ChemicalBook > CAS DataBase List > (4S,6S)-4H-Thieno[2,3-b]-thiopyran-4-ol-5,6-dihydro-6-methyl-7,7-dioxide

(4S,6S)-4H-Thieno[2,3-b]-thiopyran-4-ol-5,6-dihydro-6-methyl-7,7-dioxide

Product Name
(4S,6S)-4H-Thieno[2,3-b]-thiopyran-4-ol-5,6-dihydro-6-methyl-7,7-dioxide
CAS No.
147128-77-6
Chemical Name
(4S,6S)-4H-Thieno[2,3-b]-thiopyran-4-ol-5,6-dihydro-6-methyl-7,7-dioxide
Synonyms
Dorzolamide N-2;Dorzolamide Impurity 2;Tizanidine Impurity 14;Dorzolamide Impurity 17;Dorzolamide Impurity 28;(4R,6S)-5,6-Dihydro-4-hydroxy-6-Methyl thieno2,3-b;(4S,6S)-4H-Thieno[2,3-b]-thiopyran-4-ol-5,6-dihydro-6-methyl...;(4R,6S)-6-Methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol;(4R,6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol 7,7-dioxide;(4R,6R)-6-Methyl-5,6-dihydro-4H-thieno-[2,3-b]thiopyran-4-ol 7,7-dioxide
CBNumber
CB61180116
Molecular Formula
C8H10O3S2
Formula Weight
218.29
MOL File
147128-77-6.mol
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(4S,6S)-4H-Thieno[2,3-b]-thiopyran-4-ol-5,6-dihydro-6-methyl-7,7-dioxide Property

Melting point:
154-155 °C
Boiling point:
433.3±45.0 °C(Predicted)
Density 
1.462
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Sparingly), DMSO, Ethyl Acetate
pka
13.06±0.40(Predicted)
form 
Solid
color 
White to Off-White
InChI
InChI=1S/C8H10O3S2/c1-5-4-7(9)6-2-3-12-8(6)13(5,10)11/h2-3,5,7,9H,4H2,1H3/t5-,7+/m0/s1
InChIKey
NFUQUGUUAUVBMO-CAHLUQPWSA-N
SMILES
C12SC=CC=1[C@H](O)C[C@H](C)S2(=O)=O
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Safety

HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
T344510
Product name
(4R,6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol7,7-Dioxide
Packaging
5g
Price
$150
Updated
2021/12/16
TRC
Product number
T344510
Product name
(4R,6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol7,7-Dioxide
Packaging
25g
Price
$375
Updated
2021/12/16
Apolloscientific
Product number
OR350339
Product name
(4R,6S)-6-Methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol
Packaging
5g
Price
$421
Updated
2021/12/16
SynQuest Laboratories
Product number
6H66-1-70
Product name
(4R,6S)-6-Methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol
Packaging
5G
Price
$464
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD43179
Product name
(4R,6S)-5,6-Dihydro-4-hydroxy-6-methylthieno[2,3-b]thiopyran-7,7-dioxide
Packaging
25g
Price
$480
Updated
2021/12/16
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(4S,6S)-4H-Thieno[2,3-b]-thiopyran-4-ol-5,6-dihydro-6-methyl-7,7-dioxide Chemical Properties,Usage,Production

Uses

(4R,6S)-4H-Thieno[2,3-b]thiopyran-4-ol, 5,6-dihydro-6-methyl-,7,7-dioxide is an analog of topically-active carbonic anhydrase inhibitor MK-507 also commonly known as Dorzolamide (D535100).

(4S,6S)-4H-Thieno[2,3-b]-thiopyran-4-ol-5,6-dihydro-6-methyl-7,7-dioxide Preparation Products And Raw materials

Raw materials

Preparation Products

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(4S,6S)-4H-Thieno[2,3-b]-thiopyran-4-ol-5,6-dihydro-6-methyl-7,7-dioxide Suppliers

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View Lastest Price from (4S,6S)-4H-Thieno[2,3-b]-thiopyran-4-ol-5,6-dihydro-6-methyl-7,7-dioxide manufacturers

Career Henan Chemical Co
Product
(4S,6S)-4H-Thieno[2,3-b]-thiopyran-4-ol-5,6-dihydro-6-methyl-7,7-dioxide 147128-77-6
Price
US $8.80/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
100kg
Release date
2019-07-04

147128-77-6, (4S,6S)-4H-Thieno[2,3-b]-thiopyran-4-ol-5,6-dihydro-6-methyl-7,7-dioxideRelated Search:

5,6-Dihydro-4-hydroxy-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide DorzolaMide Dorzolamide Impurity 32 dorzolamide Dorzolamide Impurity 3 rac-cis Dorzolamide (4S,6S)-5,6-Dihydro-4-hydroxy-6-Methylthieno[2,3-b]thiopyran-7,7-dioxide Dorzolamide Impurity 27 N-Deethyl DorzolaMide Hydrochloride (4S)-4-Acetamide-5,6-Dihydro-6-Methyl-2-Sulfonamide-Thio[2,3-B]Thiopyran7,7Dioxide Dorzolamide Dorzolamide N-Sulfonamide Dimer N-[(4S,6S)-6-METHYL-7,7-DIOXO-5,6-DIHYDRO-4H-THIENO[2,3-B]THIOPYRAN-4-YL]ACETAMIDE Dorzolamide EP Impurity A HCl Dorzolamide Hydrochloride 4H-Thieno[2,3-b]thiopyran-4-amine,N-ethyl-5,6-dihydro-6-methyl-, 7,7-dioxide, (4S,6S) N-Deethyl Dorzolamide Dorzolamide Impurity 5

  • (4S,6S)-4H-Thieno[2,3-b]-thiopyran-4-ol-5,6-dihydro-6-methyl-7,7-dioxide
  • 4H-THIENO[2,3-B]THIOPYRAN-4-OL, 5,6-DIHYDRO-6-METHYL-, 7,7-DIOXIDE, (4S,6S)
  • (4R,6S)-5,6-Dihydro-4-hydroxy-6-methylthieno[2,3-b]thiopyran-7,7-dioxide
  • (4R,6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol 7,7-dioxide
  • 5,6-Dihydro-(R,S)-4-acetoxy-(S)-6-methy1 -4H-thieno[2,3-b]thiopyran 7,7-dioxide
  • (4R,6S)-6-Methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol
  • (4R,6S)-5,6-dihydro-6-Methyl-4H-thieno[2,3-b]thiopyran-4-ol,7,7,-dioxide&nbsp
  • (4R,6S)-5,6-Dihydro-4-hydroxy-6-Methyl thieno2,3-b
  • (4R,6R)-6-Methyl-5,6-dihydro-4H-thieno-[2,3-b]thiopyran-4-ol 7,7-dioxide
  • (4R,6S)-4-Hydroxy-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran 7,7-dioxide
  • 4H-Thieno[2,3-b]thiopyran-4-ol, 5,6-dihydro-6-methyl-, 7,7-dioxide, (4R,6S)-
  • Dorzolamide N-2
  • 5,6-Dihydro-(R)-4-hydrox-(S)-6-methyl- 4H-thieno[2,3-b] thiopyran-7,7-Dioxide
  • (4S,6S)-4H-Thieno[2,3-b]-thiopyran-4-ol-5,6-dihydro-6-methyl-7,7-dioxide,Dorzolamide intermediate
  • Dorzolamide Impurity 17
  • Dorzolamide Impurity 2
  • Dorzolamide Impurity 28
  • (4S,6S)-4H-Thieno[2,3-b]-thiopyran-4-ol-5,6-dihydro-6-methyl...
  • C8H10O3S2 (4S,6S)-4H-Thieno[2,3-b]-thiopyran-4-ol-5,6-dihydro-6-methyl-7,7-dioxide 147128-77-6
  • (4R,6S)-4-HYDROXY-6-METHYL-5,6-DIHYDRO-4H-THIENO[2,3-B]THIOPYRAN-7,7-DIOXIDE (CHIRAL SULFONE)
  • Tizanidine Impurity 14
  • 147128-77-6
  • C9H14O3S2