4,6-TRICHLORO-5-CYANOPYRIDIN-2-YL)-N-[3-(TRIFLUOROMETHYL)PHENYL]PIPERAZINE-1-CARBOXAMIDE 2-(3,4,6-TRICHLORO-5-CYANOPYRIDIN-2-YL)-N-[3-(TRIFLUOROMETHYL)PHENYL]HYDRAZINECARBOXAMIDE N-PHENYL-2-(3,4,6-TRICHLORO-5-CYANOPYRIDIN-2-YL)HYDRAZINECARBOTHIOAMIDE 2,4,5-TRICHLORO-6-({2-[(3,3,3-TRIFLUOROPROPYL)THIO]PHENYL}AMINO)NICOTINONITRILE 2,4-DICHLORO-3-CYANO-5-FLUORO PYRIDINE 4-(3,4,6-TRICHLORO-5-CYANOPYRIDIN-2-YL)-N-{4-[(TRIFLUOROMETHYL)THIO]PHENYL}PIPERAZINE-1-CARBOTHIOAMIDE N-{[2-CHLORO-5-(TRIFLUOROMETHYL)PHENYL]SULFONYL}-4-(3,4,6-TRICHLORO-5-CYANOPYRIDIN-2-YL)PIPERAZINE-1-CARBOXAMIDE 2,4,5-TRICHLORO-6-{[2-(3,3,3-TRIFLUOROPROPOXY)PHENYL]AMINO}NICOTINONITRILE

2,4-DICHLORO-3-CYANOPYRIDINE

3-Cyano-2,4-dichloropyridine

2,4-Dichloronicotinonitrile

2,4-Dichlorocarbonitrile

2,4-Dichloropyridine-3-carbonitrile

2,4-dichloro-3-Pyridinecarbonitrile

3-Pyridinecarbonitrile, 2,4-dichloro-

2,4-Dichloro-3-cyanopyridine,95%

2,4-DICHLORO-3-CYANOPYRIDINE ISO 9001：2015 REACH

180995-12-4

Pyridine

Heterocycle-Pyridine series