1-Propanol, 2-methyl-2-(methylamino)-
- Product Name
- 1-Propanol, 2-methyl-2-(methylamino)-
- CAS No.
- 27646-80-6
- Chemical Name
- 1-Propanol, 2-methyl-2-(methylamino)-
- Synonyms
- empty;NSC 147612;2-Methyl-2-methylaminopropan-1-ol;2-Methyl-2-(methylamino)propan-1-o;2-(METHYLAMINO)-2-METHYL-1-PROPANOL;2-methyl-2-(methylamino)-1-Propanol;N-Methyl-2-amino-2-methyl-1-propanol;1-Propanol, 2-methyl-2-(methylamino)-;2-methyl-2-(methylamino)propan-1-ol HCl;2-Methyl-2-(methylamino)propan-1-ol (~85%)
- CBNumber
- CB61210220
- Molecular Formula
- C5H13NO
- Formula Weight
- 103.16
- MOL File
- 27646-80-6.mol
1-Propanol, 2-methyl-2-(methylamino)- Property
- Boiling point:
- 162℃
- Density
- 0.878
- Flash point:
- 62℃
- storage temp.
- 2-8°C(protect from light)
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Colourless Semi-Solid
- pka
- 15.90±0.10(Predicted)
- Appearance
- White to light brown Solid-liquid mixture
Safety
- RIDADR
- UN2735
- HazardClass
- 8
- HS Code
- 2922190090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M330954
- Product name
- 2-Methyl-2-(methylamino)propan-1-ol(~85%)
- Packaging
- 250mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- M330954
- Product name
- 2-Methyl-2-(methylamino)propan-1-ol(~85%)
- Packaging
- 500mg
- Price
- $215
- Updated
- 2021/12/16
- Product number
- 4156-1-10
- Product name
- 2-Methyl-2-(methylamino)propan-1-ol
- Purity
- 95%
- Packaging
- 1g
- Price
- $560
- Updated
- 2021/12/16
- Product number
- 5580AJ
- Product name
- 2-Methyl-2-(methylamino)propan-1-ol
- Packaging
- 5g
- Price
- $755
- Updated
- 2021/12/16
- Product number
- CHM0108653
- Product name
- 2-METHYL-2-(METHYLAMINO)PROPAN-1-OL
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1070.84
- Updated
- 2021/12/16
1-Propanol, 2-methyl-2-(methylamino)- Chemical Properties,Usage,Production
Uses
2-Methyl-2-(methylamino)propan-1-ol functions as an antimicrobial agent for metal-working lubricant oils.
Synthesis
102520-97-8
27646-80-6
General procedure for the synthesis of 2-methyl-2-methylamino-1-propanol from 2-(Boc-amino)-2-methyl-1-propanol: tert-butyl 1-hydroxy-2-methylpropan-2-ylcarbamate (67 g, 354 mmol) was slowly added dropwise under nitrogen protection and at 0 °C to a tetrahydrofuran (THF) solution (150 mL) of LiAlH4 ( 40.3 g, 1062 mmol) in a tetrahydrofuran (THF) solution (400 mL) under stirring. The reaction mixture was stirred at 90 °C overnight and then cooled, followed by quenching by sequential addition of water (40.5 mL), 15% aqueous NaOH solution (40.5 mL) and water (40.5 mL) at 0 °C. The mixture was continued to be stirred for 1 hour and then filtered through diatomaceous earth. The organic layer was dried with sodium sulfate and concentrated in vacuum to give 2-methyl-2-methylamino-1-propanol (28 g, 77% yield) without further purification.LC-MS (ESI) analysis: m/z 104 [M + H]+; retention time 0.24 min.
Toxics Screening Level
Due to a lack of available information, the ITSL is being set at the default value of 0.1 μg/m3 with annual averaging.
References
[1] Patent: WO2014/114694, 2014, A1. Location in patent: Page/Page column 27-28
[2] Journal of the American Chemical Society, 1991, vol. 113, # 23, p. 8879 - 8886
[3] Patent: WO2010/103312, 2010, A1. Location in patent: Page/Page column 10
[4] Patent: WO2016/12916, 2016, A1. Location in patent: Page/Page column 29; 31
1-Propanol, 2-methyl-2-(methylamino)- Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-Propanol, 2-methyl-2-(methylamino)- manufacturers
- Product
- 2-methyl-2-(methylamino)propan-1-ol 27646-80-6
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.9%
- Supply Ability
- 100 tons
- Release date
- 2022-01-17