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Remikiren

Product Name
Remikiren
CAS No.
126222-34-2
Chemical Name
Remikiren
Synonyms
D09038;C07465;AC1O44IV;Remikiren;Ro-42-5892;CHEMBL31601;(αS)-α-[[(S)-2-(tert-Butylsulfonylmethyl)-1-oxo-3-phenylpropyl]amino]-N-[(1S,2R,3S)-1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]-1H-imidazole-4-propanamide;1H-Imidazole-5-propanamide, N-[(1S,2R,3S)-1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]-α-[[(2S)-2-[[(1,1-dimethylethyl)sulfonyl]methyl]-1-oxo-3-phenylpropyl]amino]-, (αS)-
CBNumber
CB61179651
Molecular Formula
C33H50N4O6S
Formula Weight
630.846
MOL File
126222-34-2.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
R143552
Product name
Remikiren-d4
Packaging
5mg
Price
$13750
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007326
Product name
REMIKIREN
Purity
95.00%
Packaging
5MG
Price
$501.97
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
61568
Product name
Remikiren
Packaging
10mg
Price
$13500
Updated
2021/12/16
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Remikiren Chemical Properties,Usage,Production

Uses

Remikiren, is a renin inhibitor under development for the treatment of hypertension (high blood pressure).

Definition

ChEBI: Remikiren is an L-histidine derivative that is L-histidine in which one of the amino hydrogens is replaced by a (2S)-2-[(2-methylpropane-2-sulfonyl)methyl]-3-phenylpropanoyl group and the carboxy group is replaced by a [(2S,3R,4S)-1-cyclohexyl-4-cyclopropyl-3,4-dihydroxybutan-2-yl]amino group. It is a renin inhibitor which was under development for the treatment of hypertension (now discontinued). It has a role as an antihypertensive agent, a vasodilator agent, a peptidomimetic and an EC 3.4.23.15 (renin) inhibitor. It is a sulfone, a diol, a secondary carboxamide, a member of cyclopropanes and a L-histidine derivative.

Remikiren Preparation Products And Raw materials

Raw materials

Preparation Products

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126222-34-2, RemikirenRelated Search:


  • (αS)-α-[[(S)-2-(tert-Butylsulfonylmethyl)-1-oxo-3-phenylpropyl]amino]-N-[(1S,2R,3S)-1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]-1H-imidazole-4-propanamide
  • Ro-42-5892
  • C07465
  • Remikiren
  • 1H-Imidazole-5-propanamide, N-[(1S,2R,3S)-1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]-α-[[(2S)-2-[[(1,1-dimethylethyl)sulfonyl]methyl]-1-oxo-3-phenylpropyl]amino]-, (αS)-
  • AC1O44IV
  • CHEMBL31601
  • D09038
  • 126222-34-2
  • C33H50N4O6S