5-Hydroxybenzo[b]furan
- Product Name
- 5-Hydroxybenzo[b]furan
- CAS No.
- 13196-10-6
- Chemical Name
- 5-Hydroxybenzo[b]furan
- Synonyms
- 5-BENZOFURANOL;Benzofuran-5-ol;1-benzofuran-5-ol;Benzo[b]furan-5-ol;5-Hydroxybenzofuran;5-HYDROXYBENZOFURAZAN;5-Hydroxybenzo[b]furan
- CBNumber
- CB61092871
- Molecular Formula
- C8H6O2
- Formula Weight
- 134.13
- MOL File
- 13196-10-6.mol
5-Hydroxybenzo[b]furan Property
- Melting point:
- 186-187℃
- Boiling point:
- 247.1±13.0 °C(Predicted)
- Density
- 1.280±0.06 g/cm3(Predicted)
- storage temp.
- RT, stored under nitrogen
- form
- solid
- pka
- 9.27±0.40(Predicted)
- color
- White
Safety
- HS Code
- 2932990090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B421235
- Product name
- Benzofuran-5-ol
- Packaging
- 50mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- B421235
- Product name
- Benzofuran-5-ol
- Packaging
- 100mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- FB30680
- Product name
- 5-Benzofuranol
- Packaging
- 50mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- OR42004
- Product name
- 5-Hydroxybenzo[b]furan
- Packaging
- 250mg
- Price
- $138
- Updated
- 2021/12/16
- Product number
- FB30680
- Product name
- 5-Benzofuranol
- Packaging
- 100mg
- Price
- $150
- Updated
- 2021/12/16
5-Hydroxybenzo[b]furan Chemical Properties,Usage,Production
Uses
5-Hydroxybenzo[b]furan (Benzofuran-5-ol) is used in the preparation of conductive polymer complexes, optoelectronic materials, and the synthesis of biological inhibitors.
Synthesis
13391-28-1
13196-10-6
GENERAL STEPS: 5-methoxybenzofuran (0.5 g, 3.37 mmol) was dissolved in dichloromethane (DCM, 7 mL) under ice-bath cooling conditions and boron tribromide (3.4 mL, 3.37 mmol, 1 M DCM solution) was added slowly. The reaction mixture was stirred at 0 °C for 1 h. An equal amount of boron tribromide (3.4 mL) was added again. Subsequently, the reaction mixture was brought to room temperature and stirring was continued for 2 hours. The progress of the reaction was monitored by thin layer chromatography (TLC) and after confirming the completion of the reaction, the reaction mixture was slowly poured into ice water and the pH was adjusted with sodium carbonate (Na2CO3) to 7. The aqueous phase was extracted with dichloromethane (DCM, 2×), the organic phases were combined and washed with saturated brine, dried over anhydrous sodium sulphate (Na2SO4) and concentrated under reduced pressure. The resulting light brown solid product (0.36 g, yield 79.6%) was pure enough to meet the requirements of the subsequent reaction and did not require further purification. The structure of the product was confirmed by 1H NMR (400 MHz, CD3OD): δ 7.59 (d, J = 2.0 Hz, 1H), 7.35 (d, J = 9.2 Hz, 1H), 7.01 (d, J = 2.4 Hz, 1H), 6.82 (dd, J = 8.8 Hz, J = 2.8 Hz, 1H), 6.67 (m, 1H), 4.73 (s 1H).
References
[1] Chemical Communications, 2016, vol. 52, # 16, p. 3348 - 3351
[2] Synthetic Communications, 2006, vol. 36, # 14, p. 1983 - 1990
[3] Patent: WO2007/61458, 2007, A2. Location in patent: Page/Page column 43; 91
[4] Patent: WO2017/87965, 2017, A1. Location in patent: Page/Page column 23
[5] Patent: WO2018/13774, 2018, A1. Location in patent: Page/Page column 379; 380
5-Hydroxybenzo[b]furan Preparation Products And Raw materials
Raw materials
Preparation Products
5-Hydroxybenzo[b]furan Suppliers
- Tel
- 18032852911
- 2701131818@qq.com
- Country
- China
- ProdList
- 57
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 0086-21-58956006
- Fax
- 0086-21-58956100
- Country
- China
- ProdList
- 7811
- Advantage
- 57
- Tel
- +86 (25) 5860-8846
- Fax
- +86 (25) 5860-8846
- kt_chem@126.com
- Country
- China
- ProdList
- 218
- Advantage
- 62
- Tel
- 021-61551611 13296011611
- Fax
- ＋86 21-50676805
- contact@trustwe.com
- Country
- China
- ProdList
- 9895
- Advantage
- 58
- Tel
- 021-37910092; 15821801668
- Fax
- 021-37910267
- cong44@126.com
- Country
- China
- ProdList
- 293
- Advantage
- 58
- Tel
- 0512-56316828 4008675858
- Fax
- +86-512-56316826
- sales@amateksci.com
- Country
- China
- ProdList
- 9874
- Advantage
- 55
- Tel
- +49 5662 408730
- Fax
- +49 5662 4087320
- info@synchem.de
- Country
- Germany
- ProdList
- 4705
- Advantage
- 70
- Tel
- 010-56330744 18310155299
- Fax
- 010-56330744
- sales@labter.com.cn
- Country
- China
- ProdList
- 20000
- Advantage
- 55
- Tel
- +86-2332782371 +86-18120098618
- sales@adobechem.com
- Country
- China
- ProdList
- 1250
- Advantage
- 50
View Lastest Price from 5-Hydroxybenzo[b]furan manufacturers
- Product
- 5-Hydroxybenzofuran 13196-10-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
- Product
- 5-BENZOFURANOL 13196-10-6
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2018-12-23