ChemicalBook > CAS DataBase List > Polyprenic

Polyprenic

Product Name
Polyprenic
CAS No.
81485-25-8
Chemical Name
Polyprenic
Synonyms
E-5166;NIK-333;Polyprenic;POLYPRENOICACID;Peretinoin (NIK-333;NIK-333;NIK333;NIK 333;Peretinoin, 10 mM in DMSO;4,5-Dehydrogeranylgeranoic acid;4,5-Didehydrogeranylgeranoic acid;3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid
CBNumber
CB61179550
Molecular Formula
C20H30O2
Formula Weight
302.45
MOL File
81485-25-8.mol
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Polyprenic Property

Boiling point:
460.3±24.0 °C(Predicted)
Density 
0.943±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Acetonitrile (Slightly, Heated), Benzene (Slightly), Chloroform (Slightly)
pka
4.79±0.33(Predicted)
form 
Solid
color 
Pale Brown to Orange
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC
Product number
P286120
Product name
Peretinoin
Packaging
5mg
Price
$215
Updated
2021/12/16
ChemScene
Product number
CS-5529
Product name
Peretinoin
Purity
99.79%
Packaging
5mg
Price
$252
Updated
2021/12/16
ChemScene
Product number
CS-5529
Product name
Peretinoin
Purity
99.79%
Packaging
10mg
Price
$420
Updated
2021/12/16
AK Scientific
Product number
3260BB
Product name
Peretinoin
Packaging
100mg
Price
$456
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0015454
Product name
PERETINOIN
Purity
95.00%
Packaging
5MG
Price
$496.36
Updated
2021/12/16
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Polyprenic Chemical Properties,Usage,Production

Uses

Peretinoin is an acyclic retinoid that may have the ability to inhibit hepatic carcinogenesis

Biological Activity

Peretinoin is an orally active synthetic acyclic retinoid (ACR) whose in vivo anti-hepatocellular carcinoma (HCC) efficacy is attributed to its upregulatory activity toward retinoid nuclear receptors (RARbeta & RXRalpha), as well as negative regulation against sphingosine kinase 1 (SPHK1) expression and, thereby, sphingosine metabolic pathway. Peretinoin inhibits the replication of hepatitis B & C viruses in cultures (HBV & HCV EC50 = 9-25 μM) and shows in vivo efficacy in rodent models of hepatocarcinogenesis among rats (10, 40, or 80 mg/kg/day p.o.) and mice (0.03% or 0.06% in diet) subjected to chronic inflammation induction by diethylnitrosamine (DEN).

Polyprenic Preparation Products And Raw materials

Raw materials

Preparation Products

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Polyprenic Suppliers

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View Lastest Price from Polyprenic manufacturers

Career Henan Chemica Co
Product
Polyprenic 81485-25-8
Price
US $8.00/KG
Min. Order
1g
Purity
Min98% HPLC/GC
Supply Ability
g/kg/ton
Release date
2020-10-27

81485-25-8, PolyprenicRelated Search:


  • Polyprenic
  • 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid
  • POLYPRENOICACID
  • (2E,4E,6E,10E)-3,7,11,15-Tetramethyl-2,4,6,10,14-hexadecapentaenoic acid
  • 4,5-Dehydrogeranylgeranoic acid
  • 4,5-Didehydrogeranylgeranoic acid
  • E-5166
  • NIK-333
  • 2,4,6,10,14-Hexadecapentaenoicacid, 3,7,11,15-tetraMethyl-, (2E,4E,6E,10E)-
  • (2E,4E,6E,10E)-3,7,11,15-tetraMethyl hexadeca-2,4,6,10,14-pentaenoic acid
  • all-trans-3,7,11,15-Tetramethyl-2,4,6,10,14-hexadecapentaenoic acid
  • NIK-333;NIK333;NIK 333
  • inhibit,NIK-333,NIK 333,Retinoic acid receptors,SphK,Peretinoin,Retinoid X receptors,HCV,Inhibitor,Autophagy,Sphingosine kinase,Hepatitis C virus,RAR/RXR
  • Peretinoin, 10 mM in DMSO
  • Peretinoin (NIK-333
  • 81485-25-8