4(1H)-Pyrimidinone, 2-amino-6-methyl-5-nitro-
- Product Name
- 4(1H)-Pyrimidinone, 2-amino-6-methyl-5-nitro-
- CAS No.
- 4214-85-1
- Chemical Name
- 4(1H)-Pyrimidinone, 2-amino-6-methyl-5-nitro-
- Synonyms
- 2-amino-6-methyl-5-nitropyrimidin-4(3H)-one;2-aMino-6-Methyl-5-nitropyriMidin-4-ol;2-Amino-6-methyl-5-nitro-4(3H)-pyrimidinone;2-amino-6-methyl-5-nitropyrimidin-4(1H)-one;2-amino-6-methyl-5-nitro-1H-pyrimidin-4-one;2-amino-4-hydroxy-6-methyl-5-nitropyrimidine;2-azanyl-6-methyl-5-nitro-1H-pyrimidin-4-one;2-Amino-6-methyl-5-nitro-3H-pyrimidine-4-one;2-AMINO-4-HYDROXY-5-NITRO-6-METHYL-PYRIMIDINE;4(1H)-Pyrimidinone, 2-amino-6-methyl-5-nitro-
- CBNumber
- CB61211393
- Molecular Formula
- C5H6N4O3
- Formula Weight
- 170.13
- MOL File
- 4214-85-1.mol
4(1H)-Pyrimidinone, 2-amino-6-methyl-5-nitro- Property
- Melting point:
- >300 °C
- Boiling point:
- 305.9±45.0 °C(Predicted)
- Density
- 1.83±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C, protect from light
- pka
- 7.18±0.50(Predicted)
- Appearance
- Light yellow to yellow Powder
Safety
- HazardClass
- IRRITANT
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 50736
- Product name
- 2-AMINO-6-METHYL-5-NITROPYRIMIDIN-4(3H)-ONE
- Purity
- 97%
- Packaging
- 1G
- Price
- $37
- Updated
- 2026/04/30
- Product number
- 50736
- Product name
- 2-AMINO-6-METHYL-5-NITROPYRIMIDIN-4(3H)-ONE
- Purity
- 97%
- Packaging
- 5G
- Price
- $159
- Updated
- 2026/04/30
- Product number
- 50736
- Product name
- 2-AMINO-6-METHYL-5-NITROPYRIMIDIN-4(3H)-ONE
- Purity
- 97%
- Packaging
- 25G
- Price
- $617
- Updated
- 2026/04/30
- Product number
- A898778
- Product name
- 2-Amino-6-methyl-5-nitro-3H-pyrimidin-4-one
- Packaging
- 1g
- Price
- $200
- Updated
- 2021/12/16
- Product number
- FA139523
- Product name
- 2-Amino-6-methyl-5-nitropyrimidin-4(3H)-one
- Packaging
- 500mg
- Price
- $85
- Updated
- 2021/12/16
4(1H)-Pyrimidinone, 2-amino-6-methyl-5-nitro- Chemical Properties,Usage,Production
Synthesis
3977-29-5
4214-85-1
The general procedure for the synthesis of 2-amino-6-methyl-5-nitro-3H-pyrimidin-4-one from 2-amino-4-hydroxy-6-methylpyrimidine was as follows: 2-amino-6-methylpyrimidin-4(3H)-one (50 g, 0.4 mol) was dissolved in 250 mL of concentrated sulfuric acid at 0°C, and 40 mL of concentrated nitric acid was slowly added through a dropping funnel. The reaction mixture was stirred at room temperature for 3 hours and then slowly poured into 3.6 L of diethyl ether and continued stirring for 15 minutes. The ether layer was decanted off and 1.0 L of ethyl acetate was added to the remaining solid and stirred for 10 hours. The solid product (54.8 g, 81% yield) was collected by filtration, which could be used in subsequent reactions without further purification.
References
[1] Synthetic Communications, 2009, vol. 39, # 12, p. 2244 - 2249
[2] Journal of Heterocyclic Chemistry, 2009, vol. 46, # 6, p. 1151 - 1153
[3] Journal of Organic Chemistry, 1995, vol. 60, # 24, p. 7947 - 7952
[4] Patent: WO2006/122003, 2006, A2. Location in patent: Page/Page column 32; 34
[5] Nucleosides and Nucleotides, 1999, vol. 18, # 3, p. 363 - 376
4(1H)-Pyrimidinone, 2-amino-6-methyl-5-nitro- Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4(1H)-Pyrimidinone, 2-amino-6-methyl-5-nitro- manufacturers
- Product
- 2-Amino-6-methyl-5-nitropyrimidin-4(3H)-one 4214-85-1
- Price
- US $20.00-100.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200000KG
- Release date
- 2024-08-09
- Product
- 4(1H)-Pyrimidinone, 2-amino-6-methyl-5-nitro- 4214-85-1
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 98%MIN
- Supply Ability
- ASK
- Release date
- 2019-12-25