ChemicalBook > CAS DataBase List > 1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl-

1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl-

Product Name
1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl-
CAS No.
129075-56-5
Chemical Name
1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl-
Synonyms
Pd 128763;3,4-Dihydro-5-methoxyisoquinolin-1(2H)one;3,4-dihydro-5-methyl-1(2H)-isoquinolinone;1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl-;5-Methyl-1,2,3,4-tetrahydroisoquinolin-1-one
CBNumber
CB61237386
Molecular Formula
C10H11NO
Formula Weight
161.2
MOL File
129075-56-5.mol
More
Less

1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl- Property

Boiling point:
413.8±45.0 °C(Predicted)
Density 
1.111
storage temp. 
Sealed in dry,Room Temperature
pka
15.12±0.20(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Ark Pharm
Product number
P000309591
Product name
5-Methyl-3,4-dihydroisoquinolin-1(2H)-one
Purity
90%
Packaging
100mg
Price
$92
Updated
2021/12/16
Ark Pharm
Product number
P000309591
Product name
5-Methyl-3,4-dihydroisoquinolin-1(2H)-one
Purity
90%
Packaging
250mg
Price
$153
Updated
2021/12/16
Ark Pharm
Product number
P000309591
Product name
5-Methyl-3,4-dihydroisoquinolin-1(2H)-one
Purity
90%
Packaging
1g
Price
$384
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM1027011
Product name
1(2H)-ISOQUINOLINONE, 3,4-DIHYDRO-5-METHYL-
Purity
95.00%
Packaging
5MG
Price
$498.43
Updated
2021/12/16
Ark Pharm
Product number
P000309591
Product name
5-Methyl-3,4-dihydroisoquinolin-1(2H)-one
Purity
90%
Packaging
5g
Price
$1161
Updated
2021/12/16
More
Less

1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl- Chemical Properties,Usage,Production

Definition

ChEBI: 3,4-dihydro-5-methylisoquinolinone is a member of isoquinolines.

Synthesis

24644-78-8

129075-56-5

General procedure for the synthesis of 5-methyl-3,4-dihydroisoquinolin-1-one from 4-methyl-2,3-dihydro-1H-inden-1-one: 4.7 g (32.2 mmol) of 2,3-dihydro-4-methyl-1H-inden-1-one was mixed with 53 g of trichloroacetic acid and heated to 65°C. To the reaction mixture was added 4.2 g (64.4 mmol) of azide Sodium azide was added to the reaction mixture and the reaction was kept at 65°C for 18 hours. Subsequently, 1.0 g of sodium azide was added and heating was continued for 4 hours. After completion of the reaction, the mixture was diluted with 200 ml of ice water and extracted with ether. The ether extract was washed sequentially with water and saturated sodium bicarbonate solution, dried over anhydrous magnesium sulfate and concentrated. The residue was purified by silica gel column chromatography (eluent: ether to ether/methanol 95/5). The resulting product was recrystallized from toluene to give 2.45 g (47% yield) of the target compound with a melting point of 141°C-143°C.

References

[1] Patent: US5177075, 1993, A

1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl- Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl- Suppliers

China 36 India 2 Switzerland 1 United States 5 Global 44
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4267
Advantage
65
shanghai Rainbow MediTech.Co.Ltd.
Tel
021-64968085,64968086-5815,5812; 13472757003
Fax
+86 21 64968087
Email
xiaoxia.zeng@rainbowpharma.cn
Country
China
ProdList
961
Advantage
65
ShangHai AmK Pharmaceutical Technology Co., Ltd.
Tel
微信 17321281695 18019252918
Fax
17321281695
Email
sale@amkchem.com
Country
China
ProdList
15136
Advantage
55
AN PharmaTech Co Ltd
Tel
86(21)68097365
Fax
86(21)33321566
Email
sales@anpharma.net
Country
China
ProdList
4891
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Taian Jiaye Biotechnology Co.Ltd
Tel
13127280945
Email
285424065@qq.com
Country
China
ProdList
9976
Advantage
55
Sichuan BaiPeng Biotechnology Co., Ltd.
Tel
028-65791793 18140026355
Fax
QQ568470422
Email
568470422@qq.com
Country
China
ProdList
9997
Advantage
58
Aikon International Limited
Tel
025-66061636 18013972705
Fax
(3)02557626880
Email
qqyang@aikonchem.com
Country
China
ProdList
15814
Advantage
58
Jinan chemkey pharmaceutical Co., Ltd.
Tel
15610156652
Email
baimingshi@163.com
Country
China
ProdList
981
Advantage
58
More
Less

View Lastest Price from 1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl- manufacturers

Career Henan Chemical Co
Product
1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl- 129075-56-5
Price
US $5.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2020-01-12

129075-56-5, 1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl-Related Search:

3,4-Dihydro-2H-benzo[1,4]oxazine-7-carbonitrile tert-Butyl 1,3,4,5-tetrahydro-2H-pyrido-[4,3-b]indole-2-carboxylate 3,4-Dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid 3,4-DIHYDRO-2H-1,4-BENZOXAZIN-7-OL 9-methyl-2,8,10-triazabicyclo[4.4.0]deca-2,4,8,11-tetraen-7-one 3,4-dihydro-2H-1,4-benzoxazin-6-ol 7-HYDROXY-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE 2H-1,4-Benzoxazin-8-amine,3,4-dihydro-(9CI) Pyrido[3,4-d]pyrimidin-4(3H)-one (8CI,9CI) 3,4-Dihydro-1,8-naphthyridin-2(1H)-one 3,4-DIHYDRO-2H-PYRROLO[1,2-A]PYRAZIN-1-ONE 3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-AMINE 2H-1,4-Benzoxazin-8-ol, 3,4-dihydro- (9CI) Pyrimido[4,5-d]pyrimidin-4-ol, 3,4-dihydro- (9CI) 3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE-8-CARBONITRILE HYDROCHLORIDE

  • 1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl-
  • 3,4-dihydro-5-methyl-1(2H)-isoquinolinone
  • 3,4-Dihydro-5-methoxyisoquinolin-1(2H)one
  • Pd 128763
  • 5-Methyl-1,2,3,4-tetrahydroisoquinolin-1-one
  • 129075-56-5