waltonitone
- Product Name
- waltonitone
- CAS No.
- 1252676-55-3
- Chemical Name
- waltonitone
- Synonyms
- waltonitone;product/153019;waltonitone USP/EP/BP;Urs-12-en-3-one, 28-hydroxy-
- CBNumber
- CB61229266
- Molecular Formula
- C30H48O2
- Formula Weight
- 440.7
- MOL File
- 1252676-55-3.mol
waltonitone Property
- Boiling point:
- 521.6±50.0 °C(Predicted)
- Density
- 1.05±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 15 mg/mL (34.04 mM);;
- pka
- 15.09±0.10(Predicted)
N-Bromosuccinimide Price
- Product number
- orb104702
- Product name
- Waltonitone
- Purity
- >98%,Standard References Grade
- Packaging
- 20mg
- Price
- $569.5
- Updated
- 2021/12/16
- Product number
- DCC-080
- Product name
- Waltonitone
- Purity
- >98%,StandardReferencesGrade
- Packaging
- 20mg
- Price
- $280
- Updated
- 2021/12/16
waltonitone Chemical Properties,Usage,Production
Uses
Waltonitone is a pentacyclic triterpenoid compound isolated from waltonione. Some studies shown that Waltonitone is a potential anti-tumor drug which can inhibit the proliferation of lung cancer A549 cells and promote their apoptosis.
Biological Activity
Waltonitone is a kind of ursane-type pentacyclic triterpenes that can be extracted from the long-stemmed chinensis, which has antitumor activity.
in vitro
waltonitone (10 μM, 25 μM; for 48 hours) results in an increment of sub-G1 population in BEL-7402 cells.
Waltonitone (25 μM; for 48 hours) induces BEL-7402 apoptosis cells.
Waltonitone (25 μM; for 48 hours) can effectively activate caspase-3 in BEL-7402 cells.
in vivo
Waltonitone (iv; 20 mg/kg or 50 mg/kg; once every two days for 16 days) inhibits BEL-7402 tumor growth in male athymic mice (BALB/c nu/nu) in vivo. < br/>
waltonitone Preparation Products And Raw materials
Raw materials
Preparation Products
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